Protein Alignment CG10486 and Slc22a3

DIOPT Version :9

• Sequence 1: NP_647998.2
• Gene: CG10486 / 38664
• FlyBaseID: FBgn0035647
• Length: 706
• Species: Drosophila melanogaster
• Sequence 2: NP_035525.1
• Gene: Slc22a3 / 20519
• MGIID: 1333817
• Length: 551
• Species: Mus musculus
• Alignment Length: 563
• Identity: 154/563 - (27%)
• Similarity: 264/563 - (46%)
• Gaps: 53/563 - (9%)

  Fly    96 FDDLLPMIGQFGRFQIRLFLFMIPFCFITAFVYLGQIFMCLTPPKYYCYVPEL------------ 148
            ||..|...|:|||||.|:||.:.......||:::|.:|:...|..|:|..|..
Mouse     4 FDQALRKAGEFGRFQRRVFLLLCLTGVTFAFLFVGVVFLGSQPDYYWCRGPRATALAERCAWSPE 68

  Fly   149 ----LHTPVELRKELSIPKEKDGSYSRCRMY---NTNYTKIHFAENPSAYINTSLPTIPCKKGYV 206
                |.||     ||.:|.|:.|. ..|..|   .||.:.....:..:|:.|.|.|.:.|...:.
Mouse    69 EEWNLTTP-----ELHVPAERRGQ-GHCHRYLLEATNTSSELSCDPLTAFPNRSAPLVSCSGDWR 127

  Fly   207 FEQEGRAFESATMEFGWLCDDDKYATYAQIIFFLGSILGGLAYGHFADHCGRVAALVSSCFLALV 271
            :.:   ...:...:|..:|.:.......|.|..||.:.|....|:.||..||:...:.|||...:
Mouse   128 YVE---THSTIVSQFDLVCSNAWMLDLTQAILNLGFLAGAFTLGYAADRYGRLIIYLISCFGVGI 189

  Fly   272 GSLATSMSTDFFTFAISRFLVG----ASYDTCFTMVYILVLEYVGPKYRTLVANLSLALFYSPFT 332
            ..:..:.:.:|..|.|.|||.|    .::.|||    ::|.|.||.|.|.:| .:.:.:|::...
Mouse   190 TGVVVAFAPNFSVFVIFRFLQGVFGKGAWMTCF----VIVTEIVGSKQRRIV-GIVIQMFFTLGI 249

  Fly   333 MVMPWIALSAGNWRRFSSFTSLPIVLAMFSFCLLPESARWLVSVGEIDKALEILKNVIEVNKKQV 397
            :::|.||....:|:......|||..|.:..:.::|||.|||::..:.:|||:||:.|.:.|.|.:
Mouse   250 IILPGIAYFTPSWQGIQLAISLPSFLFLLYYWVVPESPRWLITRKQGEKALQILRRVAKCNGKHL 314

  Fly   398 SKEILDLFEASCTQFYKEELDGRDFTVLSIFKRKRMARYMILMILIWMSISLVYDGHVRAASVLD 462
            |.   :..|.:.|.   ||:...  :.|.:.:..:|.:..::::..|.:.::||.|.|....::.
Mouse   315 SS---NYSEITVTD---EEVSNP--SCLDLVRTPQMRKCTLILMFAWFTSAVVYQGLVMRLGLIG 371

  Fly   463 SENIFLFFTIACATELPGNILVILTLDRAGRRWCSFFYTSLSGVFSLLGASFQNRANMRMSALA- 526
            . |:::.|.|:...||||.:|::||::|.|||........::||..|:.|..........:.:|
Mouse   372 G-NLYIDFFISGLVELPGALLILLTIERLGRRLPFAASNIVAGVSCLVTAFLPEGIPWLRTTVAT 435

  Fly   527 -GRFFSNICYNIGLQWAAEILPTVVRAQGVAFIHTMGFVAMLMSPPVVY-LSKKSLSSTLIVLGA 589
             ||....:.:.|.....:|:.||.:|..||:....:.....:::|.::: |:...|...||:.|.
Mouse   436 LGRLGITMAFEIVYLVNSELYPTTLRNFGVSLCSGLCDFGGIIAPFLLFRLAAIWLELPLIIFGI 500

  Fly   590 LGIFGGLLALFLPETLNHELPETLSDGAQFGKNQRIWHMPCCG 632
            |....|.|.:.||||....||||:.|..:.|.:|    :..||
Mouse   501 LASVCGGLVMLLPETKGIALPETVEDVEKLGSSQ----LHQCG 539

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10486	NP_647998.2	2A0119	104..612	CDD:273328	144/533 (27%)
		MFS	231..602	CDD:119392	102/377 (27%)
Slc22a3	NP_035525.1	2A0119	12..523	CDD:273328	144/533 (27%)
		MFS	145..513	CDD:119392	102/381 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167844079
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9N9
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.850