Protein Alignment CG10486 and Slc22a14

DIOPT Version :9

• Sequence 1: NP_647998.2
• Gene: CG10486 / 38664
• FlyBaseID: FBgn0035647
• Length: 706
• Species: Drosophila melanogaster
• Sequence 2: NP_001032838.1
• Gene: Slc22a14 / 382113
• MGIID: 2685974
• Length: 629
• Species: Mus musculus
• Alignment Length: 604
• Identity: 133/604 - (22%)
• Similarity: 253/604 - (41%)
• Gaps: 99/604 - (16%)

  Fly    66 EESSHGFFWGKKKS------ETSLPRRSW--------------ETDDYIDFDDLLPMIGQFGRFQ 110
            |:.::...:|.:.|      |.|.|.::|              ..||  .|..::..||:||.||
Mouse     3 EDQNYKTAFGSQNSRDTHRHEISFPSQNWSLEMLLRRLKAIDARRDD--KFASVMDAIGEFGTFQ 65

  Fly   111 IRL-FLFMIPFCFITAFVYLGQIFMCLTPPKYYCYVPELLHTPVELRKE----LSIPKEKDGSYS 170
            .|| .|..||....|.|::.....  ||..:.||....:|.....|.::    |::|:..:||:.
Mouse    66 WRLVVLTFIPSILSTFFIFSHHFL--LTAQRPYCNTSWILEVGPNLTEDEQLNLTLPRAPNGSFL 128

  Fly   171 RCRMY-----NTNYTKIHFAENPSAYINTSLPTIPCKKGYVFEQEGRAF---ESATMEFGWLCDD 227
            .|.||     :.: :.|||..|   |..|      ||.|:::     .|   .|...||..:|.:
Mouse   129 TCLMYIPVPWDLD-SIIHFGLN---YTET------CKFGWIY-----PFAHTRSLINEFDLVCGN 178

  Fly   228 DKYATYAQIIFFLGSILGGLAYGHFADHCGRVAALVSSCFLALVGSLATSMSTDFFTFAISRFLV 292
            :........:|..|.:.|.|.:|..:|..||...::.|....|:....|:..:.|:.:...||.|
Mouse   179 EPNKENGLTVFLSGVLTGSLLFGFLSDKLGRYPIILLSLLGFLIFGFGTAFVSSFYQYLFFRFFV 243

  Fly   293 ---GASYDTCFTMVYILVLEYVGPKYRTLVANLSLALFYSPFTMVMPWIALSAGNWRRFSSFTSL 354
               ...|..|...   ||:|::..::|.....|..: |.:...:::..:|....:||.......:
Mouse   244 AQASVGYAICSVS---LVMEWLVGEHRAQAVILQHS-FLTIGVILLTGLAYKVVHWRLLCLLGGM 304

  Fly   355 PIVLAMFSFCLLPESARWLVSVGEIDKALEILKNVIEVNKKQVSKEILDLFEASCTQFYKEELDG 419
            |:...:.:..:|.||.|||:..|::::|.::|....|||||.:...:|:..:.|..:..|.
Mouse   305 PMFPLICNIWVLRESPRWLMVRGKVEEAKKVLCYAAEVNKKTIPLNLLNELQISGKKVAKA---- 365

  Fly   420 RDFTVLSIFKRKRMARYMILMILIWMSISLVYDGHVRAASVLDSE------NIFLFFTIACATEL 478
               ::|.....:.:.:.::.:..:|.::|.:       :..|:.:      :::....:.....:
Mouse   366 ---SILDFCTNQHLFKVVLAIGCVWFTVSYI-------SFTLNLKMNDFGLDVYFVQMVRSIVAV 420

  Fly   479 PGNILVILTLDRAGRRWC----SFFYTSLSGVFSLLGASFQNRANMRMSALAGRFFSNICYNIGL 539
            |..:..|:.|:..||:|.    .|..||:  ...||....:.::.:.::.:...|......:|..
Mouse   421 PARLCCIILLEYFGRKWALNLTLFLVTSM--CLFLLFLPQEPKSTIILTLMLAEFSMAGTLSIFF 483

  Fly   540 QWAAEILPTVVRAQGVAFIHTMGFVAMLMSPPVVYLSKKSLSSTLIVLGALGIFGGLLALFLPET 604
            .:.||:||||:|:.|:..: ::.:||..:|...::...|:         .|.||...|...|...
Mouse   484 IYTAELLPTVLRSTGLGMV-SLAWVAGAISSVAIFKQTKT---------QLPIFFCCLCCVLALC 538

  Fly   605 LNHELPET----LSDGAQF 619
            .:..:|||    |.|..::
Mouse   539 FSSLVPETGSQSLRDSIEY 557

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10486	NP_647998.2	2A0119	104..612	CDD:273328	118/533 (22%)
		MFS	231..602	CDD:119392	77/383 (20%)
Slc22a14	NP_001032838.1	2A0119	59..553	CDD:273328	121/540 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167844091
Domainoid	1	1.000	69	1.000	Domainoid score	I9569
eggNOG	1	0.900	-	-		E33208_3B9N9
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.930