Protein Alignment CG10486 and Slc22a21

DIOPT Version :9

• Sequence 1: NP_647998.2
• Gene: CG10486 / 38664
• FlyBaseID: FBgn0035647
• Length: 706
• Species: Drosophila melanogaster
• Sequence 2: NP_062697.1
• Gene: Slc22a21 / 56517
• MGIID: 1929481
• Length: 564
• Species: Mus musculus
• Alignment Length: 586
• Identity: 153/586 - (26%)
• Similarity: 261/586 - (44%)
• Gaps: 49/586 - (8%)

  Fly    94 IDFDDLLPMIGQFGRFQIRLFLFMIPFCFI-TAFVYLGQIFMCLTPPKYYCYVPELLHTPVELRK 157
            :|:|::...:|::|.|| ||..|::....| ..|..|..:|:... |::.|.:|:.::.....|.
Mouse     2 LDYDEVTAFLGEWGTFQ-RLIFFLLSASIIPNGFTGLSAVFLTAI-PEHRCRIPDTVNLSSAWRN 64

  Fly   158 ELSIPKE-KDGSY--SRCRMYNTNYTKIHFAE---NPSAYIN-TSLPTIPCKKGYVFEQEGRAFE 215
            . |||.| |||..  .:||.|.. .|..:|:|   .|...:: ..|....|..|:.::::  .|.
Mouse    65 H-SIPMETKDGPEVPQKCRRYRL-ATIANFSELGLEPGRDVDLEQLEQENCLDGWEYDKD--IFL 125

  Fly   216 SATM-EFGWLCDDDKYATYAQIIFFLGSILGGLAYGHFADHCGRVAALVSSCFLALVGSLATSMS 279
            |..: |:..:|.||..|......|::|.:||....|..:|..||...|..:..:....|.....|
Mouse   126 STIVTEWDLVCKDDWKAPLTTSFFYVGVLLGSFISGQLSDRFGRKNILFLTMAMHTGFSFIQVFS 190

  Fly   280 TDFFTFAISRFLVGASYDTCFTMVYILVLEYVGPKYRTLVANLSLALFYSPFTMVMPWIALSAGN 344
            .:|..|.:...|||..:.:.:...::|..|.:....|.:.|.|.:.:|::...||:|..|.....
Mouse   191 VNFEMFTLLYTLVGMGHISNYVAAFVLGTEMLSKSVRIIFATLGVCIFFAFGFMVLPLFAYFIRE 255

  Fly   345 WRRFSSFTSLPIVLAMFSFCLLPESARWLVSVGEIDKALEILKNVIEVNKKQVSKEILDLFEASC 409
            |||.....:||.||....:..:|||.|||:|.|.|.:|..|::...::|.......|.|..|.:.
Mouse   256 WRRLLLAITLPGVLCGALWWFIPESPRWLISQGRIKEAEVIIRKAAKINGIVAPSTIFDPSETNK 320

  Fly   410 TQFYKEELDGRDFTVLSIFKRKRMARYMILMILIWMSISLVYDGHVRAASVLDSE----NIFLFF 470
            .|....: ..:...:..:.:...:....|:.|::|::||:.|.|     ..||:.    ||::..
Mouse   321 LQDDSSK-KPQSHHIYDLVRTPNIRILTIMSIILWLTISVGYFG-----LSLDTPNLNGNIYVNC 379

  Fly   471 TIACATELPGNILVILTLDRAGRRWCSFFYTSLSGVFSLLGASFQNRANMRMS---------ALA 526
            .:..|.|:|..:|..|.|....||:      |::|.. .||.|......:..|         .:.
Mouse   380 FLLAAVEVPAYVLAWLLLQHVSRRY------SMAGSL-FLGGSVLLLVQLVPSDLHYLSTTLVMV 437

  Fly   527 GRFFSNICYNIGLQWAAEILPTVVRAQGVAFIHTMGFVAMLMSPPVVYLSKKSLSSTLIVLGALG 591
            |:|.....|::...:.||:.|||||..||....|...:..::||..|||.........|::|:|.
Mouse   438 GKFGITSAYSMVYVYTAELYPTVVRNMGVGVSSTASRLGSILSPYFVYLGAYDRRLPYILMGSLT 502

  Fly   592 IFGGLLALFLPETLNHELPETLSDGAQFGKNQRIWHMPCCGPGSRKSHPRHNWHQGSSLRTLSKD 656
            |...::.||.||:....||||:.:..:..|.::...:      |:|..|:.:  :|:..||....
Mouse   503 ILTAIITLFFPESSGVSLPETIDEMQKVKKLKQRQSL------SKKGSPKES--KGNVSRTSRTS 559

  Fly   657 E 657
            |
Mouse   560 E 560

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10486	NP_647998.2	2A0119	104..612	CDD:273328	141/529 (27%)
		MFS	231..602	CDD:119392	99/383 (26%)
Slc22a21	NP_062697.1	2A0119	12..523	CDD:273328	141/529 (27%)
		MFS	123..513	CDD:119392	105/402 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	532..564		8/37 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167843888
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9N9
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.850