DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10486 and UST4r

DIOPT Version :9

Sequence 1:	NP_647998.2	Gene:	CG10486 / 38664	FlyBaseID:	FBgn0035647	Length:	706	Species:	Drosophila melanogaster
Sequence 2:	NP_599206.2	Gene:	UST4r / 171397	RGDID:	620976	Length:	552	Species:	Rattus norvegicus

Alignment Length:	568	Identity:	141/568 - (24%)
Similarity:	238/568 - (41%)	Gaps:	71/568 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    96 FDDLLPMIGQFGRFQIRLFLFMIPFCFITAFVYLGQIFM---CLTPPKYYCYVPELLHTPVE--- 154
            |.:||..:|..|||||...:|::    .|:.:.:..|.:   ....|.:.|:||.|.:..|.
  Rat     3 FQELLNQVGGLGRFQILQMVFVV----FTSVIVVPHIIIENFTAAIPSHRCWVPILDNVTVSDND 63

  Fly   155 ---LRKE----LSIPKEKDGSYSRCRMY----------NTNYTKIHFAENPSAYINTSLPTIPCK 202
               |.::    :|||.:......:||.:          |..::.|           |...|.||.
  Rat    64 SRILNQDKLLKISIPLDSHLRLDKCRRFAQPQWHLLDLNDTFSSI-----------TEPDTEPCV 117

  Fly   203 KGYVFEQEGRAFESATM-EFGWLCDDDKYATYAQIIFFLGSILGGLAYGHFADHCGRVAALVSSC 266
            .|:|:::..  |.|.|: |:..:|:.....:..::.|.:|:.:||:..|..:|..||...|..:.
  Rat   118 DGWVYDRSN--FHSTTVTEWNLVCESQALNSVTKLSFMIGAFIGGIVNGLLSDRFGRKFILKYAL 180

  Fly   267 FLALVGSLATSMSTDFFTFAISRFLVGASYDTCFTMVYILVLEYVGPKYRTLVANL-SLALFYSP 330
            ....:.......:.:.|.:...|||.|.|.:.....:.:|:.|:..||:.|:|..| |.|..:.
  Rat   181 LQMAITETCAGFAPNLFIYCSLRFLAGMSLEPITVNINLLMFEWTSPKFLTMVTVLGSCAGSFG- 244

  Fly   331 FTMVMPWIALSAGNWRRFSSFTSLPIVLAMFSFCLLPESARWLVSVGEIDKALEILKNVIEVN-- 393
             .|::..:|....||.......|:||...:.....|.||||||:.:.:..|.|:.||.|..:|
  Rat   245 -GMILAGLAFQFQNWHHLQLAMSVPIFFFLILTRWLSESARWLIVINKPQKGLKELKKVAHINGM 308

  Fly   394 KKQVSKEILDLFEASCTQFYKEELDG-------RDFTVLSIFKRKRMARYMILMILIWMSISLVY 451
            ||......:::...|    .|:||:.       ||.....|.:::       :.||.::.:..:.
  Rat   309 KKSGDNITMEVVRTS----MKKELEAAKMRPSPRDLFHTPILRKQ-------IYILSFIRLLFIL 362

  Fly   452 DGHVRAASVLD--SENIFLFFTIACATELPGNILVILTLDRAGRRWCSFFYTSLSGVFSLLGASF 514
            .| |..|..|.  |.||.|...:...:.:..:::....|:..|||........|.|: |:|.|.|
  Rat   363 SG-VGVAIHLQHLSNNIELLQILISVSSILFSVIGHFVLNHIGRRITQMVIMFLRGI-SILTAIF 425

  Fly   515 --QNRANMR-MSALAGRFFSNICYNIGLQWAAEILPTVVRAQGVAFIHTMGFVAMLMSPPVVYLS 576
              |....:| :.|:.....:.:.|......|.|:|||.:||.....|...|.:...::|..:.|:
  Rat   426 APQEMETLRFIMAMMAEGLAALSYAANSLHANELLPTTLRATARGVIGMFGNIGFFLAPLCMMLA 490

  Fly   577 KKSLSSTLIVLGALGIFGGLLALFLPETLNHELPETLSDGAQFGKNQR 624
            ..|.:...|..|...|..|.:.|.||||.|:.||:...|.....|..|
  Rat   491 SYSPNLPWIFYGGFAILSGFIVLLLPETKNNPLPDCTHDVENDWKESR 538

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10486	NP_647998.2	2A0119	104..612	CDD:273328	135/546 (25%)
CG10486	NP_647998.2	MFS	231..602	CDD:119392	94/385 (24%)
UST4r	NP_599206.2	MFS_OAT	109..516	CDD:340932	105/423 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166347348
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.940