DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment QC and CG6168

DIOPT Version :9

Sequence 1:	NP_729109.1	Gene:	QC / 38663	FlyBaseID:	FBgn0052412	Length:	340	Species:	Drosophila melanogaster
Sequence 2:	NP_001287032.1	Gene:	CG6168 / 39273	FlyBaseID:	FBgn0036154	Length:	342	Species:	Drosophila melanogaster

Alignment Length:	317	Identity:	130/317 - (41%)
Similarity:	176/317 - (55%)	Gaps:	25/317 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 QATAGNIGSQWR-----DDEVHFNRTLDSILVPRVVGSRGHQQVREYLVQSLNGLGFQTEVDEFK 83
            :.|..|:| |.|     .|..:..:.:..|.:.|.|.:.||.:||.|:|..|..|.:..|:|.|.
  Fly    42 EPTELNLG-QMRMIAGLSDPENLRKNVQRIAIKRAVSTPGHSEVRNYIVDYLKKLNWNVELDIFT 105

  Fly    84 QRVPVFGELTFANVVGTINPQAQNFLALACHYDSKYFPNDPGFVGATDSAVPCAILLNTAKTLGA 148
            |:||:...:||.|:|...|||.|.:|...|||||||| .|..|:.|||||||||::||.|    .
  Fly   106 QKVPIMSNVTFHNIVARQNPQTQRYLMFGCHYDSKYF-KDFDFMAATDSAVPCALMLNMA----T 165

  Fly   149 YLQKEFRNRSDVGLMLIFFDGEEAFKEWTDADSVYGSKHLAAKLASKRSGSQAQLAPRNIDRIEV 213
            .|:.:| :||.|.|||:||||||||.||:..||.|||:|| |:|..|..         .:|:|::
  Fly   166 ILKHQF-HRSQVSLMLVFFDGEEAFGEWSQEDSPYGSRHL-AELWEKHG---------FLDKIDL 219

  Fly   214 LVLLDLIGARNPKFSSFYENTDGLHSSLVQIEKSLRTAGQLEGNNNMFLSRVSGGL-VDDDHRPF 277
            .||.|||||::..|.....:|.|....|||:|..|..||.:.....:|  :...|: |||||.||
  Fly   220 FVLPDLIGAKDVVFKKNILDTSGWFHRLVQLELKLFQAGIVRSERPLF--KFEPGIDVDDDHLPF 282

  Fly   278 LDENVPVLHLVATPFPDVWHTPRDNAANLHWPSIRNFNRVFRNFVYQYLKRHTSPVN 334
            ...||||:||::..:|.|||...|...|:.:.:......|.|.||.:||....|..|
  Fly   283 TRRNVPVIHLISNKYPAVWHQAEDVEMNVDYNTTEQVGLVLRMFVMEYLNSAPSISN 339

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
QC	NP_729109.1	M28_QC_like	36..325	CDD:193501	121/289 (42%)
CG6168	NP_001287032.1	M28_QC_like	49..330	CDD:193501	124/299 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45445047
Domainoid	1	1.000	168	1.000	Domainoid score	I792
eggNOG	1	0.900	-	-		E1_KOG3946
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	41	1.000	Inparanoid score	I487
Isobase	1	0.950	-	0.861353	Normalized mean entropy	S1680
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D117458at50557
OrthoFinder	1	1.000	-	-		FOG0001509
OrthoInspector	1	1.000	-	-		otm46906
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR12283
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1074
	11	10.850