DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10486 and LOC100490946

DIOPT Version :9

Sequence 1:	NP_647998.2	Gene:	CG10486 / 38664	FlyBaseID:	FBgn0035647	Length:	706	Species:	Drosophila melanogaster
Sequence 2:	XP_031756488.1	Gene:	LOC100490946 / 100490946	-ID:	-	Length:	517	Species:	Xenopus tropicalis

Alignment Length:	540	Identity:	135/540 - (25%)
Similarity:	230/540 - (42%)	Gaps:	73/540 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    94 IDFDDLLPMIGQFGRFQ-IRLFLFMIPFCFITAFVYLGQIFMCLTPPKYYCYVPELLHTPVELRK 157
            :|.|.|      |..|| |.:.|...|.||:....:: .:|....|| |.|            |.
Frog     8 LDKDSL------FSPFQAIMVTLLSAPLCFVGTHNFM-PVFAAAVPP-YNC------------RS 52

  Fly   158 ELSIPKEKDGSYSRCRMYNTNYTKIHFAENP-SAYINT-SLPTIPCKKGYVFEQEGRAFESATM- 219
            .:::.:.:                  :.|:| :.|::: |..|.||::|:  |.:...|.|..:
Frog    53 NMTMDQPR------------------YPEDPCTQYVSSLSNSTKPCEEGW--EYDHSIFTSTIIS 97

  Fly   220 EFGWLCDDDKYATYAQIIFFLGSILGGLAYGHFADHCGRVAALVSSCFLALVG-SLATSMSTDFF 283
            |:..:||.......||.::..|.::|...||..||..||.|.::.| .|.:.| .:..::|.:..
Frog    98 EWDLVCDRQTLKEVAQSVYMAGVLVGAAVYGALADRFGRRAMILCS-LLQIAGMGIGVALSPNII 161

  Fly   284 TFAISRFLVGASYDTCFTMVYILVLEYVGPKYRTLVANLSLALFYSPFTMVMPWIALSAGNWRRF 348
            .:.:.|||.|............|.:|:...:||.:|:.:. ....:...:::..:|.:...||..
Frog   162 VYCLFRFLTGMGICGLIINDLGLAMEWTPRRYRPIVSMIQ-GYGLTCGAIILVGLAYAIRGWRWL 225

  Fly   349 SSFTSLPIVLAMFSFCLLPESARWLVSVGEIDKALEILKNVIEVNKKQ----VSKEILDLFEASC 409
            ....|||..:.....|.:|||||||......::||..|..|.::|.::    ::.|:|.|.:...
Frog   226 QLTASLPYFIFFLLMCWVPESARWLSLKKHSNQALANLNRVAKINGRKEGGPITLEMLKLDDQHS 290

  Fly   410 TQFYKEELDGRDFTVLSIFKRKRMARYMILMILIWMSISLVYDGHVRAASVLDSENIFLFFT--I 472
            |:....:|     |.|.:|:...|....:::.|.|.|.|.   |....|..:|...:.|:.|  :
Frog   291 TKAMTTKL-----TPLDLFRTPTMRTITLILSLSWFSSSF---GFFAIALDVDRFGLSLYLTQGV 347

  Fly   473 ACATELPGNILVILTLDRAGRRWCSFFYTSLSGVFSLLGASFQN---RANMRMSALAGRFFSNIC 534
            ...:|||..||..:|....|||....|....:|...|...:...   ...|.::.||.....: |
Frog   348 FAGSELPIRILATITAFYIGRRLTISFLLIFAGTLLLCTMAVPKDMLLLQMILTVLAKASLGS-C 411

  Fly   535 YNIGLQWAAEILPTVVRAQGVAFIHTMGFVAMLMSPPV----VYLSKKSLSSTLIVLGALGIFGG 595
            ......:.||:.|||:|..|:.|.:.|..:..::||.|    ||:|    ...:::...:.|..|
Frog   412 IVCSYLYTAEVYPTVLRQTGLGFTNMMMRLGAIISPLVMITRVYVS----FLPMVIFAVMPIISG 472

  Fly   596 LLALFLPETLNHELPETLSD 615
            |..|.||||||..|.:|:.:
Frog   473 LPILLLPETLNCPLMDTVEE 492

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10486	NP_647998.2	2A0119	104..612	CDD:273328	131/525 (25%)
CG10486	NP_647998.2	MFS	231..602	CDD:119392	96/384 (25%)
LOC100490946	XP_031756488.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.000