Protein Alignment CG5592 and Slc22a23

DIOPT Version :9

• Sequence 1: NP_647996.1
• Gene: CG5592 / 38662
• FlyBaseID: FBgn0035645
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: NP_072146.1
• Gene: Slc22a23 / 64559
• RGDID: 620302
• Length: 689
• Species: Rattus norvegicus
• Alignment Length: 602
• Identity: 137/602 - (22%)
• Similarity: 249/602 - (41%)
• Gaps: 130/602 - (21%)

  Fly     9 YENFLL-FIGDF-GPFQKRL--LFWMMPAAFLFAFTYFGQIFMILLPKNHWC----RVRELEGLP 65
            |:..:| |:|.. |.:||.|  |.| :||.|: .|:.|...|::..| |.||    :..||.|..
  Rat    80 YDGSVLPFLGGLGGGYQKTLVVLTW-IPALFI-GFSQFSDSFLLDQP-NFWCHGAGKGTELAGAT 141

  Fly    66 ES----EQKNRGIPKKQDGSFENCFMYNVPYD-------SNATNDANQTRSPIPCNNG------- 112
            .:    :..|...|..            .|:.       ||.:|.::....|.|...|
  Rat   142 VTGRWGDMGNWTSPSA------------TPFSTASWGTTSNRSNSSDTPPLPSPPGKGNNDSNCE 194

  Fly   113 ---WIYDRKEVPYESIATEYNWVCD---KRDFGTYSVVVYFVGCIVGCLCFGFITDHSGRLPALF 171
               |.|..:....:::.::::.|||   |.....:|::   ||.|.|.|..|.|.|..||.|.|.
  Rat   195 CHAWDYGIRTGLVQNVVSKWDLVCDNAWKVHVAKFSLL---VGLIFGYLITGCIADWVGRRPVLL 256

  Fly   172 LANSCSMIGGCVSVVCKDFPCFAASRFVAGLSMNYCFVPIYILTLENVGIKYRTLVGNLALTFFF 236
            .:....:|.|....:..:...|:..||..|..:....:.:|.|.:|......|.:: .:..:|..
  Rat   257 FSVIFILIFGLTVALSVNVTMFSTLRFFEGFCLAGIILTLYALRIELCPPGKRFII-TMVASFVA 320

  Fly   237 TLGACLLPWLAYVISNWRHYAMVVALPIVFMILTSLLAPESPSWLMSVGKVDRCIEVMKEAAKAN 301
            ..|..|:|.||.:..:|:....::..|.:.|:|...:.|||..|||:..:.        |:||
  Rat   321 MAGQFLMPGLAALCRDWQVLQALIICPFLLMLLYWSIFPESLRWLMATQQF--------ESAK-- 375

  Fly   302 GKIISEEVWSEMRECY----ELKFANEQLGKQYT-------------SLDLFKTFPRLVVLTILI 349
             |:|   ::...:.|.    ::|....:|.|:.:             :.:|:|   .:|||.:..
  Rat   376 -KLI---LYLTQKNCVSPESDIKGVMPELEKELSRRPKKVCIVKVVGTRNLWK---NIVVLCVNS 433

  Fly   350 VTWMTV-------ALAYDAHVRVVEILDTDIFITFSLSSLVEIPAGIVPMLLLDR-IGRKPMMSA 406
            :|...:       .:.::..|.::|....|.:...|::.     |..:.|.|:.| :||:..:..
  Rat   434 LTGYGIHHCFARSMMGHEVKVPLLENFYADYYTMASIAL-----ASCLAMCLVVRFLGRRGGLLL 493

  Fly   407 VMLLCAASSLF-VGILK--GHWN-------------ASTAAIAARFFATMAYNVGQQWAS----- 450
            .|:|.|.:||. :|:|.  |.::             ..:.::..:|  ::|:::...:||
  Rat   494 FMILTALASLLQLGLLNLIGKYSQHPDSELQLKLAVGMSDSVKDKF--SIAFSIVGMFASHAVGS 556

  Fly   451 -------EILPTVLRGQGLAIINIMGQMGALLSPLV-LSTHRYYRPLPMFIITLVSVIGALIILF 507
                   ||.|||:|..||.::......|.|.:|:: |...:.|. |...|....::|..:.||.
  Rat   557 LSVFFCAEITPTVIRCGGLGLVLASAGFGMLTAPIIELHNQKGYF-LHHIIFACCTLICIICILL 620

  Fly   508 LPETKGATMPQTLDEAE 524
            |||::...:|:.:...|
  Rat   621 LPESRDQNLPENIANGE 637

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5592	NP_647996.1	2A0119	17..519	CDD:273328	133/586 (23%)
		MFS	141..509	CDD:119392	94/421 (22%)
Slc22a23	NP_072146.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..55
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	162..188		5/25 (20%)
		MFS_SLC22A23	187..608	CDD:341002	98/449 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166346875
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.030