DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10486 and SPAPB1E7.08c

DIOPT Version :9

Sequence 1:	NP_647998.2	Gene:	CG10486 / 38664	FlyBaseID:	FBgn0035647	Length:	706	Species:	Drosophila melanogaster
Sequence 2:	NP_594134.1	Gene:	SPAPB1E7.08c / 2543660	PomBaseID:	SPAPB1E7.08c	Length:	554	Species:	Schizosaccharomyces pombe

Alignment Length:	580	Identity:	127/580 - (21%)
Similarity:	218/580 - (37%)	Gaps:	155/580 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   138 PPKYYCYVP------------ELLHTPVELRKELSIPKEKDGSYSRCRMYNTN-YTKIHFAENPS 189
            ||:.|...|            ||:: ||||......|.:.|..     ::::| ::|.:.|:  |
pombe     6 PPRLYDMSPTESKKQEDVSETELVY-PVELADATIQPSKSDDD-----LFDSNDFSKTYLAK--S 62

  Fly   190 AYINTSLPTIPCKK--GYVFEQEGRAFESATMEFGWLCDD-----------------------DK 229
            ..::.::..|...:  .|:|...|         |||:.|:                       :.
pombe    63 RILSNAMNEIGFGRYQWYLFFVAG---------FGWMSDNIWPVCTSLILMRLDEVDGPHPPAEG 118

  Fly   230 YATYAQIIFFLGSILGGLAYGHFADHCGR-----VAALVSSCFLALVGSLATSMSTDFFTFAISR 289
            .|.|..:...||.::|.:.:...||..||     :..|.:..|..:.|:.....|...|. |:..
pombe   119 RAPYLTLSQNLGLLVGAMVWSLSADTIGRRWAFNLTFLFTGVFAVIAGASPNFASICVFD-ALWS 182

  Fly   290 FLVGAS--YDTCFTMVYILVLEYVGPKYRTLVANLSLALFYSPFTMV----MPWIALS------- 341
            |.||.:  .|:.      :.||.:...::.|:..:|   |:.....|    :.|..:|
pombe   183 FGVGGNLPVDSA------IFLEALPSSHQWLLTVMS---FWWAIGQVIANLVSWGLISNFSCPDD 238

  Fly   342 ------AGN--WRRFSSFTSLPIVLAMFSFCLLPESARWLVSV----------GEIDKALEILKN 388
                  |.|  ||.| .||...:.|.||       :||:||||          |:..||:|.:..
pombe   239 ESVCHRADNKGWRYF-LFTMGGMTLLMF-------AARFLVSVYESPKFYLAKGDDYKAVETIHK 295

  Fly   389 VIEVNKKQVSKEILDLFEASCTQFYKEELDG---------------------RDFT---VLSIFK 429
            :..:|.|..:..:.:|:.....:..:.:||.                     |.:.   :...|.
pombe   296 IARINGKTCTLTVEELYAIDRQEQEESDLDDSKSSDAKSVTQGTTNLIVEKLRKYNFEHIRQCFG 360

  Fly   430 RKRMARYMILMILIWMSISLVY-----------DGHVRAASVLDSENIFLFFTIACATELPGNIL 483
            .:::|...||:||.|..|.|.:           :....|...|.....:....|..|..:||:::
pombe   361 SRKLAISSILVILSWAVIGLAFPLYNAFLPYYLETRGNANEPLSVAKTYRNSLIVSAIGVPGSLI 425

  Fly   484 V-ILTLDRAGRRWCSFFYTSLSGVFSLLGASFQNRANMRMSALAG-----RFFSNICYNIGLQWA 542
            . :|...|.||:........|:||| |..::....:|    |..|     .|||:|.|.:...:.
pombe   426 AGVLVEFRIGRKGTLCLSLILTGVF-LFASTTAKTSN----AYLGWNCTFSFFSDIMYGVLYAYT 485

  Fly   543 AEILPTVVRAQGVAFIHTMGFVAMLMSPPVVYLSKKSLSSTLIVLGALGIFGGLLALFLP 602
            .|:.|:.||...|....:...:..:.||.:...:..:.|:.:.|.|||.||.|:|.:|.|
pombe   486 PEVFPSKVRGTAVGLAASANRILGIFSPVIAMRANLTTSAPIFVSGALFIFAGILVVFFP 545

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10486	NP_647998.2	2A0119	104..612	CDD:273328	127/580 (22%)
CG10486	NP_647998.2	MFS	231..602	CDD:119392	102/447 (23%)
SPAPB1E7.08c	NP_594134.1	2A0109	68..552	CDD:129965	111/510 (22%)
SPAPB1E7.08c	NP_594134.1	MFS	122..545	CDD:119392	101/445 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	79	1.000	Domainoid score	I2349
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	86	1.000	Inparanoid score	I1789
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.050