Protein Alignment CG5592 and Slc22a4

DIOPT Version :10

• Sequence 1: NP_647996.1
• Gene: CG5592 / 38662
• FlyBaseID: FBgn0035645
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: NP_071606.1
• Gene: Slc22a4 / 64037
• RGDID: 621149
• Length: 553
• Species: Rattus norvegicus
• Alignment Length: 552
• Identity: 152/552 - (27%)
• Similarity: 269/552 - (48%)
• Gaps: 33/552 - (5%)

  Fly     9 YENFLLFIGDFGPFQKRLLFWMMPAAFL-FAFTYFGQIFMILLPKNHWCRVRELEGLPESEQKNR 72
            |:..:.|:||:|||| ||:|:::.|:.: ..|.....:|:...|: |.|.|.....| .|..:|.
  Rat     4 YDEVIAFLGDWGPFQ-RLIFFLLSASIIPNGFNGMSVVFLAGTPE-HRCLVPHTVNL-SSAWRNH 65

  Fly    73 GIP-KKQDGSF--ENCFMYNVPYDSNATN---------DANQTRSPIPCNNGWIYDRKEVPYESI 125
            .|| :.:||..  ::|..|.:...:|.:.         |..|.... .|.:||.|. |:|...:|
  Rat    66 SIPLETKDGRQVPQSCRRYRLATIANFSALGLEPGLDVDLEQLEQE-SCLDGWEYS-KDVFLSTI 128

  Fly   126 ATEYNWVCDKRDFGT-YSVVVYFVGCIVGCLCFGFITDHSGRLPALFLANSCSMIGGCVSVVCKD 189
            .||:|.||:. |:.| .:..::|||.:.|....|.::|..||...||...:.......|.:...:
  Rat   129 VTEWNLVCED-DWKTPLTTSLFFVGVLCGSFVSGQLSDRFGRKKVLFATMAVQTGFSFVQIFSTN 192

  Fly   190 FPCFAASRFVAGLSMNYCFVPIYILTLENVGIKYRTLVGNLALTFFFTLGACLLPWLAYVISNWR 254
            :..|.....:.|:.....:|..:||..|.:....|.|...|.:..||.:|..:||..||.|.:||
  Rat   193 WEMFTVLFAIVGMGQISNYVVAFILGTEILSKSVRILFSTLGVCTFFAIGYMVLPLFAYFIRDWR 257

  Fly   255 HYAMVVALPIVFMILTSLLAPESPSWLMSVGKVDRCIEVMKEAAKANGKIISEEVWSEMRECYEL 319
            ...:.:.||.:|.:......||||.||:|..:.:...:::::|||.|| |::..|..:..|..||
  Rat   258 MLLLALTLPGLFCVPLWWFIPESPRWLISQRRFEEAEQIIQKAAKMNG-IMAPAVIFDPLELQEL 321

  Fly   320 KFANEQLGKQYTSLDLFKTFPRLVVLTILIVTWMTVALAYDAHVRVVEILDTDIFITFSLSSLVE 384
            ....:|   :...||||||.....:..:.::.||..::.|.|....|..|..|:::...||.|:|
  Rat   322 NSLKQQ---KVFILDLFKTRNIATITVMSVMLWMLTSVGYFALSLNVPNLHGDVYLNCFLSGLIE 383

  Fly   385 IPAGIVPMLLLDRIGRKPMMSAVMLLCAASSLFVGILKGHWNASTAAIA--ARFFATMAYNVGQQ 447
            :||.....|||..:.|:.:::.|:.......|.|.::...:|..:..:.  .:|..|.|:::...
  Rat   384 VPAYFTAWLLLRTLPRRYIIAGVLFWGGGVLLLVQVVPEDYNFVSIGLVMLGKFGVTSAFSMLYV 448

  Fly   448 WASEILPTVLRGQGLAIINIMGQMGALLSPLVLSTHRYYRPLPMFIITLVSVIGALIILFLPETK 512
            :.:|:.||::|...:.|.::..::|::::|..:....|.|.||..::..::|:..:|.||.||:.
  Rat   449 FTAELYPTLVRNMAVGITSMASRVGSIIAPYFVYLGAYNRLLPYILMGSLTVLIGIITLFFPESF 513

  Fly   513 GATMPQTLDEAEKRWTLRC-------RDRKIN 537
            |.|:|:.|::.:|....||       .||:.|
  Rat   514 GVTLPENLEQMQKVRGFRCGKKSTVSMDREEN 545

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5592	NP_647996.1	MFS_SLC22	113..509	CDD:340875	108/398 (27%)
Slc22a4	NP_071606.1	2A0119	12..519	CDD:273328	142/516 (28%)