DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5592 and HXT9

DIOPT Version :9

Sequence 1:	NP_647996.1	Gene:	CG5592 / 38662	FlyBaseID:	FBgn0035645	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_012316.1	Gene:	HXT9 / 853236	SGDID:	S000003755	Length:	567	Species:	Saccharomyces cerevisiae

Alignment Length:	472	Identity:	106/472 - (22%)
Similarity:	171/472 - (36%)	Gaps:	122/472 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   135 KRDFGTY---------SVVVYFVGCIVGCLCFGFITDHSGRLPALFLANSCSMIGGCVSV--VCK 188
            |.|.|||         .|.::.:||.:|.:....:.|..||...|....:..::|..:.:  :.|
Yeast    98 KNDKGTYYLSKVRMGLIVSIFNIGCAIGGIVLSKVGDIYGRRIGLITVTAIYVVGILIQITSINK 162

  Fly   189 DFPCFAASRFVAGLSMNYCFVPIYILTLENVGIKYR-TLVG--NLALTFFFTLGACLLPWLAYVI 250
            .:..| ..|.::||.:....|...:|..|....:.| |||.  .|..|....||.|    ..|..
Yeast   163 WYQYF-IGRIISGLGVGGIAVLSPMLISEVAPKQIRGTLVQLYQLMCTMGIFLGYC----TNYGT 222

  Fly   251 SN------WRHYAMVVALPI-----VFMILTSLLAPESPSWLMSVGKVDRCIEVMKEAAKAN--- 301
            .|      ||     |.|.:     .||:...:..||||.:|:.|||.:   |..:..:|:|
Yeast   223 KNYHNATQWR-----VGLGLCFAWTTFMVSGMMFVPESPRYLIEVGKDE---EAKRSLSKSNKVS 279

  Fly   302 -------------------GKIISEEVWSEMRECYELKFANEQLG------KQYTSLDLFKTFPR 341
                               .|:.....|||:.......|....:|      :|.|..:.|..:..
Yeast   280 VDDPALLAEYDTIKAGIELEKLAGNASWSELLSTKTKVFQRVLMGVMIQSLQQLTGDNYFFYYGT 344

  Fly   342 LVVLTILIVTWMTVALAYDAHVRVVEILDTDIFITFSLSSLVEIPAGIVPMLLLDRIGRKPMM-- 404
            .:        :.:|.|             .|.|.|..:..:|...:..:.:..::|.||:..:
Yeast   345 TI--------FKSVGL-------------KDSFQTSIIIGVVNFFSSFIAVYTIERFGRRTCLLW 388

  Fly   405 -SAVMLLCAASSLFVGILK------GHWNASTAA------IAARFFATMAYNVGQQWA------- 449
             :|.||.|.|....||:.|      .|.:.::..      :...||   .::....||
Yeast   389 GAASMLCCFAVFASVGVTKLWPQGSSHQDITSQGAGNCMIVFTMFF---IFSFATTWAGGCYVIV 450

  Fly   450 SEILPTVLRGQGLAIINIMGQM-GALLS---PLVLSTHRYYRPLPMFIITLVSVIGALIILFLPE 510
            ||..|..::.:|:||......| |.|:|   |.:.....:|... :|:..||... ..:..|:||
Yeast   451 SETFPLRVKSRGMAIATAANWMWGFLISFFTPFITGAINFYYGY-VFLGCLVFAY-FYVFFFVPE 513

  Fly   511 TKGATMPQTLDEAEKRW 527
            |||.    ||:|....|
Yeast   514 TKGL----TLEEVNTMW 526

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5592	NP_647996.1	2A0119	17..519	CDD:273328	102/462 (22%)
CG5592	NP_647996.1	MFS	141..509	CDD:119392	93/446 (21%)
HXT9	NP_012316.1	Sugar_tr	64..526	CDD:395036	105/470 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000