Protein Alignment CG10486 and CG7458

DIOPT Version :9

• Sequence 1: NP_647998.2
• Gene: CG10486 / 38664
• FlyBaseID: FBgn0035647
• Length: 706
• Species: Drosophila melanogaster
• Sequence 2: NP_649374.1
• Gene: CG7458 / 40441
• FlyBaseID: FBgn0037144
• Length: 572
• Species: Drosophila melanogaster
• Alignment Length: 595
• Identity: 154/595 - (25%)
• Similarity: 260/595 - (43%)
• Gaps: 68/595 - (11%)

  Fly    60 YVEPDDEESSHGFFWGKKKSETSLPRRSWETDDYIDFDDLLPMIGQFGRFQ-IRLFLFMIPFCFI 123
            |...|.:.:.|.      .:|.:......:.|:  ..|.:|..||||||:| |...|..:|..|
  Fly    10 YRRSDSKTTGHA------DAEAATQTAGGDEDN--SLDAILVRIGQFGRYQIINYVLLCVPMLF- 65

  Fly   124 TAFVYLGQIFMCLTPPKYYCYVPELLHTPVELRKE----LSIPKEKDGSYSRCRMYNTN------ 178
            .||..:..:|...| ..:.|.||: ..:|..:.:|    .:||| |:.::..|..|..|
  Fly    66 NAFFSISYVFTAST-VVHRCTVPQ-CDSPSSVYEEDWLGFTIPK-KNSAWDDCHRYAANISDAIS 127

  Fly   179 -YTKIHFAENPSA------YINTSLPTIPCKKGYVFEQEGRAFESATMEFGWLCDDDKYATYAQI 236
             ||      :||.      |...:..|  |.:.:.|..|.:...:   |||..|:|:...:....
  Fly   128 GYT------DPSGQYCLKEYFTITSET--CGRDFKFRDEEKTIST---EFGIYCEDEWKLSMVGT 181

  Fly   237 IFFLGSILGGLAYGHFADHCGRVAAL-VSSCFLALVGSLATSMSTDFFTFAISRFLVGASYDTCF 300
            |..:|..:|....|:|||..||...| |:....||:| :..|:|:::..|.:..||..|...|.|
  Fly   182 INNVGQFVGIPLGGYFADRYGRRTMLAVAGSVSALMG-VIRSLSSNYSMFLVFEFLDMAVGSTLF 245

  Fly   301 TMVYILVLEYVGPKYRTLVANLSLALFYSPFTMVMPWIALSAGNWRRFSSFTSLPIVLAMFSFCL 365
            ...::|.:|.||||.|...|.: :.:||:.....:.::|....:||........|.||.:....:
  Fly   246 PTAFLLAIELVGPKRRVAAATI-ITIFYALGEAFLGFLASQVQHWRWLLRVLYAPAVLQILFLWI 309

  Fly   366 LPESARWLVSVGEIDKALEILKNVIEVNKKQVSKEIL-DLFEASCTQFYKEELDGRDFTVLS--I 427
            ||||.|||:|.|..:||..:|:....:|::.:.:|.| ||..::..:.  .:.:...:.::.  :
  Fly   310 LPESVRWLLSQGAEEKASNVLRRAARINQRPLPEEQLNDLLTSNRQKL--SQANESQYPIMRAVV 372

  Fly   428 FKRKRMARYMILMILIWMSISLVYDGHVRAASVLDSENIFLFFTIACATELPGNILVILTLDRAG 492
            |...|:|.    ..|.|.:.:|:..| :...||....|.:..|.:....::||.:|.::.:||.|
  Fly   373 FFSLRIAN----CCLCWFTHTLIALG-LSLNSVNLGGNKYTNFMLNGFIQIPGLLLPLVIMDRVG 432

  Fly   493 RRWCSFFYTSLSGVFSL----LGAS----FQNRANMRMSALAGRFFSNICYNIGLQWAAEILPTV 549
            ||      .||.....|    :|||    ..|.|......|.|:......:.|...:.:||.||.
  Fly   433 RR------HSLCASMLLCAICMGASAAVPADNYAGSLALFLIGKLAITCSFQILYFFTSEIFPTN 491

  Fly   550 VRAQGVAFIHTMGFVAMLMSPPVVYLSKKSLSSTLIVLGALGIFGGLLALFLPETLNHELPETLS 614
            ||...::....:|.:..:::|....|:|..:.:..|:.....:..|.|.|..|||.:..||.|:.
  Fly   492 VRNTLLSLCSMVGRIGSMLAPQTPLLAKYYIYAPQILFATFALISGFLTLAFPETADKVLPTTIE 556

  Fly   615 DGAQFGKNQR 624
            :.....:.:|
  Fly   557 EARDLNQAKR 566

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10486	NP_647998.2	2A0119	104..612	CDD:273328	144/537 (27%)
		MFS	231..602	CDD:119392	99/382 (26%)
CG7458	NP_649374.1	2A0119	46..554	CDD:273328	144/537 (27%)
		MFS	161..544	CDD:119392	104/400 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45458497
Domainoid	1	1.000	100	1.000	Domainoid score	I351
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	97	1.000	Inparanoid score	I321
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.990