Protein Alignment CG10486 and Slc22a2

DIOPT Version :9

• Sequence 1: NP_647998.2
• Gene: CG10486 / 38664
• FlyBaseID: FBgn0035647
• Length: 706
• Species: Drosophila melanogaster
• Sequence 2: NP_038695.1
• Gene: Slc22a2 / 20518
• MGIID: 1335072
• Length: 553
• Species: Mus musculus
• Alignment Length: 562
• Identity: 143/562 - (25%)
• Similarity: 248/562 - (44%)
• Gaps: 54/562 - (9%)

  Fly    97 DDLLPMIGQFGRFQIRLFLFMIPFCFITAFVYLGQIFMCLTPPKYYCYVPELLH-------TPVE 154
            ||:|..||:|..||.:.|..:.........:|:|.:|:..| |.::|..|.:..       :|.|
Mouse     5 DDILEHIGEFHLFQKQTFFLLALLSGAFTPIYVGIVFLGFT-PNHHCRSPGVAELSQRCGWSPAE 68

  Fly   155 LRKELSIPKEKDGS------YSRCRMYNTNYTK---------IHFAENPSAYINTSLPTIPCKKG 204
               ||:......||      .|:|..|..::.:         ...|.|.|     .||..||:.|
Mouse    69 ---ELNYTVPGLGSAGEVSFLSQCMRYEVDWNQSTLDCVDPLSSLAANRS-----HLPLSPCEHG 125

  Fly   205 YVFEQEGRAFESATMEFGWLCDDDKYATYAQIIFFLGSILGGLAYGHFADHCGRVAALVSSCFLA 269
            :|::..|   .|...||..:|.........|.:..:|..:|.:..|:.||..||...|:.:..:.
Mouse   126 WVYDTPG---SSIVTEFNLVCAHSWMLDLFQSLVNVGFFIGAVGIGYLADRFGRKFCLLVTILIN 187

  Fly   270 LVGSLATSMSTDFFTFAISRFLVGASYDTCFTMVYILVLEYVGPKYRTLVANLSLALFYSPFTMV 334
            .:..:..::|.::....:.|||.|......:.:.|||:.|:||..||..| .:...:.::...::
Mouse   188 AISGVLMAISPNYAWMLVFRFLQGLVSKAGWLIGYILITEFVGLGYRRTV-GICYQIAFTVGLLI 251

  Fly   335 MPWIALSAGNWRRFSSFTSLPIVLAMFSFCLLPESARWLVSVGEIDKALEILKNVIEVNKKQVSK 399
            :..:|.:..|||......:||....:..|..:|||.|||:|..:..||::|:|::.:.|.|.|
Mouse   252 LAGVAYALPNWRWLQFAVTLPNFCFLLYFWCIPESPRWLISQNKNAKAMKIIKHIAKKNGKSV-- 314

  Fly   400 EILDLFEASCTQFYKEELDGRDF--TVLSIFKRKRMARYMILMILIWMSISLVYDGHVRAASVLD 462
                  ..|......:|..|...  :.|.:.:..::.::.::::..|.:.|::|.|.:.... |.
Mouse   315 ------PVSLQSLTADEDTGMKLNPSFLDLVRTPQIRKHTLILMYNWFTSSVLYQGLIMHMG-LA 372

  Fly   463 SENIFLFFTIACATELPGNILVILTLDRAGRRWCSFFYTSLSGVFSLLGASFQNRANMRMSALA- 526
            .:||:|.|..:...|.|...::|||:||.|||:.......::|...|......:........:|
Mouse   373 GDNIYLDFFYSALVEFPAAFIIILTIDRIGRRYPWAVSNMVAGAACLASVFIPDDLQWLKITVAC 437

  Fly   527 -GRFFSNICYNIGLQWAAEILPTVVRAQGVAFIHTMGFVAMLMSPPVVY-LSKKSLSSTLIVLGA 589
             ||....|.|.:.....||:.||.:|...|....:|..:..:::|.:|| |:...|...|:|...
Mouse   438 LGRMGITIAYEMVCLVNAELYPTYIRNLAVLVCSSMCDIGGIVTPFLVYRLTDIWLEFPLVVFAV 502

  Fly   590 LGIFGGLLALFLPETLNHELPETLSDGAQF-----GKNQRIW 626
            :|:..|.|.|.||||....||||:.|..:.     .|.:||:
Mouse   503 VGLVAGGLVLLLPETKGKALPETIEDAEKMQRPRKKKEKRIY 544

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10486	NP_647998.2	2A0119	104..612	CDD:273328	133/534 (25%)
		MFS	231..602	CDD:119392	92/375 (25%)
Slc22a2	NP_038695.1	2A0119	12..525	CDD:273328	133/534 (25%)
		MFS	125..492	CDD:119392	92/379 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167843835
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9N9
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.850