Protein Alignment CG5592 and sv2ca

DIOPT Version :9

• Sequence 1: NP_647996.1
• Gene: CG5592 / 38662
• FlyBaseID: FBgn0035645
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: NP_001121811.1
• Gene: sv2ca / 562345
• ZFINID: ZDB-GENE-060526-233
• Length: 745
• Species: Danio rerio
• Alignment Length: 695
• Identity: 125/695 - (17%)
• Similarity: 224/695 - (32%)
• Gaps: 273/695 - (39%)

  Fly    62 EGLPESEQKNRGIPKKQDGSFENCFMYNVPYDSNATNDANQTRSPIPCNNGWIYDRKEV------ 120
            ||..::.:.:....:..:|.::     .:|.|:.|.:  .|.....|.::| :.||:|:
Zfish    75 EGSSDATEGHDDEDEIYEGEYQ-----GIPSDAKARD--GQVALGQPLSDG-LKDRRELENERQA 131

  Fly   121 PYESIATEYNWVCDKRDFGTYSVVVYF-------------------------------------- 147
            ..|.:|.:|..:..:...|.:...::|
Zfish   132 DEEELAQQYELIIQECGHGRFQWQLFFTLGLALMSDGVEVFVVGFVLPSAETDMCVPDSSSGWLG 196

  Fly   148 ----VGCIVGCLCFGFITDHSGRLPALFLANS--------------------CSM-----IGGCV 183
                :|.:||...:|.:.|..||...|.:..|                    |.|     |||.|
Zfish   197 SIVYLGMMVGAFFWGGMADKVGRRQCLLICMSLNGFFAFLSSFVQGYGLFLLCRMIAGFGIGGAV 261

  Fly   184 SVVCKDFPCFA--ASRFVAG-----------------LSMNYCFVPIY--ILTLENVGIKYRTLV 227
            .:|   |..||  .:|...|                 .:|.:..:|.|  |.|..:..|.|....
Zfish   262 PIV---FSYFAEVLAREKRGEHLSWLCMFWMIGEIYASAMAWAIIPHYGQITTASSQFINYHHYT 323

  Fly   228 GNLALTFFFTLGACLLPWLAYVISNWRHYAMVVALPIVFMILTSLLAPESPSWLMSVGKVDRCIE 292
                 ::.|::|:      ||...:||.:.:|.|||.|..::.....||||.:.:.|||.|....
Zfish   324 -----SWSFSMGS------AYQFHSWRVFVVVCALPCVCAVVALTFMPESPRFYLEVGKHDEAWM 377

  Fly   293 VMKEAAKAN-------------------------------GKIISEE----------VWSEMREC 316
            ::|:....|                               |...|:.          :|....:|
Zfish   378 ILKQIHDTNMRARGQPEKVFTVNRIKIPKQIDEFVEMHESGNFFSKAIFRIKTELHGIWLNFLKC 442

  Fly   317 --YELKFANEQLGKQYTSL------------DLFK----------------------TF------ 339
              |.:|.:..:|...:.:|            |:.|                      ||
Zfish   443 FNYPVKESTVKLAIVWLTLSFGYYGLSVWFPDVIKHLQNDEYASKGQRHNNERIEDFTFNFTLEN 507

  Fly   340 ----------PRLVVLTILIVTWMT------------------------VALAYDAHVRVVEILD 370
                      .|.:.:....||::.                        .|:.|:..:...::.:
Zfish   508 QIHTNSLFINDRFINMKFKSVTFINSTFQSCFFEDVTSVGSFFRNCTFIEAVFYNTDIDDSKLKN 572

  Fly   371 TDI--------------------------FITFSLSSLVEIPAGIVPMLLLDRIGRKPMMSAVML 409
            ||:                          |:.| |.:|..:|..||..||:|:|||..|:...|:
Zfish   573 TDVINSTFYHNKTGCQMTFEDDYSAYWVYFVNF-LGTLAVLPGNIVSALLMDKIGRLSMLGFSMI 636

  Fly   410 LCAASSLFVGILKGHWNASTAAIAARF------FATMAYNVGQQWASEILPTVLRGQGLAIINIM 468
            |...|..|:      |..::.::....      .:..|:|......:|:.||..||.|....|.:
Zfish   637 LSGISCFFL------WFGTSESMMIGMLCLYNGLSISAWNSLDVVTTELYPTDRRGTGFGFCNAL 695

  Fly   469 GQMGALLSPLVL-STHRYYRPLPMFIITLVSVIGALIILFLPETK 512
            .::.|::..|:. |.....:.:|:.:.:.|.|.|.|:.|.||:|:
Zfish   696 CKLAAVMGNLIFGSLVGITKAIPILLASSVLVGGGLVGLRLPDTR 740

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5592	NP_647996.1	2A0119	17..519	CDD:273328	125/695 (18%)
		MFS	141..509	CDD:119392	106/605 (18%)
sv2ca	NP_001121811.1	synapt_SV2	3..745	CDD:130366	125/695 (18%)
		Spt5_N	73..>141	CDD:288770	14/73 (19%)
		MFS	157..>360	CDD:119392	40/216 (19%)
		MFS	588..>711	CDD:119392	31/129 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.000