Protein Alignment CG10486 and SLC22A9

DIOPT Version :9

• Sequence 1: NP_647998.2
• Gene: CG10486 / 38664
• FlyBaseID: FBgn0035647
• Length: 706
• Species: Drosophila melanogaster
• Sequence 2: NP_543142.2
• Gene: SLC22A9 / 114571
• HGNCID: 16261
• Length: 553
• Species: Homo sapiens
• Alignment Length: 573
• Identity: 143/573 - (24%)
• Similarity: 238/573 - (41%)
• Gaps: 84/573 - (14%)

  Fly    96 FDDLLPMIGQFGRFQIRLFLFMIPFCFITAFVYLGQIFMCLTPPKYYCYVPELLHTPVE------ 154
            |.|||...|...||||...:|:..|...|...::.:.|.... |.:.|:|..|.:..|.
Human     3 FQDLLGHAGDLWRFQILQTVFLSIFAVATYLHFMLENFTAFI-PGHRCWVHILDNDTVSDNDTGA 66

  Fly   155 ------LRKELSIPKEKDGSYSRCRMY-NTNYTKIHFAENPSAYINTSLPTI-PCKKGYVFEQEG 211
                  ||  :|||.:.:....:||.: :..:..:|.   ...:.|||...: ||..|:|::
Human    67 LSQDALLR--ISIPLDSNMRPEKCRRFVHPQWQLLHL---NGTFPNTSDADMEPCVDGWVYD--- 123

  Fly   212 RAFESATMEFGW--LCDDDKYATYAQIIFFLGSILGGLAYGHFADHCGRVAALVSSCFL--ALVG 272
            |...|:|:...|  :||.....:.|:.:|..|.::||:..||.:|..|| ..::..|:|  |:||
Human   124 RISFSSTIVTEWDLVCDSQSLTSVAKFVFMAGMMVGGILGGHLSDRFGR-RFVLRWCYLQVAIVG 187

  Fly   273 SLATSMSTDFFTFAISRFLVGASYDTCFTMVYILVLEYVGPKYRTLVANLSLALFYSPFTMVMPW 337
            :.| :::..|..:...|||.|.:..:..|...:|:.|:...:::.:...|.:......| |.:..
Human   188 TCA-ALAPTFLIYCSLRFLSGIAAMSLITNTIMLIAEWATHRFQAMGITLGMCPSGIAF-MTLAG 250

  Fly   338 IALSAGNWRRFSSFTSLPIVLAMFSFCLLPESARWLV-------SVGEIDKA------------- 382
            :|.:..:|.......|:|..:...:...|.||||||:       .:.|:.||
Human   251 LAFAIRDWHILQLVVSVPYFVIFLTSSWLLESARWLIINNKPEEGLKELRKAAHRSGMKNARDTL 315

  Fly   383 -LEILKNVI--EVNKKQVSKEILDLFEASCTQFYKEELDGRDFTVLSIFKRKRMARYMILMILIW 444
             |||||:.:  |:...|..|..|      |...:...:..|    :|:....|.|.:|     .:
Human   316 TLEILKSTMKKELEAAQKKKPSL------CEMLHMPNICKR----ISLLSFTRFANFM-----AY 365

  Fly   445 MSISLVYDGHVRAASVLDSENIFLFFTIACATELPGNILVILTLDRAGRRWCSFFYTSLSGVFSL 509
            ..::|    ||:..    ..|:||..|:..|..|..|.:....|....||........|..: .|
Human   366 FGLNL----HVQHL----GNNVFLLQTLFGAVILLANCVAPWALKYMNRRASQMLLMFLLAI-CL 421

  Fly   510 LGASF--QNRANMR-MSALAGRFFSNICYNIGLQWAAEILPTVVRAQGVAFIHTMGFVAMLMSPP 571
            |...|  |....:| :.|..|...|.:...:......|::||::||:.:....|...:|..::|.
Human   422 LAIIFVPQEMQTLREVLATLGLGASALANTLAFAHGNEVIPTIIRARAMGINATFANIAGALAPL 486

  Fly   572 VVYLSKKSLSSTLIVLGALGIFGGLLALFLPETLNHELPETLSDGAQFGKNQR 624
            ::.||..|.....|:.|......|...|.||||.|..|.:|:.|    .||:|
Human   487 MMILSVYSPPLPWIIYGVFPFISGFAFLLLPETRNKPLFDTIQD----EKNER 535

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10486	NP_647998.2	2A0119	104..612	CDD:273328	134/551 (24%)
		MFS	231..602	CDD:119392	93/398 (23%)
SLC22A9	NP_543142.2	Sugar_tr	11..527	CDD:331684	134/551 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	528..553		4/12 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153774
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.940