DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5592 and oct2

DIOPT Version :9

Sequence 1:	NP_647996.1	Gene:	CG5592 / 38662	FlyBaseID:	FBgn0035645	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_001107932.1	Gene:	oct2 / 797890	ZFINID:	ZDB-GENE-080204-92	Length:	554	Species:	Danio rerio

Alignment Length:	558	Identity:	164/558 - (29%)
Similarity:	275/558 - (49%)	Gaps:	55/558 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 YENFLLFIGDFGPFQKRLLFWMMPAAFLFAFTYFGQIFMILLPKNHWCRVRELE---GLPESEQK 70
            ::..|...||||.:|||:.........|.||...|.:|:...| :|||:...|:   |..|.:.:
Zfish     4 FDELLQHAGDFGFYQKRISVLGSLPILLLAFVLIGVVFLGYTP-DHWCKTASLQEKCGFSEEQVR 67

  Fly    71 NRGIPKK-QDGSFENCFMYNVPYDSNATNDA---------NQTRSPIPCNNGWIYDRKEVPYESI 125
            :..:|:. ..|:|..|    |.:|....|.:         |.:.....||.||.::....   :|
Zfish    68 DLTVPRTGARGAFSKC----VKFDDALRNGSALSCNISIFNNSTHLSACNEGWTFNENRT---TI 125

  Fly   126 ATEYNWVCDKRDFGTYSVVVYFVGCIVGCLCFGFITDHSGRLPALFLANSCSMIGGCVSVVCKDF 190
            .||::.||:.......:.|....|..:|.|..|::.|..|| .:.|:|   |:.|..||..|..|
Zfish   126 VTEFSLVCEDSWLADLNQVSLAGGFFIGALVTGYLADRFGR-KSCFIA---SIFGLGVSGTCIIF 186

  Fly   191 ----PCFAASRFVAGLSMNYCFVPIYILTLENVGIKYRTLVGNLALTFFFTLGACLLPWLAYVIS 251
                |.....|.:.|......:...|:|.:|..|...|..|..::.| |::||..|||.|||.|.
Zfish   187 SPYYPLLLFFRCLQGFFAKGAWTATYVLIIEFFGSNNRKFVSVMSRT-FYSLGLVLLPALAYYIP 250

  Fly   252 NWRHYAMVVALPIVFMILTSLLAPESPSWLMSVGKVDRCIEVMKEAAKANGKIISEEVWSEMREC 316
            :||:..:.:.||....::...:.||||.||:|..|....:.::|..||.|.:.:.|: :.||...
Zfish   251 SWRNLQLAMTLPTFIFLIYHWVIPESPRWLLSQRKTKEALSIVKSIAKCNKRSLPED-FHEMDLL 314

  Fly   317 YELKFANEQLGKQYTSLDLFKTFPRLVVLT-ILIVTWMTVALAYDAHVRVVEILDTDIFITFSLS 380
            .|.:  .|.:...|.  ||||| |::...| |||..|.|.|:.:...|..:.|...::|:.|.:|
Zfish   315 IEKQ--EEIMRPSYK--DLFKT-PKMRKHTFILIYAWFTGAVVFQGLVLRLGITGDNVFLDFLIS 374

  Fly   381 SLVEIPAGIVPMLLLDRIGRKPMMSAVMLLCAASSLFVGILKGH--WNASTAAIAARFFATMAYN 443
            ::||:|.|::...|:|||||:|:|:.|..:..|:.|.|..:..:  |...|.||..|    :|..
Zfish   375 AVVELPTGLIFYFLVDRIGRRPLMATVNFIGGAACLAVPFISPNISWLRRTIAIVGR----LAVA 435

  Fly   444 VGQQWA----SEILPTVLRGQGLAIINIMGQMGALLSPLVLSTHR---YYRPLPMFIITLVSVIG 501
            :|.:..    :|:.||.||..|:::.:....:||:::|.:|  :|   .::.||:.:..::||:.
Zfish   436 IGNETVNFANTELYPTPLRNLGVSVCSSASDIGAVVAPFIL--YRLASIWQELPLLVYGVMSVLY 498

  Fly   502 ALIILFLPETKGATMPQTLDEAEKRWTLRCRDRKINED 539
            :.:::.|||.||..:|:|:|:.|   .||.|.::..:|
Zfish   499 SGLVMLLPEMKGVDLPETVDDVE---NLRSRHKRKEKD 533

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5592	NP_647996.1	2A0119	17..519	CDD:273328	156/528 (30%)
CG5592	NP_647996.1	MFS	141..509	CDD:119392	114/381 (30%)
oct2	NP_001107932.1	2A0119	12..516	CDD:273328	156/528 (30%)
oct2	NP_001107932.1	MFS	123..506	CDD:119392	119/402 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170588942
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9N9
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	7.850