Protein Alignment CG5592 and Sv2b

DIOPT Version :10

• Sequence 1: NP_647996.1
• Gene: CG5592 / 38662
• FlyBaseID: FBgn0035645
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: NP_705807.2
• Gene: Sv2b / 64176
• MGIID: 1927338
• Length: 683
• Species: Mus musculus
• Alignment Length: 659
• Identity: 126/659 - (19%)
• Similarity: 211/659 - (32%)
• Gaps: 235/659 - (35%)

  Fly    60 ELEGLPESE----QKNRGIPKKQDG--------------SFENCFMYNVPYDSNATNDANQTRSP 106
            |.:|:|..:    ::.:..|.:.||              ..|....|....|.
Mouse    49 EYQGIPHPDDVKSKQTKMAPSRADGLGGQADLMAERMEDEEELAHQYETIIDE------------ 101

  Fly   107 IPCNNG---W----------IYDRKEVPYESIA---TEYNWVCDKRDFGTYSVVVYFVGCIVGCL 155
              |.:|   |          :.|..|:...|.|   .|.:........|...::|| :|.:.|..
Mouse   102 --CGHGRFQWTLFFVLGLALMADGVEIFVVSFALPSAEKDMCLSSSKKGMLGLIVY-LGMMAGAF 163

  Fly   156 CFGFITDHSGRLPALFLANSCSMIGGCVSVVCKDFPCFAASRFVAGLSMNYCFVPIY-----ILT 215
            ..|.:.|..||...|.::.:.:.....:|...:.:..|...|.::|:.:......::     .|:
Mouse   164 ILGGLADKLGRKKVLSMSLAINASFASLSSFVQGYGAFLFCRLISGIGIGGSLPIVFAYFSEFLS 228

  Fly   216 LENVGIKYRTLVGNLALTFFFTLG--ACLLPW-------------LAYVISNWRHYAMVVALPIV 265
            .|..| ::.:.:|    .|:.|.|  |..:.|             ..|...:||.:.:|.|||..
Mouse   229 REKRG-EHLSWLG----IFWMTGGIYASAMAWSIIPHYGWGFSMGTNYHFHSWRVFVIVCALPAT 288

  Fly   266 FMILTSLLAPESPSWLMSVGKVDRCIEVMKEAAKAN--GKIISEEVWS--------EMRECYELK 320
            ..::.....||||.:|:.:||.|....::|:....|  .|...|:|::        :|.|..|::
Mouse   289 VSMVALKFMPESPRFLLEMGKHDEAWMILKQVHDTNMRAKGTPEKVFTVSHIKTPKQMDEFIEIQ 353

  Fly   321 FANEQLGKQYTS-----LDLFKTF----------PRLVVLTILIVTWMTVALAY----------- 359
               ...|..|..     :.:||..          |..:...||.|.|.|:||:|
Mouse   354 ---SSTGTWYQRWLVRFMTIFKQVWDNALYCVMGPYRMNTLILAVVWFTMALSYYGLTVWFPDMI 415

  Fly   360 ---------------------------------DAHVRVV------------------------- 366
                                             ..|.::|
Mouse   416 RYFQDEEYKSKMKVFFGEHVHGATINFTMENQIHQHGKLVNDKFIKMYFKHVLFEDTFFDKCYFE 480

  Fly   367 EILDTD---------------------------------------------------IFITFSLS 380
            ::..||                                                   |::...|.
Mouse   481 DVTSTDTYFKNCTIESTTFYNTDLYKHKFINCRFINSTFLEQKEGCHMDFEEDNDFLIYLVSFLG 545

  Fly   381 SLVEIPAGIVPMLLLDRIGRKPMMSAVMLLCAASS--LFVGILKGHWNASTAAIA--ARFFAT-- 439
            ||..:|..|:..||:|||||..|:...||:.|...  ||.|      |:.:|.|.  ..|..|
Mouse   546 SLSVLPGNIISALLMDRIGRLKMIGGSMLISAVCCFFLFFG------NSESAMIGWQCLFCGTSI 604

  Fly   440 MAYNVGQQWASEILPTVLRGQGLAIINIMGQMGALLSPLVLSTH-RYYRPLPMFIITLVSVIGAL 503
            .|:|.......|:.||..|.....|:|.:.:.||:|...:.::. ...:.:|:.:.....|.|.|
Mouse   605 AAWNALDVITVELYPTNQRATAFGILNGLCKFGAILGNTIFASFVGITKVVPILLAAASLVGGGL 669

  Fly   504 IILFLPETK 512
            |.|.||||:
Mouse   670 IALRLPETR 678

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5592	NP_647996.1	MFS_SLC22	113..509	CDD:340875	111/580 (19%)
Sv2b	NP_705807.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..73		4/23 (17%)
		synapt_SV2	8..683	CDD:130366	126/659 (19%)