Protein Alignment QC and QPCTL

DIOPT Version :10

• Sequence 1: NP_729109.1
• Gene: QC / 38663
• FlyBaseID: FBgn0052412
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: NP_060129.2
• Gene: QPCTL / 54814
• HGNCID: 25952
• Length: 382
• Species: Homo sapiens
• Alignment Length: 319
• Identity: 137/319 - (42%)
• Similarity: 177/319 - (55%)
• Gaps: 24/319 - (7%)

  Fly    18 LPPSHQQATAGNIGSQ--WRDDEVHFNRTLDSILVPRVVGSRGHQQVREYLVQSLNGL--GFQTE 78
            ||.:..:...|.:..|  |       :..|..:||.|..||.|:.|||::|..:|..|  |:..|
Human    76 LPEARLRRVVGQLDPQRLW-------STYLRPLLVVRTPGSPGNLQVRKFLEATLRSLTAGWHVE 133

  Fly    79 VDEFKQRVPVFGELTFANVVGTINPQAQNFLALACHYDSKYFPNDPG---FVGATDSAVPCAILL 140
            :|.|....|: |.:.|.|||.|::|:|...|.||||||||.||  ||   ||||||||||||:||
Human   134 LDPFTASTPL-GPVDFGNVVATLDPRAARHLTLACHYDSKLFP--PGSTPFVGATDSAVPCALLL 195

  Fly   141 NTAKTLGAYLQKEFRNRSDVGLMLIFFDGEEAFKEWTDADSVYGSKHLAAKLASKRSGSQAQLAP 205
            ..|:.|...|.:..:..:.|.|.|:|.|||||.|||...||:|||:|||..:.|.....    .|
Human   196 ELAQALDLELSRAKKQAAPVTLQLLFLDGEEALKEWGPKDSLYGSRHLAQLMESIPHSP----GP 256

  Fly   206 RNIDRIEVLVLLDLIGARNPKFSSFYENTDGLHSSLVQIEKSLRTAGQLEGNNNMFLSRVSG--- 267
            ..|..||:.:||||:||.||.|.|.:..|......|..|||.|.....|:.:....:....|
Human   257 TRIQAIELFMLLDLLGAPNPTFYSHFPRTVRWFHRLRSIEKRLHRLNLLQSHPQEVMYFQPGEPF 321

  Fly   268 GLVDDDHRPFLDENVPVLHLVATPFPDVWHTPRDNAANLHWPSIRNFNRVFRNFVYQYL 326
            |.|:|||.|||...||||||::||||.|||||.|...|||.|::.|..|:...|:.:||
Human   322 GSVEDDHIPFLRRGVPVLHLISTPFPAVWHTPADTEVNLHPPTVHNLCRILAVFLAEYL 380

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
QC	NP_729109.1	M28_QC_like	21..325	CDD:349876	133/313 (42%)
QPCTL	NP_060129.2	M28_QC_like	79..379	CDD:349876	133/313 (42%)