Protein Alignment CG10486 and Slc22a25

DIOPT Version :10

• Sequence 1: NP_647998.2
• Gene: CG10486 / 38664
• FlyBaseID: FBgn0035647
• Length: 706
• Species: Drosophila melanogaster
• Sequence 2: NP_620263.1
• Gene: Slc22a25 / 192273
• RGDID: 621104
• Length: 552
• Species: Rattus norvegicus
• Alignment Length: 554
• Identity: 160/554 - (28%)
• Similarity: 253/554 - (45%)
• Gaps: 43/554 - (7%)

  Fly    96 FDDLLPMIGQFGRFQIRLFLFMIPFCFITAFVYLGQIFMCLTPPKYYCYVPELLHTPVE------ 154
            |.|||..:|..|||||....|::.|..|.:...|.:.|..:. |.:.|:||.|.:..|.
  Rat     3 FQDLLNQVGSLGRFQILQMTFILIFNIIISPHSLLENFTAVI-PNHRCWVPILDNDTVSGNDNGN 66

  Fly   155 ------LRKELSIPKEKDGSYSRCRMY-NTNYTKIHFAENPSAYINTSLPTIPCKKGYVFEQEGR 212
                  ||  :|||.:.|....:||.: ...:..:|.  |.:....|...|.||..|:|::|.
  Rat    67 LSQDDLLR--VSIPLDSDLRPEKCRRFVQPQWDLLHL--NGTFSSVTEPDTEPCVDGWVYDQS-- 125

  Fly   213 AFESATM-EFGWLCDDDKYATYAQIIFFLGSILGGLAYGHFADHCGRVAALVSSCFLALVGSLAT 276
            .|.|..: |:..:|:.....:.|:.:|..|.::|.:.||...|..||...|:.:.....|.....
  Rat   126 TFLSTIITEWDLVCESQSLDSIAKFLFLTGILVGNILYGPLTDRFGRRLILICASLQMAVTETCA 190

  Fly   277 SMSTDFFTFAISRFLVGASYDTCFTMVYILVLEYVGPKYRTLVANLSLALFYSPFTMVMPWIALS 341
            :.:..|..:...|||.|.|:.|..|...:|::|:..||::.|...|.|.......| |:..:|.:
  Rat   191 AFAPTFLIYCSLRFLAGISFSTVLTNSALLIIEWTRPKFQALATGLLLCAGAIGQT-VLAGLAFT 254

  Fly   342 AGNWRRFSSFTSLPIVLAMFSFCLLPESARWLVSVGEIDKALEILKNVIEVNKKQVSKEILDLFE 406
            ..||.......|:||...:.....|.||||||:...::.|.|:.|..|..:|..:.|.::|.: |
  Rat   255 VRNWHHLHLAMSVPIFFLLVPTRWLSESARWLIMTNKLQKGLKELIKVAHINGMKNSTDVLTI-E 318

  Fly   407 ASCTQFYKEELDGRD--FTVLSIFK----RKRMARYMILMILIWMSI--SLVYDGHVRAASVLDS 463
            ...| ..||||:...  .::..:|:    |||:....::..::|:|:  .|:...|:|.
  Rat   319 VVRT-IMKEELEASQTKSSLWDLFRTPNLRKRICLLSLVRFVVWLSVIGLLINFQHLRI------ 376

  Fly   464 ENIFLFFTIACATELPGNILVILTLDRAGRRWCSFFYTSLSGVFSLLGASF--QNRANMRM-SAL 525
             |:||...:.....:|.|::.|..::..|||....|..||.|: |:|...|  |....:|| .|.
  Rat   377 -NVFLLQCLLGIITIPANLVGIFLVNHLGRRISQLFIISLFGI-SILAIIFVPQEMQILRMVLAT 439

  Fly   526 AGRFFSNICYNIGLQWAAEILPTVVRAQGVAFIHTMGFVAMLMSPPVVYLSKKSLSSTLIVLGAL 590
            .|..||.:..:..|..|.|:|||::||..:..|...|.....:||..:.|...|.|...|:.|.|
  Rat   440 FGGVFSFVSVSSALVHANELLPTIIRATALGVIGIAGSTGAALSPLFMILRTYSDSLPWIIYGVL 504

  Fly   591 GIFGGLLALFLPETLNHELPETLSDGAQFGKNQR 624
            ...|||:.|.||||.|..||:::.|....|:..|
  Rat   505 SFLGGLVVLLLPETKNQPLPDSIQDVENEGRASR 538

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10486	NP_647998.2	2A0119	104..612	CDD:273328	153/532 (29%)
Slc22a25	NP_620263.1	MFS_OAT	109..506	CDD:340932	115/409 (28%)