Protein Alignment CG10486 and SVOP

DIOPT Version :9

• Sequence 1: NP_647998.2
• Gene: CG10486 / 38664
• FlyBaseID: FBgn0035647
• Length: 706
• Species: Drosophila melanogaster
• Sequence 2: NP_061181.1
• Gene: SVOP / 55530
• HGNCID: 25417
• Length: 548
• Species: Homo sapiens
• Alignment Length: 681
• Identity: 131/681 - (19%)
• Similarity: 229/681 - (33%)
• Gaps: 223/681 - (32%)

  Fly     8 NASTEDDDKPKKREHRDQGQQSKLKKIKYYIEPDKVDIGIQAGDSLEKVKVTYVEPDDEESSHGF 72
            :|.:|||....:.|.:.:|                |.:|::|           ||.||
Human    22 SARSEDDTASGEHEVQIEG----------------VHVGLEA-----------VELDD------- 52

  Fly    73 FWGKKKSETSLPRR-SWETDDYIDFDDLLPMIGQFGRFQIRLFLFMIPFCFITAFVYLG----QI 132
                   ..::|:. :..|||....:|.:..|| ||:||.:|.:       :|...::.    .:
Human    53 -------GAAVPKEFANPTDDTFMVEDAVEAIG-FGKFQWKLSV-------LTGLAWMADAMEMM 102

  Fly   133 FMCLTPPKYYCYVPELLHTPVELRKELSIPKEKDGSYSRCRMYNTNYTKIHFAENPSAYINTSLP 197
            .:.:..|:.:|              |..:|
Human   103 ILSILAPQLHC--------------EWRLP----------------------------------- 118

  Fly   198 TIPCKKGYVFEQEGRAFESATMEFGWLCDDDKYATYAQIIFFLGSILGGLAYGHFADHCGRVAAL 262
                                    .|     :.|....:: |:|.:.....:|:.:|..||...|
Human   119 ------------------------SW-----QVALLTSVV-FVGMMSSSTLWGNISDQYGRKTGL 153

  Fly   263 VSSCFLALVGSLATSMSTDFFTFAISRFLVGASYDTCFTMVYILVLEYVGPKYRTLVANLSLALF 327
            ..|....|...:.::.:..:....:.|.|||.........| .|..|::..|.|.... |.:.:|
Human   154 KISVLWTLYYGILSAFAPVYSWILVLRGLVGFGIGGVPQSV-TLYAEFLPMKARAKCI-LLIEVF 216

  Fly   328 Y---SPFTMVMPWIALSAGNWRRFSSFTSLPIVLAMFSFCLLPESARWLVSVGEIDKALEILKNV 389
            :   :.|.:|:....:.:..||.....:::|::|.......||||||:.|..|..:||:..||.:
Human   217 WAIGTVFEVVLAVFVMPSLGWRWLLILSAVPLLLFAVLCFWLPESARYDVLSGNQEKAIATLKRI 281

  Fly   390 IEVN-------KKQVSKE-----ILDLFEASCTQFYKEELDGRDFTVLSIFKRKRMARYMILMIL 442
            ...|       |..:|::     :.|||    |..::       :|.|             |:..
Human   282 ATENGAPMPLGKLIISRQEDRGKMRDLF----TPHFR-------WTTL-------------LLWF 322

  Fly   443 IWMSISLVYDGHV-------RAASVLD-------------------SENIFLFFTIACATELPGN 481
            ||.|.:..|.|.|       :|..|..                   ||..::.......:|.||.
Human   323 IWFSNAFSYYGLVLLTTELFQAGDVCGISSRKKAVEAKCSLACEYLSEEDYMDLLWTTLSEFPGV 387

  Fly   482 ILVILTLDRAGRR------WCSFFYTSLSGVFSLLGASFQNRANMRMSALAGRFFSNICYNIGLQ 540
            ::.:..:||.||:      :..|.:.||. :|..:|     |..:.:.....|.|.:..:.....
Human   388 LVTLWIIDRLGRKKTMALCFVIFSFCSLL-LFICVG-----RNVLTLLLFIARAFISGGFQAAYV 446

  Fly   541 WAAEILPTVVRAQGVAFIHTMGFVAMLMSPPVV-YLSKKSLSSTLIVLGALGIFGGLLALFLP-E 603
            :..|:.||..||.|:.....|..|..|::|.:. .:.:.|:..||.|.....:...|.:.||| |
Human   447 YTPEVYPTATRALGLGTCSGMARVGALITPFIAQVMLESSVYLTLAVYSGCCLLAALASCFLPIE 511

  Fly   604 TLNHELPETLSDGAQFGKNQRIWHMPCCGPG 634
            |....|.|:         :.|.|.....|.|
Human   512 TKGRGLQES---------SHREWGQEMVGRG 533

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10486	NP_647998.2	2A0119	104..612	CDD:273328	107/560 (19%)
		MFS	231..602	CDD:119392	90/418 (22%)
SVOP	NP_061181.1	MFS_SVOP	87..509	CDD:340999	96/539 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910