Protein Alignment CG10486 and slc22a20

DIOPT Version :10

• Sequence 1: NP_647998.2
• Gene: CG10486 / 38664
• FlyBaseID: FBgn0035647
• Length: 706
• Species: Drosophila melanogaster
• Sequence 2: XP_004913725.1
• Gene: slc22a20 / 100489586
• XenbaseID: XB-GENE-6463910
• Length: 572
• Species: Xenopus tropicalis
• Alignment Length: 621
• Identity: 161/621 - (25%)
• Similarity: 261/621 - (42%)
• Gaps: 99/621 - (15%)

  Fly    96 FDDLLPMIGQFGRFQ-IRLFLFMIPFCFITAFVYLGQIFMCLTPPKYYCYVPEL---------LH 150
            |:|||..:|..|||| |...:.:||..|:....:| |.|.... |.:.|:||.|         .|
 Frog     3 FNDLLLSVGGLGRFQIIHTTMLLIPMLFMGCHNFL-QNFSAAV-PAHRCWVPSLDNNTMGYDQDH 65

  Fly   151 TPVELRKELSIPKEKDGSYSRCRMYN-------TNYTKIHFAENPSAYINTSLPTIPCKKGYVFE 208
            .|.      .||.::......|..|.       ||.|..:..|             ||:.|:|::
 Frog    66 LPA------FIPMDESEKPLSCLRYRKALHSMWTNGTSTNHTE-------------PCEDGWVYD 111

  Fly   209 QEGRAFESATM-EFGWLCDDDKYATYAQIIFFLGSILGGLAYGHFADHCGRVAALVSSCFLALVG 272
            :..  |.|..: |:..:|...|....||.|:..|.::|.:..|..:|..||.|.|:.|..:..|.
 Frog   112 KSD--FSSTIVTEWDLVCKLRKMRQIAQSIYMAGVLVGAVLLGGLSDRLGRRALLIGSNLVMAVC 174

  Fly   273 SLATSMSTDFFTFAISRFLVGASYDTCFTMVYILVLEYVGPKYRTLVANLSLALFYSPFT---MV 334
            ....:...:|.|:...|.|.|.::.........|:||:..||.||::.    .||.:.||   ::
 Frog   175 GTCAAFLPNFITYCTFRCLCGIAFSGITLNTNSLILEWTPPKGRTIMG----TLFAAGFTCGQIL 235

  Fly   335 MPWIALSAGNWRRFSSFTSLPIVLAMFSFCLLPESARWLVSVGEIDKALEILKNVIEVNKKQVSK 399
            :..:|.....||......|.|.........|:|||||||:..|...:||:.|:.|..:|.|:  :
 Frog   236 LAALAYGIREWRWLQFAVSAPFYFFFLYSWLVPESARWLILKGRSHEALKALQRVAIINGKR--E 298

  Fly   400 EILDLFEASCTQFYKEELD--GRDFTVLSIFKRKRMARYMILMILIWMSISLVYDGHVRAASVLD 462
            |...|.|.......:.||:  .|..::..:|:...|.:..|.::::|.|..:.:.|     ..:|
 Frog   299 EGQKLSEMILISHMQSELNQVKRPHSLFDLFRTPGMRKVTICLMMVWFSSGVAFYG-----LGMD 358

  Fly   463 SEN----IFLF-FTIACATELPGNILVILTLDRAGRRWCSFFYTSLSGVFSLLGASF--QNRANM 520
            .:|    |||. ||.. |.::|..::..|.:...|||........|||| :||..:|  |....:
 Frog   359 LQNFGISIFLLQFTFG-AIDMPAKVVAALLMTYMGRRVTQATVLILSGV-ALLTNAFIPQGMKIL 421

  Fly   521 RM-SALAGRFFSNICYNIGLQWAAEILPTVVRAQGVAFIHTMGFVAMLMSPPVVYLSKKSLSSTL 584
            || .|:.|:......:.....::.|:.|||:|..|:..:..|..|..:::|.|:.|.:.|.....
 Frog   422 RMVLAVFGKGCMAASFACAYLFSGELFPTVIRQTGMGVVAMMARVGSVVAPLVLLLWEISPILPS 486

  Fly   585 IVLGALGIFGGLLALFLPETLNHELPETLSDGAQFGKNQRIWHMPCCGPGSRKSHPRHNWHQGSS 649
            .:.|...|..|..|.||.||.|.:|||::.:                  ...:|..:|      :
 Frog   487 AIYGIAAIIAGGAATFLMETNNQQLPESVEE------------------VEARSQGKH------T 527

  Fly   650 LRTLSKDEF-----RSSKMYRKTKY---RFESHPSP 677
            |:.:.|:|.     .|..|..|.:.   :.:||.:|
 Frog   528 LKKVLKEEVPLNQCESQNMAPKEEMPLNQSQSHSAP 563

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10486	NP_647998.2	2A0119	104..612	CDD:273328	145/538 (27%)
slc22a20	XP_004913725.1	MFS	101..485	CDD:475125	108/411 (26%)