Protein Alignment CG10486 and F45E10.2

DIOPT Version :9

• Sequence 1: NP_647998.2
• Gene: CG10486 / 38664
• FlyBaseID: FBgn0035647
• Length: 706
• Species: Drosophila melanogaster
• Sequence 2: NP_001022174.1
• Gene: F45E10.2 / 185801
• WormBaseID: WBGene00009729
• Length: 538
• Species: Caenorhabditis elegans
• Alignment Length: 664
• Identity: 148/664 - (22%)
• Similarity: 256/664 - (38%)
• Gaps: 181/664 - (27%)

  Fly     1 MANDEKGNASTEDDDKPKKREHRDQGQQSKLKKIKYYIEPDKV----------------DIGIQA 49
            |:.||    |.||:|.|          |:....|..|...|.:                |||
 Worm     1 MSIDE----SLEDEDIP----------QTAQTTITSYCSSDVINSLNEAMNPLIEQGLKDIG--- 48

  Fly    50 GDSLEKVKVTYVEPDDEESSHGFFWGKKKSETSLPRRSWETDDYIDFDDLLPMIGQFGRF-QIRL 113
                .|.:..|||..|..                       :|.|..:.:...:|.|||| ||:.
 Worm    49 ----TKQEAHYVEEVDVR-----------------------NDKIKLESIFEGLGSFGRFQQIQF 86

  Fly   114 FLFMIPFCFITAFVYLGQIFMCLTPPKYYCYVPELLHTPVELRKELSIPKEKDGSYSRCRMYNTN 178
            .|..||..|::..| :...|: ::|.:..|                               ..||
 Worm    87 ILICIPIAFVSMHV-MSWTFV-VSPARKIC-------------------------------NETN 118

  Fly   179 YTKIHFAENPSAYINTSLPTIPCKKGYVFEQEGRAFESATMEFGWLCDDDKYATYAQIIFFLGSI 243
            .|:|...|. .||..:..          :|.:|        :.||:     .|| .|.::|:|.:
 Worm   119 ETRIDGCEE-LAYSASDR----------WEMDG--------DNGWI-----RAT-VQAVYFIGQM 158

  Fly   244 LGGLAYGHFADHCGRVAALVSSCFLALVGSLATSMSTDFFTFAISRFLVGASYDTCFTMVYILVL 308
            :|....|..||..||...|.....|.:|.:|...::..::.:||.:...|.:....:.:..:|.:
 Worm   159 IGSFTCGVMADKIGRKKVLFWCLVLQVVCALLLIVAPTWWIYAILKAGTGFTQPGIYGVAVVLGI 223

  Fly   309 EYVGPKYRTLVANLS--LALFYSPFTMVMPWIALSAGNWRRFSSFTSLPIVLAMFSFCLLPESAR 371
            |.||.|||:.:|.::  ..:.......||.:..:   ::|...:..::|.::.:..:.::.||||
 Worm   224 ELVGKKYRSFIAVIANVFGVIGGVLLAVMAYFIV---DYRLLHASIAIPSLIFITYYWMIHESAR 285

  Fly   372 WLVSVGEIDKALEILKNVIEVNKKQVSKEILDLFEASCTQFYKEELDGRDFTVLSIFKRKRMARY 436
            ||||..:.|.|..:|......|||.:.|...:..|........::.|  .|.|..:.:..:|.:.
 Worm   286 WLVSQEKYDDANVVLCATANWNKKTIPKNWAEKIEKKMDVTATKKKD--SFGVFDLIRTPQMRKR 348

  Fly   437 MILMILIWMSISLVYDGHVRAASVLDSENIFLFFTIACATELPGNILVILTLDRAGRRWCSFFYT 501
            .|...::|...:::|.| :...|.:...::|:.|..:...|||..|:|.|.:||.|||   ..|:
 Worm   349 TIANFVMWPVTTMMYYG-LTMRSDVGGGSLFVTFVTSQLMELPAVIIVALLIDRLGRR---IMYS 409

  Fly   502 SLSGVFS---LLGASF--------QNRANMRMSALAGRFFSNICYNIGLQWAAEILPTVVR---- 551
              ..:|:   ||.||:        |....|.|.|...   .::.|.:...:.:|:.|||:|
 Worm   410 --GAIFTAGMLLLASWLTHDLIPSQYAVIMLMVAKGA---VSVAYTVMYTYTSELFPTVIRNTAV 469

  Fly   552 -------------AQGVAF--IHTMGFVAMLMSPPVVYLSKKSLSSTLIVLGALGIFGGLLALFL 601
                         |..:||  :...|.:.|::...::.|....:|.|:                |
 Worm   470 GCCSTIARFGAISASFIAFFLVDRFGRIVMIIPFTILALCASIVSWTM----------------L 518

  Fly   602 PETLNHELPETLSD 615
            |||:|.:||:::|:
 Worm   519 PETVNQQLPDSISE 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10486	NP_647998.2	2A0119	104..612	CDD:273328	125/540 (23%)
		MFS	231..602	CDD:119392	92/402 (23%)
F45E10.2	NP_001022174.1	MFS_SLC22	121..518	CDD:340875	100/451 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.010