Protein Alignment CG10486 and C06H5.6

DIOPT Version :9

• Sequence 1: NP_647998.2
• Gene: CG10486 / 38664
• FlyBaseID: FBgn0035647
• Length: 706
• Species: Drosophila melanogaster
• Sequence 2: NP_507509.3
• Gene: C06H5.6 / 180170
• WormBaseID: WBGene00007394
• Length: 556
• Species: Caenorhabditis elegans
• Alignment Length: 660
• Identity: 138/660 - (20%)
• Similarity: 255/660 - (38%)
• Gaps: 151/660 - (22%)

  Fly    64 DDEESSHGFFWGKKKSETSLPRRS---WETDDY--IDFDDLLPMIGQFGRFQIRLFLFMIPFCFI 123
            |:..|||             |.||   ..|.:|  :|.|.:|...|::||:|      |:.:...
 Worm     3 DEPSSSH-------------PPRSNSMSATFNYLHLDADKVLTAFGKYGRYQ------MLAYVIT 48

  Fly   124 TAFVYLGQIFMCLTPPKYYCYVPELLHTPVELRKELSIPKEKDGSY------SRCRMYNT--NYT 180
            |:...|..:.|.:.|         .:...||...:|..|:..|.::      ..|.:.:|  |.|
 Worm    49 TSVHMLFALNMMIMP---------FITKSVEFLCDLPDPESIDSAHFSPLVGDSCHLQDTQLNIT 104

  Fly   181 KIHFAENPSAYINTSLPTIPCKKGYVFEQEGRAFESATMEFGWLCDDDKYATYAQIIFFLGSILG 245
            ....|.|.::|            .|:.:::    .:.|.:|..:|:....|.:|..||.:|.::.
 Worm   105 IDCLAVNGASY------------NYLADKK----STITSDFDLVCEYQGMAEHATSIFLVGGMIV 153

  Fly   246 GLAYGHFADHCGRVAALVSSCFLALVGSLATSMSTDFFTFAISRFLVGASYDTCFTMV-YILVLE 309
            .......:|..||....:...::::..:|..:.:.::..|.:.||:.|.: .|.|:|. ::|.:|
 Worm   154 SPFVSQLSDILGRRPLFLIPLYISVAANLICAAAPNYLIFLLFRFISGVA-TTSFSMTGFVLCME 217

  Fly   310 YVGPKYRTLVANLSLALFYSPFTMVMPWIA--LSAG-------NWRRFSSFTSLPIVLAMFSFCL 365
            .|..::|:|:          |....:.|:.  :.||       |||......|:|.:|.:..|..
 Worm   218 SVSLEFRSLI----------PVLTTISWVGGYMLAGVFYVFFKNWRVLYFAASVPGLLTIPFFWF 272

  Fly   366 LPESARWLVSVGEIDKALEILKNVIEVNKKQVSKEILDLFEASCTQFYKEELDGRDFTVLSIFKR 430
            .|||..||::.....|..:.:...:..||:.:|  ::|     |...  :.:|....|..:...|
 Worm   273 TPESLHWLMTKQNDRKIKKYINESVAFNKQTIS--LID-----CRNI--QTVDNAPATTKTRTFR 328

  Fly   431 KRMARYMILMILIWMSISLVYDGHVRAASVLD---SENIFLFFTIACATELPGNILVILTLDRAG 492
            ......:.:.::|...|.:|..|...|.|:..   ||:....:.::...|||...|.:..|....
 Worm   329 ALFYPKIFVHVVINSFILIVMSGTYWALSLYSTELSEDETTGYFLSGLVELPAGFLSVFLLIAFK 393

  Fly   493 RRWCSFFYTSLSGVFSLLGASFQNRANMRM-SALAGRFFSNICYNIGLQWA------AEILPTVV 550
            |:..||:..:.:.||.|.......:.|.:| ..|..:..::|.      ||      :|..||.:
 Worm   394 RKTVSFYSLAFTAVFMLCTVYIPMQGNYKMIFPLLAKSTNSIV------WASQPLLYSEATPTTI 452

  Fly   551 R---AQGVAFIHTMGFVAMLMSPPVVYLSKKSLSSTLIVLGALGIFGGLLALFLPETLNHELPET 612
            |   :..|:|:..:|.:.   :|.:..|:..:..:..|::..:.|....|.|..|||.|.:|||.
 Worm   453 RNVFSGVVSFVGELGSIG---APYMNRLTAINQDAPAILISIMSIVAAFLVLLQPETKNKKLPED 514

  Fly   613 LSDGAQFGKNQRIWHMPCCGPGSRKSHPRHNWHQGSSLRTLSKDEFRSSKMYRKTKYRFESHPSP 677
            |                                          |:|.:..::|..|.:.:...|.
 Worm   515 L------------------------------------------DQFDAGPLFRGWKKQKDLEASE 537

  Fly   678 SSSDYKGTEE 687
            :|.:.|..||
 Worm   538 ASEEVKEKEE 547

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10486	NP_647998.2	2A0119	104..612	CDD:273328	115/538 (21%)
		MFS	231..602	CDD:119392	84/393 (21%)
C06H5.6	NP_507509.3	MFS_SLC22	115..504	CDD:340875	89/433 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	5.010