Protein Alignment CG5592 and GIT1

DIOPT Version :10

• Sequence 1: NP_647996.1
• Gene: CG5592 / 38662
• FlyBaseID: FBgn0035645
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: NP_010022.1
• Gene: GIT1 / 850462
• SGDID: S000000695
• Length: 518
• Species: Saccharomyces cerevisiae
• Alignment Length: 421
• Identity: 87/421 - (20%)
• Similarity: 155/421 - (36%)
• Gaps: 106/421 - (25%)

  Fly   148 VGCIVGCLCFGFITDHSGRLPALFLANSCSMIGGCVSVVCKDFPCFAASRFVAGLSMNYCFVPIY 212
            ||.|.|....|...|:..|...:.:|.:..:||   |.:|      |||.......|.:....:.
Yeast    95 VGIIFGQFFMGIAADYYSRKSCILVATAILVIG---SALC------AASHGTTVPGMFWMLTVMR 150

  Fly   213 ILTLENVGIKY--RTLVGNLALTFFFTL--GACLLPWLAYVISNWRHYAMVVALPIVFMILTSLL 273
            .|....||.:|  .||..|.:...:.|.  |..|:              ||..||:.|.
Yeast   151 GLVGIGVGAEYPTSTLSANESANEYTTTKRGGILV--------------MVTNLPLAFG------ 195

  Fly   274 APESPSWLMSVGKV---DRCIEVMKEAAKANG------------KIISEEVWSEMR------ECY 317
            .|.:....:.|.|:   .:.:|.:.....|.|            |..:.||:.:.|      ...
Yeast   196 GPFATIIFLIVYKICSGTKHLEAIWRTVFAIGCFWPLSVFYFRWKTATTEVYEKGRIKRNIPYFL 260

  Fly   318 ELKFANEQL----GKQYTSLDLFKTFPRLVVLTILIVTWMTVALAYDAHVRVVEILDTDIFITFS 378
            .|||..::|    |..:  :..|.|||..:..:.:|     .::..|.: .:|::.:.::.:  .
Yeast   261 ALKFYWKRLLGTCGTWF--MYDFVTFPNGIFSSTII-----SSVIKDQN-DLVKVAEWNLLL--G 315

  Fly   379 LSSLVEIPAGIVPMLLLDRIGRKPMMSAVMLLCAASSLFVGILKGHWNASTAAIAARF-----FA 438
            :.:::.:|.|   ..|.||||||    ..::...:..:..|::.|........|...|     |.
Yeast   316 VLAVLGVPIG---AYLSDRIGRK----YTLMFGFSGYIIFGLIIGCAYDQLKKITPLFIIFYAFM 373

  Fly   439 TMAYNVGQ-----QWASEILPTVLRGQGLAIINIMGQMGALLSPLVLSTHRYYRPLP-------M 491
            .|..|.|.     ..:||...|.:||....:..:.|::|:::..      ..::|:.       .
Yeast   374 NMLGNAGPGDMLGVISSEASATAVRGVFYGLSAVTGKIGSVVGV------ECFQPIRDNLGARWT 432

  Fly   492 FIITLV-SVIGALIILFLPETKGATMPQTLD 521
            |||..: .:||.:|..|.       :|.:|:
Yeast   433 FIIAAICGLIGIIITYFF-------VPHSLE 456

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5592	NP_647996.1	MFS_SLC22	113..509	CDD:340875	85/407 (21%)
GIT1	NP_010022.1	MFS_PhT	48..454	CDD:340922	86/417 (21%)