Protein Alignment CG10486 and Slc22a5

DIOPT Version :9

• Sequence 1: NP_647998.2
• Gene: CG10486 / 38664
• FlyBaseID: FBgn0035647
• Length: 706
• Species: Drosophila melanogaster
• Sequence 2: NP_035526.1
• Gene: Slc22a5 / 20520
• MGIID: 1329012
• Length: 557
• Species: Mus musculus
• Alignment Length: 541
• Identity: 147/541 - (27%)
• Similarity: 242/541 - (44%)
• Gaps: 44/541 - (8%)

  Fly    95 DFDDLLPMIGQFGRFQIRLFLFMIPFCFI-TAFVYLGQIFMCLTPPKYYCYVPELLHTPVELRKE 158
            |:|::...:|::|.|| ||..|::....| ..|..:..:|:..| |::.|.||..::.....|..
Mouse     3 DYDEVTAFLGEWGPFQ-RLIFFLLSASIIPNGFNGMSIVFLAGT-PEHRCLVPHTVNLSSAWRNH 65

  Fly   159 LSIPKE-KDGSY--SRCRMYNTNYTKIHFAE---NPSAYIN-TSLPTIPCKKGYVFEQEGRAFES 216
             |||.| |||..  .:||.|.. .|..:|:|   .|...:: ..|....|..|:.::::  .|.|
Mouse    66 -SIPLETKDGRQVPQKCRRYRL-ATIANFSELGLEPGRDVDLEQLEQESCLDGWEYDKD--VFLS 126

  Fly   217 ATM-EFGWLCDDDKYATYAQIIFFLGSILGGLAYGHFADHCGRVAALVSSCFLALVGSLATSMST 280
            ..: |:..:|.||..|.....:||:|.::|....|..:|..||...|..:..:....|.....|.
Mouse   127 TIVTEWDLVCKDDWKAPLTTSLFFVGVLMGSFISGQLSDRFGRKNVLFLTMGMQTGFSFLQVFSV 191

  Fly   281 DFFTFAISRFLVGASYDTCFTMVYILVLEYVGPKYRTLVANLSLALFYSPFTMVMPWIALSAGNW 345
            :|..|.:...|||....:.:...::|..|.:....|.:.|.|.:.:||:...||:|..|....:|
Mouse   192 NFEMFTVLFVLVGMGQISNYVAAFVLGTEILSKSIRIIFATLGVCIFYAFGFMVLPLFAYFIRDW 256

  Fly   346 RRFSSFTSLPIVLAMFSFCLLPESARWLVSVGEIDKALEILKNVIEVNKKQVSKEILDLFEASCT 410
            |......::|.||....:..:|||.|||:|.|.|.:|..|::...::|.......|.|..|....
Mouse   257 RMLLLALTVPGVLCGALWWFIPESPRWLISQGRIKEAEVIIRKAAKINGIVAPSTIFDPSELQDL 321

  Fly   411 QFYKEELDGRDFTVLSIFKRKRMARYMILMILIWMSISLVYDGHVRAASVLDSEN----IFLFFT 471
            ...|.:|    ..:..:.:.:.:....|:.|::|::||:.|.|     ..||:.|    |::...
Mouse   322 NSTKPQL----HHIYDLIRTRNIRVITIMSIILWLTISVGYFG-----LSLDTPNLHGDIYVNCF 377

  Fly   472 IACATELPGNILVILTLDRAGRRWCSFFYTSLSGVFSLLGAS---FQNRANMRMSALA------G 527
            :..|.|:|..:|..|.|....||:      |:|... .||.|   |.......:..|:      |
Mouse   378 LLAAVEVPAYVLAWLLLQYLPRRY------SISAAL-FLGGSVLLFMQLVPSELFYLSTALVMVG 435

  Fly   528 RFFSNICYNIGLQWAAEILPTVVRAQGVAFIHTMGFVAMLMSPPVVYLSKKSLSSTLIVLGALGI 592
            :|.....|::...:.||:.|||||..||....|...:..::||..|||.........|::|:|.|
Mouse   436 KFGITSAYSMVYVYTAELYPTVVRNMGVGVSSTASRLGSILSPYFVYLGAYDRFLPYILMGSLTI 500

  Fly   593 FGGLLALFLPETLNHELPETL 613
            ...:|.||.||:....||:|:
Mouse   501 LTAILTLFFPESFGVPLPDTI 521

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10486	NP_647998.2	2A0119	104..612	CDD:273328	144/529 (27%)
		MFS	231..602	CDD:119392	101/383 (26%)
Slc22a5	NP_035526.1	2A0119	12..520	CDD:273328	144/529 (27%)
		MFS	123..510	CDD:119392	107/402 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167843876
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9N9
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.850