Protein Alignment CG5592 and SLC22A15

DIOPT Version :10

• Sequence 1: NP_647996.1
• Gene: CG5592 / 38662
• FlyBaseID: FBgn0035645
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: NP_060890.2
• Gene: SLC22A15 / 55356
• HGNCID: 20301
• Length: 547
• Species: Homo sapiens
• Alignment Length: 539
• Identity: 136/539 - (25%)
• Similarity: 232/539 - (43%)
• Gaps: 81/539 - (15%)

  Fly    16 IGDFGPFQKRLLFWMMPAAFLFAFTYFGQIFMILL----PKNHWCRVRELEGLPESEQKNRGIPK 76
            :|:.|.:|..|.|.:.....|:..|   :..:|.|    |..|| .:.||  ||.....|:.  .
Human    10 VGEMGIYQMYLCFLLAVLLQLYVAT---EAILIALVGATPSYHW-DLAEL--LPNQSHGNQS--A 66

  Fly    77 KQDGSFENCFMYNVPYDSNATNDANQTRSPIPCNNGWIYDRKEVPYESIATEYNWVCDKRDFGTY 141
            .:|.:|.:..:         |.:.::....:..::.         :.|||:|:..:.::    :|
Human    67 GEDQAFGDWLL---------TANGSEIHKHVHFSSS---------FTSIASEWFLIANR----SY 109

  Fly   142 SVVV----YFVGCIVGCLCFGFITDHSGR---------LPALF-LANSCSMIGGCVSVVCKDFPC 192
            .|..    :|.|..||.:.||.::|..||         |..|| :||..|          ..:..
Human   110 KVSAASSFFFSGVFVGVISFGQLSDRFGRKKVYLTGFALDILFAIANGFS----------PSYEF 164

  Fly   193 FAASRFVAGLSMNYCFVPIYILTLENVGIKYRTLVGNLALTFFFTLGACLLPWLAYVISNWRHYA 257
            ||.:||:.|:......:..::|..|.||..|..|.|::. ..||.:|......|.|.|.:||..|
Human   165 FAVTRFLVGMMNGGMSLVAFVLLNECVGTAYWALAGSIG-GLFFAVGIAQYALLGYFIRSWRTLA 228

  Fly   258 MVVALPIVFMILTSLLAPESPSWLMSVGKVDRCIEVMKEAAKANGKIISEEVWSEMREC-YELKF 321
            ::|.|....:.|.||..||||.||.|.|::....|.:...||.|.|:          :| :.|..
Human   229 ILVNLQGTVVFLLSLFIPESPRWLYSQGRLSEAEEALYLIAKRNRKL----------KCTFSLTH 283

  Fly   322 -ANEQLGKQYTSLDLFKTFPRLVVLTILIVTWMTVALAYDAHVRVVEILDTDIFITFSLSSLVEI 385
             ||....:..:.||||:....|....||:..|...:|.|.........|...|:...:||.|:||
Human   284 PANRSCRETGSFLDLFRYRVLLGHTLILMFIWFVCSLVYYGLTLSAGDLGGSIYANLALSGLIEI 348

  Fly   386 PAGIVPMLLLDR--IGRKPMMSAVMLLCAASSLFVGIL-----KGHW---NASTAAIAARFFATM 440
            |:..:.:.|:::  .|||..:||.:.|...:.|.|..|     .|.:   |:.:.::..:...:.
Human   349 PSYPLCIYLINQKWFGRKRTLSAFLCLGGLACLIVMFLPEKKDTGVFAVVNSHSLSLLGKLTISA 413

  Fly   441 AYNVGQQWASEILPTVLRGQGLAIINIMGQMGALLSPLVLSTHRYYRPLPMFIITLVSVIGALII 505
            |:|:...:.||:.|||:|..||...::..::|.:::|.:.|.......||..:.....:...|:.
Human   414 AFNIVYIYTSELYPTVIRNVGLGTCSMFSRVGGIIAPFIPSLKYVQWSLPFIVFGATGLTSGLLS 478

  Fly   506 LFLPETKGATMPQTLDEAE 524
            |.||||..:.:.:|..:.:
Human   479 LLLPETLNSPLLETFSDLQ 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5592	NP_647996.1	MFS_SLC22	113..509	CDD:340875	111/421 (26%)
SLC22A15	NP_060890.2	MFS_SLC22A15	71..469	CDD:340935	111/440 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	522..547