DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10486 and zmp:0000001102

DIOPT Version :9

Sequence 1:	NP_647998.2	Gene:	CG10486 / 38664	FlyBaseID:	FBgn0035647	Length:	706	Species:	Drosophila melanogaster
Sequence 2:	XP_001340340.6	Gene:	zmp:0000001102 / 100000058	ZFINID:	ZDB-GENE-140106-62	Length:	560	Species:	Danio rerio

Alignment Length:	547	Identity:	143/547 - (26%)
Similarity:	253/547 - (46%)	Gaps:	57/547 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    96 FDDLLPMIGQFGRFQIRL-FLFMIPFCFITAFVYLGQIFMCLTPPKYYCYVPE-----LLHTPVE 154
            ||::|.....|||:||.| .|..||...|.....|......:  |.::|.:..     |.:...:
Zfish    13 FDNILDETDGFGRYQIALVMLLFIPRITIPCHFLLNNFIAAI--PSHHCDISSLDADGLGNLTQK 75

  Fly   155 LRKELSIPKEKDGSYSRCRMYNTNYTKIHFAENPSAYINTSLPTIPCKKGYVFEQEGRAFESATM 219
            .|..:|:|.::||:.:.|.|:  .:.:.....|.|:  :::||.:.|:.|:.|:........||
Zfish    76 ERLIVSVPAQEDGTPASCHMF--AHPQFQLLINSSS--SSALPVVECQNGWHFDNSTFISTLAT- 135

  Fly   220 EFGWLCDDDKYATYAQIIFFLGSILGGLAYGHFADHCGRVAALVSSCFLALVGSLATSMSTDFFT 284
            :|..:||....|..:..|||:|.:.|.:.:|...|..||.:.|:.|...::|.|:.::.|:.:..
Zfish   136 QFDLVCDKRGLAKASATIFFVGVMCGAVFFGVLCDKYGRRSMLLVSYVFSIVFSVTSAFSSSYIM 200

  Fly   285 FAISRFLVGASYDTCFTMVYILVLEYVGPKYRTLVANLSLALFYSPFTMVMPWIALSAGNWRRFS 349
            ||..|||.|.:......:..:|.:|:|..|:||.: .|..::.:|...|::...|....:||...
Zfish   201 FAAFRFLTGLALTGISNISVVLSIEWVDTKHRTFM-GLFGSMSWSIGNMLLAGFAFMVTDWRLLI 264

  Fly   350 SFTSLPIVLAMFSFCLLPESARWLVSVGEIDKALEILKNVIEVNKK-----QVSKEILDLFEASC 409
            ...:.|:.||..::..:|:|||||::.|:.:.|.:.|......||:     :|..|.|
Zfish   265 VIVTAPLFLATATWWWIPDSARWLIANGKTETAYKYLHKCATFNKRLDFTSRVKPETL------- 322

  Fly   410 TQFYKEELDGRDFTVLSIFKRKRMARYMILMILIWMSISLVYDGHVRAASVLDSENI-------F 467
            :.....:..|..:|.|.:.|..::.:..:...::|..::..|.|        .|.||       :
Zfish   323 STVVTVDHRGHSYTYLDLVKTPQLRKLTLFTGIVWYGVASTYYG--------ISLNITGFGLDPY 379

  Fly   468 LFFTIACATELPGNILVILTLDRAGRRWCSFFYTSLSGVFSLLGA-------SFQNRANMRMSAL 525
            |...|..|.|:|..|||..:|::.|||........|:|...|:..       :|:.     :.|:
Zfish   380 LTHFIYAAIEVPAKILVYFSLNKVGRRNTQTGTLVLTGFCILINIITPTEYWTFRT-----VIAV 439

  Fly   526 AGRFFSNICYNIGLQWAAEILPTVVRAQGVAFIHTMGFVAMLMSPPVVYLSK--KSLSSTLIVLG 588
            .|:..|...:...:.:..|:.|||:|..|:.|.:.|..:...:||.::.|..  |.|..  ::..
Zfish   440 LGKGLSEASFTTVILYTTELYPTVMRQNGLGFTNFMARMGASISPLIMLLEDIWKLLPE--VIFC 502

  Fly   589 ALGIFGGLLALFLPETLNHELPETLSD 615
            ::.||.|::||.||||.|..||||:.|
Zfish   503 SMAIFCGIIALLLPETNNASLPETVED 529

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10486	NP_647998.2	2A0119	104..612	CDD:273328	137/534 (26%)
CG10486	NP_647998.2	MFS	231..602	CDD:119392	97/391 (25%)
zmp:0000001102	XP_001340340.6	Sugar_tr	22..526	CDD:331684	137/533 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D284622at33208
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	3.010