DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10486 and LOC566640

DIOPT Version :9

Sequence 1:	NP_647998.2	Gene:	CG10486 / 38664	FlyBaseID:	FBgn0035647	Length:	706	Species:	Drosophila melanogaster
Sequence 2:	XP_009291426.1	Gene:	LOC566640 / 566640	-ID:	-	Length:	511	Species:	Danio rerio

Alignment Length:	592	Identity:	141/592 - (23%)
Similarity:	224/592 - (37%)	Gaps:	130/592 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    77 KKSETSLPRRSWETDDYIDFDDLLPMIGQFGRFQIRLFLFMIPFCFITAFVYLGQIF-MCLTPPK 140
            ||...:.||.:                   |..||.:|..:....|.|||.:...:| :.:||
Zfish     2 KKDAAAFPRLA-------------------GTLQIHVFAILTLPIFFTAFTFFVDVFTLHITP-- 45

  Fly   141 YYCYVPELLHTPVELRKELSIPKEKDGSYSRCRMYNTNYTKIHFAENPSAYINTSLPTIPCKKGY 205
              |.|.....|         :.:..|.:.|....:..|::      :|     ||..|  |.|..
Zfish    46 --CSVDIATKT---------LNRSVDSNVSIFASWTDNHS------DP-----TSSQT--CLKAN 86

  Fly   206 VFEQEGRAFESATMEFGWLCDDDKYATYAQIIFFLGSILGGLAYGHFADHCGRVAALVSSCFLAL 270
            .|                        .:.|..:..|.::|.|..|..:|..|:...|:....:..
Zfish    87 HF------------------------AHGQATYMTGLLIGSLIGGALSDKYGKKILLICCTAIHA 127

  Fly   271 VGSLATSMSTDFFTFAISRFLVGASYDTCFTMVYILVLEYVGPKYRTLVANLSLALFYSPFTMVM 335
            |.::..:.......:..:|.:.|.|........|.|.:|:..||||.....| .:..:|...|.:
Zfish   128 VATVIVAFLPYVPVYLTARAISGVSCCAIHICTYSLGVEWSLPKYRIWPPTL-FSFIFSLGMMGL 191

  Fly   336 PWIALSAGNWRRFSSFTSLPIVLAMFSFCLLPESARWLVSVGEIDKALEILKNVIEVNKKQVSKE 400
            ..:|..:..|.:|.....:|.:|.:..:..||||.|||:    ::|.::.|::.  .|:....|.
Zfish   192 AAVAFLSSTWIQFHLALGIPQILFLPLYFFLPESPRWLL----LNKRMKTLESY--QNRSSKDKR 250

  Fly   401 ILDLF------EASCTQFYKEELDGR----DFTVLSIFKRKRMARYMILMILIWMSISLVYDG-- 453
            .|||.      ||..:...|...:.|    :||...|..|      :.:|..|..:.:|.|.|
Zfish   251 YLDLLLHSVDNEAQKSLSEKSSTETRSNFTNFTSPIILLR------LFIMSYIGFASALTYYGIC 309

  Fly   454 -HVRAASVLDSENIFLFFTIACATELPGNILVILTLDRAGRR---WCSFFYTSLSGVFSLLGASF 514
             .:.:..|    ||:|....:..:|.|..:|..| |.|.|||   ..|.|.:.:|.:.|||.:.|
Zfish   310 FSIGSFGV----NIYLAQFFSGLSEAPSLLLPFL-LKRWGRRPFTMGSLFLSGISCMLSLLVSKF 369

  Fly   515 QNRANMRMS-ALAGRFFSNICYNIGLQWAAEILPTVVRAQGVAFIHTMGFVAML----MSP---- 570
            .|...:.|: ||.|:......|.:...:..|:.|||:|.:.|..:.....||.:    |||
Zfish   370 CNMPALVMTLALMGKLCMQSTYCVSTLYGIELFPTVIRQKCVGVVSLCYRVACIINAVMSPEGGI 434

  Fly   571 PVVYLSKKSLSSTLIVLGALGIFGGLLALFLPETLNHELPETLSDGAQFGKNQRIWHMPCCGPGS 635
            |:         ..:|......|.|..|.|.||||....||:|:.   :..|..|: .:.||..||
Zfish   435 PL---------PAMISYSGGPIIGAALCLLLPETSGIPLPDTVH---ECEKQPRL-KLSCCACGS 486

  Fly   636 ----RKS 638
                |||
Zfish   487 IKPTRKS 493

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10486	NP_647998.2	2A0119	104..612	CDD:273328	127/533 (24%)
CG10486	NP_647998.2	MFS	231..602	CDD:119392	97/395 (25%)
LOC566640	XP_009291426.1	MFS	93..455	CDD:119392	95/388 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170588874
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	3.030