DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5592 and OCT1

DIOPT Version :9

Sequence 1:	NP_647996.1	Gene:	CG5592 / 38662	FlyBaseID:	FBgn0035645	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_565059.2	Gene:	OCT1 / 843656	AraportID:	AT1G73220	Length:	539	Species:	Arabidopsis thaliana

Alignment Length:	552	Identity:	119/552 - (21%)
Similarity:	215/552 - (38%)	Gaps:	156/552 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    89 NVPYDSNATNDANQTRSPIPCNN------------------------------GWIYDRKEV--- 120
            |:..||:||.....||.....||                              .||:|.:..
plant    17 NISNDSSATEKGEATRQQQLPNNRYALTVDEVIEQHIGALGFAQILHALLVSIAWIFDAQTTLIS 81

  Fly   121 ------------------------------------PYESIATEYNWVCDKRDFGTYSVVVYFVG 149
                                                ..:::.:|:|.:|..:........::|:|
plant    82 IFSDAQPAARLLATGAIVEGASLCGLASGEWEWIGPKSDTVVSEWNLICQHKFLVAVPSTLFFIG 146

  Fly   150 CIVGCLCFGFITDH-SGRLPALFLANSCSMIGGCVSVVCKDFP--------CFAASRFVAGL--- 202
            .:.|...:|::.|. .||...|.|:        ||......|.        .:|..||..|.
plant   147 SLFGSGVYGYLADSWFGRKKTLLLS--------CVLTFVTAFAISFSPNVWVYAFLRFANGFFRS 203

  Fly   203 SMNYCFVPIYILTLENVGIKYRTLVGNLALTFFFTLGACLLPWLAYV-ISNWRH-YAMVVALPIV 265
            .:..|.:   :|..|.||.|:|..||.... ||||||...||.:||: ..:||: |.::..||:.
plant   204 GIGSCCI---VLATEIVGKKWRGQVGQYGF-FFFTLGFLSLPLMAYLERKSWRNLYRIISFLPLG 264

  Fly   266 FMILTSLLAPESPSWLMSVGKVDRCIEVMKEAAKANGKII-------------------SEEVWS 311
            :.:.....|.|||.||:..|:....:.|:|:.|:.|||.:                   ||:.|
plant   265 YAVCLLPFAYESPRWLLVKGRNKEAMVVLKKLARLNGKQLPADLSLVDPIPERDDQTSSSEKFW- 328

  Fly   312 EMRECYELKFANEQLGKQYTSLDLFKTFPRLVVLTILIVTWMTVALAYDAHVRVVEILDTDIFIT 376
                  :.|:|.::                  ::.:::..:.:..:.|...:. .|.|:.::::|
plant   329 ------KTKWAVKR------------------IIMVMMAGFGSGFVYYGIQLN-AENLNFNLYLT 368

  Fly   377 FSLSSLVEIPAGIVPMLLLDRIGRKPMMS-------AVMLLCAASSLF-----VGILKGHWNAST 429
            .::::|:|.||..:...||..:.|:|:.|       ...||||..|:.     :.:.|  | ...
plant   369 VAVNALMEFPAVFIGSFLLGVMNRRPLFSNSSYLAGFACLLCAVLSIHRVIRAISVAK--W-LQL 430

  Fly   430 AAIAARFFA-TMAYNVGQQWASEILPTVLRGQGLAIINIMGQMGALLSPLVLSTHRYYRPLPMFI 493
            |..|..|.| :.||:|...:..|:.||.:|...::::.....:||..:||:::..|....:...:
plant   431 AVEAVGFMASSTAYDVLYVYCVELFPTNVRNTAVSLLRQAFMLGASAAPLLVALGRESAMMSFIV 495

  Fly   494 ITLVSVIGALIILFLPETKGATMPQTLDEAEK 525
            ..:.||:..::.|:|.||:.|.:.:||.:..|
plant   496 FGVASVLSGIVSLWLRETRNAPLYETLAQQGK 527

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5592	NP_647996.1	2A0119	17..519	CDD:273328	116/544 (21%)
CG5592	NP_647996.1	MFS	141..509	CDD:119392	97/413 (23%)
OCT1	NP_565059.2	MFS_OCT_plant	102..511	CDD:340936	100/449 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.100