DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10486 and suex-2

DIOPT Version :9

Sequence 1:	NP_647998.2	Gene:	CG10486 / 38664	FlyBaseID:	FBgn0035647	Length:	706	Species:	Drosophila melanogaster
Sequence 2:	NP_501556.2	Gene:	suex-2 / 183742	WormBaseID:	WBGene00008271	Length:	502	Species:	Caenorhabditis elegans

Alignment Length:	550	Identity:	110/550 - (20%)
Similarity:	194/550 - (35%)	Gaps:	171/550 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   113 LFLFMIPFCFITAFVYLGQIFMCLTPPKY-----YCYVPELLHTPVELRKELSIPKEKDGSYSRC 172
            :.|:.|...|....:::  ||:...|..|     :||..:                      |:|
Worm    12 MVLYQITLIFSAQLIFV--IFLDFMPSTYCTDDNFCYKLQ----------------------SKC 52

  Fly   173 RM---YNT-NYTKIHFAENPSAYINTSLPTIPCKKGYVFEQEGRAFESATMEFGWLC---DDDKY 230
            .|   :|. |...::..||.|          .|    :.:.....|.||..|:...|   :....
Worm    53 LMDYDHNAQNLCPVNMTENAS----------KC----IADHSRLFFRSAQFEYQQDCTGLNGFSL 103

  Fly   231 ATYAQIIFFLGSILGGLAYGHFADHCGRVAALVSSCFLALVGSLATSMSTDFFTFAISRFLVGAS 295
            :|..    |:|::||.:|.|..||..||....:||....:...:.::..|:.::|.|.|.|:|.|
Worm   104 STAT----FIGTLLGNIALGFLADKYGRRTIYLSSLLFGIPCVVLSAAITNIYSFYIFRILIGIS 164

  Fly   296 YDTCFTMVYILVLEYVGPKYRTLVANLSLALFYSP-FTMVMPWIALSAGNWRRFS------SFTS 353
            .....|:.:....|.:.|..|..:    ||....| ..|:...:|..:..|:..:      |..|
Worm   165 VSGTLTVGWTYATEMISPNRRLRI----LAFSNWPNARMIQVGLAYISQEWKTATYICAAVSCLS 225

  Fly   354 LPIVLAMFSFCLLPESARWLVSVGEIDKALEILKNVIEVNKKQVSKEILDLFEASCTQFYKEE-- 416
            |||::      .||||..||....:...|.:..|.:.::.|                 ||..|
Worm   226 LPILI------YLPESPIWLDQKQKYKNASKARKRLRKIGK-----------------FYSNEHS 267

  Fly   417 --LDGRDFTVLSIFKRKRMARYMILMILIWMSISL-VYDGHVRAASVLDSENIFL---------- 468
              :..|.||...|.|..::.....::|.::..:.| ||...:..|.:  ::|::|
Worm   268 TVVANRKFTPTRILKDPKLRNSFFMIIFMYFYVGLAVYITDLNGADM--TKNLYLGQFLSGLVLS 330

  Fly   469 --------------------FFTIA---------CATELPGNILVILTLDRAGRRWCSFFYTSLS 504
                                .|.||         |       ||:.|.|:..|    ||.|.|
Worm   331 IAQFIIGMTEPYLTGLGRRVLFLIAQFIAMLCYIC-------ILICLYLNWKG----SFLYLS-- 382

  Fly   505 GVFSLLGASFQNRANMRMSALAGRFFSNICYNIGLQWAAEILPTVVRAQGVAFIH---TMGFVAM 566
             .::|..|:                 .::|.........|::||.|||...:..:   .:|.:..
Worm   383 -AYTLAYAT-----------------QSLCLEAAYLSLVELMPTDVRATAGSTANICMKIGTILA 429

  Fly   567 LMSPPVVYLSKKSL---SSTLIVLGALGIF 593
            .::.|:.:..:.||   :.::..:|.:.:|
Worm   430 TLTKPLKFAYEPSLFFINLSICTIGMILVF 459

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10486	NP_647998.2	2A0119	104..612	CDD:273328	109/549 (20%)
CG10486	NP_647998.2	MFS	231..602	CDD:119392	86/419 (21%)
suex-2	NP_501556.2	MFS	108..460	CDD:391944	85/411 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910