Protein Alignment CG5592 and Slc22a16

DIOPT Version :10

• Sequence 1: NP_647996.1
• Gene: CG5592 / 38662
• FlyBaseID: FBgn0035645
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: NP_081848.1
• Gene: Slc22a16 / 70840
• MGIID: 1918090
• Length: 649
• Species: Mus musculus
• Alignment Length: 565
• Identity: 127/565 - (22%)
• Similarity: 239/565 - (42%)
• Gaps: 81/565 - (14%)

  Fly    13 LLF--IGDFGPFQKRLLFWMMPAAFLFAFTYFGQIFMILLPKNHWC-----------------RV 58
            |:|  ||.||.||..|.......:......|...:|:.::|: |.|                 |:
Mouse     8 LIFDHIGHFGRFQIVLYLICAYQSLSCGIHYLSSVFLSIIPE-HACKPPGMVRKAVFHNVSAWRL 71

  Fly    59 RELEGLPESEQKNRGIPKKQDGSF-----------ENCFMYNVPYDSNATNDANQTRSPIPCNNG 112
            .::..|...|.|:..:.:.|||..           ||.......| |...:|:       ||.:|
Mouse    72 EDILALRSPEHKDHIMVELQDGEIWELTRCSRTWRENTSHLGYEY-SGYKHDS-------PCFDG 128

  Fly   113 WIYDRKEVPYESIATEYNWVCDKRDFGTYSVVVYFVGCIVGCLCFGFITDHSGRLPALFLANSCS 177
            ::||:.:. ..|....:|.|||::.:......:...|.::|.:.|.:::|..||..||:    |:
Mouse   129 YVYDQSKW-RNSAVRNFNLVCDQKWYARMIQPLIIFGVMLGSITFSYLSDRFGRRMALW----CT 188

  Fly   178 MIG----GCVSVVCKDFPCFAASRFVAGLSMNYCFVPIYILTLENVGIKYRTLVGNLALTFFFTL 238
            .||    |..|:...|:..|..:||...::.:..||.:::..:|.:|.|.||. .::.|..||.:
Mouse   189 SIGVFFFGIASLFIFDYLSFMITRFFLVMASSGYFVVVFVYVMEIIGKKARTW-ASIHLNTFFAI 252

  Fly   239 GACLLPWLAYVISNWRHYAMVVALPIVFMILTSLLAPESPSWLMSVGKVDRCIEVMKEAAKANGK 303
            ||.|:...:|::..|..|.:::.:.....||...:.||:|.||:|.|:       .||   |.|.
Mouse   253 GAMLVALASYLLKTWWLYQIILCIVTTPFILCCWMLPETPFWLLSEGR-------YKE---AQGT 307

  Fly   304 IISEEVWSEMRECYELKFANEQLGKQYTS----------LDLFKTFPRLVVLTILIVTWMTVALA 358
            :.:..||::...|..::..:..:.:.:..          .|||.......:..|:.:.|.|..|.
Mouse   308 VDTMAVWNKSSSCDLVELLSLDVTRSHNKSPHSIRKHRLADLFHNLDVAKMTLIVWLDWFTANLG 372

  Fly   359 YDAHVRVVEILDTDIFITFSLSSLVEIPAGIVPMLLLDRIGRKPMMSAVMLLCAASSLFVGILKG 423
            |....:.|.....:..:...|...:||||.|...:.|.|:||:..|...:|:.:.:.:...::..
Mouse   373 YYMFGKEVIRRKENEPLYLLLVGAMEIPAYICLCIWLKRVGRRKTMLLFLLVSSLTCMLHVVMPS 437

  Fly   424 HWNASTAAIAARFFATMAYNVGQQ-------WASEILPTVLRGQGLAIINIMGQMGALLSPLVLS 481
            .:..     |.|..|.:..:|...       :.:|:.||.:|...:...|::..:.::..|....
Mouse   438 DYKT-----AKRMVALLVKSVISSVFAFIYLYTAELYPTTVRCLAVGSSNMVSHVSSIFIPFTSH 497

  Fly   482 THRYYRPLPMFIITLVSVIGALIILFLPETKGATMPQTLDEAEKR 526
            ..:.:..||..:..:::::..|:.|.||||:...|..|.:..|::
Mouse   498 FSKVWIFLPQILFGILAILSGLLSLKLPETQDTPMKSTWETTEQQ 542

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5592	NP_647996.1	MFS_SLC22	113..509	CDD:340875	91/416 (22%)
Slc22a16	NP_081848.1	MFS_SLC22A16_CT2	118..525	CDD:340933	95/434 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	530..560		3/13 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	579..649