Protein Alignment CG5592 and Slc22a23

DIOPT Version :9

• Sequence 1: NP_647996.1
• Gene: CG5592 / 38662
• FlyBaseID: FBgn0035645
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: NP_001028339.1
• Gene: Slc22a23 / 73102
• MGIID: 1920352
• Length: 689
• Species: Mus musculus
• Alignment Length: 602
• Identity: 134/602 - (22%)
• Similarity: 248/602 - (41%)
• Gaps: 130/602 - (21%)

  Fly     9 YENFLL-FIGDF-GPFQKRL--LFWMMPAAFLFAFTYFGQIFMILLPKNHWCR----VRELEGLP 65
            |:..:| |:|.. |.:||.|  |.| :||.|: .|:.|...|::..| :.|||    ..||.|..
Mouse    80 YDGSVLPFLGGLGGGYQKTLVVLTW-IPALFI-GFSQFSDSFLLDQP-DFWCRGAGKGTELAGAT 141

  Fly    66 ES----EQKNRGIPKKQDGSFENCFMYNVPYD-------SNATNDANQTRSPIPCNNG------- 112
            .:    :..|...|..            .|:.       ||.:|.::....|.|...|
Mouse   142 VTGRWGDMGNWTSPSA------------TPFSTASWGTTSNRSNSSDTPPLPSPPGKGNNDSNCD 194

  Fly   113 ---WIYDRKEVPYESIATEYNWVCDKRDFGTYSVVV----YFVGCIVGCLCFGFITDHSGRLPAL 170
               |.|..:....:::.::::.|||    .|:.|.:    ..||.|.|.|..|.|.|..||.|.|
Mouse   195 CHAWDYGIRTGLIQNVVSKWDLVCD----NTWKVHIAKFSLLVGLIFGYLITGCIADWVGRRPVL 255

  Fly   171 FLANSCSMIGGCVSVVCKDFPCFAASRFVAGLSMNYCFVPIYILTLENVGIKYRTLVGNLALTFF 235
            ..:....:|.|....:..:...|:..||..|..:....:.:|.|.:|......|.:: .:..:|.
Mouse   256 LFSTIFILIFGLTVALSVNVTMFSTLRFFEGFCLAGIILTLYALRIELCPPGKRFII-TMVASFV 319

  Fly   236 FTLGACLLPWLAYVISNWRHYAMVVALPIVFMILTSLLAPESPSWLMSVGKVDRCIEVMKEAAKA 300
            ...|..|:|.||.:..:|:....::..|.:.|:|...:.|||..|||:..:.        |:||
Mouse   320 AMAGQFLMPGLAALCRDWQVLQALIICPFLLMLLYWSIFPESLRWLMATQQF--------ESAK- 375

  Fly   301 NGKIISEEVWSEMRECY----ELKFANEQLGKQYT-------------SLDLFKTFPRLVVLTIL 348
              |:|   ::...:.|.    ::|....:|.|:.:             :.:|:|   .:|||.:.
Mouse   376 --KLI---LYLTQKNCVSPESDIKGVMPELEKELSRRPKKVCIVKVVGTRNLWK---NIVVLCVN 432

  Fly   349 IVTWMTV-------ALAYDAHVRVVEILDTDIFITFSLSSLVEIPAGIVPMLLLDRIGRKPMMSA 406
            .:|...:       .:.::..|.::|....|.:...|::    :.:.:...|::..:||:..:..
Mouse   433 SLTGYGIHHCFARSMMGHEVKVPLLENFYADYYTMASIA----LASCLAMCLVVKFLGRRGGLLL 493

  Fly   407 VMLLCAASSLF-VGILK--GHWN-------------ASTAAIAARFFATMAYNVGQQWAS----- 450
            .|:|.|.:||. :|:|.  |.::             ..:.::..:|  ::|:::...:||
Mouse   494 FMILTALASLLQLGLLNLIGKYSQHPDSELQLKLAVGMSDSVKDKF--SIAFSIVGMFASHAVGS 556

  Fly   451 -------EILPTVLRGQGLAIINIMGQMGALLSPLV-LSTHRYYRPLPMFIITLVSVIGALIILF 507
                   ||.|||:|..||.::......|.|.:|:: |...:.|. |...|....::|..:.||.
Mouse   557 LSVFFCAEITPTVIRCGGLGLVLASAGFGMLTAPIIELHNQKGYF-LHHIIFACCTLICIICILL 620

  Fly   508 LPETKGATMPQTLDEAE 524
            |||::...:|:.:...|
Mouse   621 LPESRNQNLPENIANGE 637

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5592	NP_647996.1	2A0119	17..519	CDD:273328	130/586 (22%)
		MFS	141..509	CDD:119392	91/424 (21%)
Slc22a23	NP_001028339.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..55
		2A0119	98..631	CDD:273328	125/576 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	162..188		5/25 (20%)
		MFS	230..>359	CDD:119392	32/129 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167843361
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.030