Protein Alignment CG10486 and F23F12.3

DIOPT Version :10

• Sequence 1: NP_647998.2
• Gene: CG10486 / 38664
• FlyBaseID: FBgn0035647
• Length: 706
• Species: Drosophila melanogaster
• Sequence 2: NP_498433.3
• Gene: F23F12.3 / 175926
• WormBaseID: WBGene00017751
• Length: 507
• Species: Caenorhabditis elegans
• Alignment Length: 571
• Identity: 128/571 - (22%)
• Similarity: 216/571 - (37%)
• Gaps: 167/571 - (29%)

  Fly   108 RFQIRLFLFMIPFCFITAFVYLGQIFMC-LTPPKYYCYVPELLHTPVELRKELSIPKEKDG---S 168
            ||.|..|       |:..|   |..:.| |..|.:|.:.|             .:..|..|   |
 Worm     8 RFHILCF-------FLWQF---GLFYACQLIFPIFYNFHP-------------GLSCEDPGFNFS 49

  Fly   169 YSRCRMYNTNYTKIHFAENPSAYINTSLPTIPCKKGYVFEQEGRAFESATMEFGWLCDDDKY-AT 232
            ..:|::     :|:.        |.|.| |..|.|.::   |...|.|...:|...|....| :.
 Worm    50 KPKCKL-----SKVE--------ICTEL-TANCSKWHI---EPAPFHSMVQDFKMFCGTKAYDSA 97

  Fly   233 YAQIIFFLGSILGGLAYGHFADHCGRVAALVSSCFLALVGSLATSMSTDFFTFAISRFLVGASYD 297
            :...|.|:|:::|.|.|||..||.||.........:.::..:|:..:..:..||:..|:.|.|..
 Worm    98 WIATIQFIGALVGALVYGHLGDHFGRKPVSFVGISIGIIFGVASGFAPSWEVFAVLLFICGTSVA 162

  Fly   298 TCFTMVYILVLEYVGPKYRTLVANLSLALFYS------PFTMVMPWIALSAGNWRRFSSFTS--- 353
            ....:.|..:||::.|:.|..     |..|::      .||:|    ....|.||..:..||
 Worm   163 CIMIVFYAYILEFIEPEQRVF-----LRTFFNWGYARLVFTLV----CFICGYWRSAAIATSLLA 218

  Fly   354 ---LPIVLAMFSFCLLPESARWLVS------VGEIDKALEILKNVIEVNKKQVSKEILDLFEASC 409
               ||::|      .||||.:|..:      :.|.:|.:..|..:..|.::....|.:
 Worm   219 LPILPVLL------WLPESPKWYATKNRFQEMKEAEKKISWLSGISYVEREDRRTEKI------- 270

  Fly   410 TQFYKEELDGRDFTVLSIFKRKRMARYMILMILIWMSISLVYDG----------------HVRAA 458
                 ||.|.:.:|:..:|....:|...|::..:|.|.|:...|                .|:||
 Worm   271 -----EEKDTKVYTIRDLFSSWPIAYSTIVVGSLWFSTSVSSFGADLNSGNLAGNFYLSQFVQAA 330

  Fly   459 SV-LDSENIFL------------------FFTIACATELPGNILVILTLD----RAGRRWCSFFY 500
            :: |...:|||                  ...|||.|.:   :.::::.|    ..|.|..:..
 Worm   331 AIALSKLSIFLLDLFIPSFNRQRLHQVPQIIMIACYTTI---MALMISPDSDCSSQGSRNLAII- 391

  Fly   501 TSLSGVFSLLGASFQNRANMRMSALAGRFFSNICYNIGLQW------AAEILPTVVRAQGVAFIH 559
                 :.:::|.||                      |.|.|      ||||.||.:|..|:....
 Worm   392 -----IINIIGTSF----------------------IELTWDACYLVAAEIFPTRIRTIGIGTCS 429

  Fly   560 TMGFVAMLMSPPVVYLSKKSLSSTLIVLGALGIFGGLLA-LFLPETLNHEL 609
            .:..:..|::|.:.|||:.......|::.::||...|:: .|||:|...:|
 Worm   430 LLARIGALLAPQMAYLSEIYPPIPYIIVCSIGIISLLISCFFLPDTKGVDL 480

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10486	NP_647998.2	2A0119	104..612	CDD:273328	128/571 (22%)
F23F12.3	NP_498433.3	MFS_SLC22	70..472	CDD:340875	101/462 (22%)