Protein Alignment CG10486 and slc22a7b.1

DIOPT Version :10

• Sequence 1: NP_647998.2
• Gene: CG10486 / 38664
• FlyBaseID: FBgn0035647
• Length: 706
• Species: Drosophila melanogaster
• Sequence 2: NP_956643.1
• Gene: slc22a7b.1 / 393320
• ZFINID: ZDB-GENE-040426-1311
• Length: 546
• Species: Danio rerio
• Alignment Length: 538
• Identity: 139/538 - (25%)
• Similarity: 252/538 - (46%)
• Gaps: 38/538 - (7%)

  Fly    96 FDDLLPMIGQFGRFQIRLF-LFMIPFCFITAFVYLGQIFMCLTPPKYYCYVPELLHTPV------ 153
            |::||..:|.||::|..|. |.:||...:.....|......:  |.::|.:..|....:
Zfish     3 FENLLAEVGGFGKYQFCLMALLVIPRVTLPCHFLLNNFIAAI--PSHHCDISSLSADGIFGNLTQ 65

  Fly   154 ELRKELSIPKEKDGSYSRCRMYNTNYTKIHFAENPSAYINTSLPTIPCKKGYVFEQEGRAFESA- 217
            |.|..:.:|.::||:...|.|:  ::.:.....|.|:  ::.||.:.|:.|:.|:..  .|:|.
Zfish    66 EERLTVGVPAQEDGTPVSCHMF--SHPQFQLLINSSS--SSDLPVVECQNGWRFDNS--TFKSTL 124

  Fly   218 TMEFGWLCDDDKYATYAQIIFFLGSILGGLAYGHFADHCGRVAALVSSCFLALVGSLATSMSTDF 282
            ..||..:||..........|||.|.::|...:|...|..||...|:.:..:::...:|::.:..|
Zfish   125 ATEFDLVCDRRGLNKATATIFFAGVMIGAAIFGWLTDRFGRKRMLMLAYLISITFGVASAFAQSF 189

  Fly   283 FTFAISRFLVGASYDTCFTMVYILVLEYVGPKYRTLVANLSLALFYSPFTMVMPWIALSAGNWRR 347
            ..|||.||..|........:..:|.:|:....:|| :|.:.::|.:|...|::..:|....:||.
Zfish   190 IVFAIMRFFTGMGLTGISIISIVLCIEWADIAHRT-IAGVMISLDWSLSCMILSGVAYLVNDWRA 253

  Fly   348 FSSFTSLPIVLAMFSFCLLPESARWLVSVGEIDKALEILKNVIEVNKKQVSKEILDLFEASCTQF 412
            .....:.||.|||.::..||||||||::.|::::|...|.....||.:|  ..:.|:...:....
Zfish   254 LILTVTAPIALAMITWRWLPESARWLIANGKLEEAHFYLSKCASVNNRQ--HNLRDIKPETLANV 316

  Fly   413 YKEELDGRDFTVLSIFKRKRMARYMILMILIWMSISLVYDG---HVRAASVLDSENIFLFFTIAC 474
            ...:...|.::.|.:.:..:|.:..:|..:.|..::..|.|   ::....:    |::|...|..
Zfish   317 IIADRGDRTYSYLDLVRSSKMRKLAMLTGITWFGVAFTYYGISFNISGFGL----NLYLTQFIYG 377

  Fly   475 ATELPGNILVILTLDRAGRRWCSFFYTSLSGVFSLLGAS-------FQNRANMRMSALAGRFFSN 532
            |.|||..::..:.||:.|||:........:||  .:|.:       :..|.   :.|:.|:.||.
Zfish   378 AIELPSKLVAYVCLDKLGRRYSQVGTMITTGV--CIGITVLIPRVLWVPRT---VIAVLGKGFSE 437

  Fly   533 ICYNIGLQWAAEILPTVVRAQGVAFIHTMGFVAMLMSPPVVYLSKKSLSSTLIVLGALGIFGGLL 597
            ..:.....:..|:.|||:|..|:.:...:|.|.:.::|.|..|.:..|....::..::.|..|||
Zfish   438 ASFTCVFLYTTELYPTVLRQNGLGYSSFIGRVGVSLAPLVSLLDEVWLPLPQVLFCSVAIVAGLL 502

  Fly   598 ALFLPETLNHELPETLSD 615
            ||.||||.|..||||:.|
Zfish   503 ALLLPETHNVRLPETIED 520

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10486	NP_647998.2	2A0119	104..612	CDD:273328	133/525 (25%)
slc22a7b.1	NP_956643.1	MFS_SLC22A7_OAT2	102..507	CDD:341005	105/418 (25%)