Protein Alignment CG5592 and Slc22a28

DIOPT Version :10

• Sequence 1: NP_647996.1
• Gene: CG5592 / 38662
• FlyBaseID: FBgn0035645
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: NP_001013842.2
• Gene: Slc22a28 / 434674
• MGIID: 3645714
• Length: 552
• Species: Mus musculus
• Alignment Length: 565
• Identity: 132/565 - (23%)
• Similarity: 243/565 - (43%)
• Gaps: 79/565 - (13%)

  Fly     9 YENFLLFIGDFGPFQKRLLFWMMPAAFLFAFTYFGQIFMILLPKNHWCRVRELEGLPESEQKNRG 73
            ::..|..:|..|.||...:.:::....|.......:.|...:| ||.|....|:....|:..:|.
Mouse     3 FQELLNQVGSLGRFQILQISFVLFLVGLVVPHITMENFTAAIP-NHRCWAPILDNDTASDNGSRI 66

  Fly    74 IPKKQDGSFENCFMYNVPYDSNATND-------------------ANQTRSPI-PCNNGWIYDRK 118
            :      |.::....::|.|||...|                   :|:|.... ||.:||:|||.
Mouse    67 L------SQDDLLRISIPLDSNLRLDKCRRFAQPQWHLLHLNGTFSNETEPDTEPCVDGWVYDRS 125

  Fly   119 EVPYESIATEYNWVCDKRDFGTYSVVVYFVGCIVGCLCFGFITDHSGRLPALFLANSCSMIGGCV 183
            .. ..:|.||::.||:.:...:.:...:.:|..:|.:..|.::|..||...|    :|:::...:
Mouse   126 NF-LSTIVTEWDLVCESQALNSVAKFSFMIGLFIGAIICGHLSDRFGRKFIL----TCALLQFAI 185

  Fly   184 SVVCKDF-PCF---AASRFVAGLSMNYCFVPIYILTLENVGIKYRTLVGNLALTFFFTLGACLLP 244
            :..|..| |.|   ...||:||:|:....|...:|.||....|:..:|..|. :...::|..:|.
Mouse   186 TETCVAFAPSFFIYCLLRFLAGMSVEPISVNSNLLILEWTNPKFLGMVAVLT-SCAASIGYMILA 249

  Fly   245 WLAYVISNWRHYAMVVALPIVFMILTSLLAPESPSWLMSVGKVDRCIEVMKEAAKANG------K 303
            .||::...|.|..:.:::||.|..:.:....||..||:...|..:.::.:::.|..||      .
Mouse   250 GLAFLFRIWHHLQLAMSVPIFFFFILTRWMSESARWLIVTNKPQKGLKELRKVAHMNGMKNSGNT 314

  Fly   304 IISEEVWSEMRECYELKFANEQLGKQYTSLDLFKTFP----RLVVLTILIVTWMTVALAYDAHVR 364
            :..|.|.:.|:.  ||:.|.    ::.:..|||.| |    |:.||:.:...:.........|
Mouse   315 LTMEVVEASMKN--ELEAAK----RKSSPRDLFHT-PILRNRICVLSFMRYLFTVSIFGLSLH-- 370

  Fly   365 VVEILDTDIFITFSLSSLVEIPAGIVPMLLLDRIGRKP------------MMSAVMLLCAASSLF 417
             ::.|.|:|.:...|||.:.|...::...:|:.:||:.            |::||.:.....:|.
Mouse   371 -LQHLSTNIILLRFLSSALGILISVIGHFVLNHMGRRITQLVLMSLRGIFMLTAVFVPQEMQTLR 434

  Fly   418 VGILKGHWNASTAAIAARFFATMAYNVGQQWASEILPTVLRGQGLAIINIMGQMGALLSPLVLST 482
            :.::       |.|.|   .:::...|.....:|:|||.||..|:.:|.:.|..|..|:||.:..
Mouse   435 IIVV-------TLAAA---LSSLCMCVSNLHINELLPTTLRATGMGVIGMFGNSGLFLAPLFMLL 489

  Fly   483 HRYYRPLPMFIITLVSVIGALIILFLPETKGATMPQTLDEAEKRW 527
            ..|...||.......|::....:..|||||...:|.::.:....|
Mouse   490 ATYSANLPWIFYGGFSILYGFSVFLLPETKNQPLPDSIHDVGNDW 534

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5592	NP_647996.1	MFS_SLC22	113..509	CDD:340875	100/421 (24%)
Slc22a28	NP_001013842.2	MFS_OAT	109..516	CDD:340932	104/432 (24%)