DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment QC and Qpct

DIOPT Version :9

Sequence 1:	NP_729109.1	Gene:	QC / 38663	FlyBaseID:	FBgn0052412	Length:	340	Species:	Drosophila melanogaster
Sequence 2:	XP_006239694.1	Gene:	Qpct / 313837	RGDID:	1562284	Length:	362	Species:	Rattus norvegicus

Alignment Length:	326	Identity:	141/326 - (43%)
Similarity:	196/326 - (60%)	Gaps:	30/326 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 PSH-------QQATAGNIGSQWRDDEVHFNRTLDSILVPRVVGSRGHQQVREYLVQSLNGLGFQ- 76
            |:|       |.|.|.:|...|::|       |..:|:.|..||.|....|::::|.:..|..:
  Rat    46 PAHLNSSSLRQVAEATSISEMWQND-------LRPLLIERYPGSPGSYSARQHIMQRIQRLQAEW 103

  Fly    77 -TEVDEFKQRVPVFGELTFANVVGTINPQAQNFLALACHYDSKYFP--NDPGFVGATDSAVPCAI 138
             .|||.|..|.| :|..:|:|::.|:||:|:..|.|||||||||||  :...||||||||||||:
  Rat   104 VVEVDTFLSRTP-YGYRSFSNIISTLNPEAKRHLVLACHYDSKYFPQWDSRVFVGATDSAVPCAM 167

  Fly   139 LLNTAKTLGAYLQ--KEFR-NRSDVGLMLIFFDGEEAFKEWTDADSVYGSKHLAAKLASK--RSG 198
            :|..|:.|...|.  |:.. :|.|:.|.||||||||||..|:..||:|||:|||.|:||.  ..|
  Rat   168 MLELARALDKKLHSLKDVSGSRPDLSLRLIFFDGEEAFLHWSPQDSLYGSRHLAQKMASSPHPPG 232

  Fly   199 SQAQLAPRNIDRIEVLVLLDLIGARNPKFSSFYENTDGLHSSLVQIEKSLRTAGQLEGNN---NM 260
            |:   ....:|.:::|||||||||.||.|.:|:..|....:.|..||:.|...|.|:.::   ..
  Rat   233 SR---GTNQLDGMDLLVLLDLIGAANPTFPNFFPKTTRWFTRLQAIEQQLSELGLLKDHSLERKY 294

  Fly   261 FLSRVSGGLVDDDHRPFLDENVPVLHLVATPFPDVWHTPRDNAANLHWPSIRNFNRVFRNFVYQY 325
            |.:...|.::.|||.|||.:.||||||:|:|||:||||..||..|||..:|.|.|::.:.||.:|
  Rat   295 FQNFGYGNIIQDDHIPFLRKGVPVLHLIASPFPEVWHTMDDNEENLHSSTIDNLNKIIQVFVLEY 359

  Fly   326 L 326
            |
  Rat   360 L 360

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
QC	NP_729109.1	M28_QC_like	36..325	CDD:193501	132/300 (44%)
Qpct	XP_006239694.1	M28_QC_like	54..359	CDD:349876	137/315 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166338310
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3946
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55920
OrthoDB	1	1.010	-	-		D1257754at2759
OrthoFinder	1	1.000	-	-		FOG0001509
OrthoInspector	1	1.000	-	-		mtm9135
orthoMCL	1	0.900	-	-		OOG6_102560
Panther	1	1.100	-	-	O	PTHR12283
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1074
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	11.760