DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5592 and Orct

DIOPT Version :9

Sequence 1:	NP_647996.1	Gene:	CG5592 / 38662	FlyBaseID:	FBgn0035645	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_001262908.1	Gene:	Orct / 42891	FlyBaseID:	FBgn0019952	Length:	548	Species:	Drosophila melanogaster

Alignment Length:	529	Identity:	144/529 - (27%)
Similarity:	254/529 - (48%)	Gaps:	25/529 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 YENFLLFIGDFGPFQKRLLFWMMPAAFLFAFTYFGQIFMILLPKNHWCRVRELEGLPESEQK--N 71
            |::.:..:|:|||:|||:.:.:...|.:.||.....:|::..|........|...:.|....  |
  Fly     3 YDDVITHLGEFGPYQKRIYYLLCLPAIVCAFHKLAGVFLLAKPDFRCALPYENGSIYELSPHLWN 67

  Fly    72 RGIPKKQDGSFENCFMYNVPYDSNATN-----DANQTRSPIPCNNGWIYDRKEVPYESIATEYNW 131
            ...|:.     |.|..|:|.|.....|     .:|:|::   |:: ::|||.:. ..|..||:|.
  Fly    68 LSYPEN-----ERCSYYDVDYTEEYLNGSIPRSSNETKT---CSS-YVYDRSKY-LNSAVTEWNL 122

  Fly   132 VCDKRDFGTYSVVVYFVGCIVGCLCFGFITDHSGRLPALFLANSCSMIGGCVSVVCKDFPCFAAS 196
            ||.:......|..::.:|.::|.|.||.::|..||.|..|.:....:|.|.::.|..::..:..|
  Fly   123 VCSRSLLSATSDSLFMLGVLLGSLIFGQMSDKLGRKPTFFASLVLQLIFGVLAAVAPEYFSYTIS 187

  Fly   197 RFVAGLSMNYCFVPIYILTLENVGIKYRTLVGNLALTFFFTLGACLLPWLAYVISNWRHYAMVVA 261
            |.:.|.:.:..|:..|::.||.||..||...| :|:..||::|..|....||.|.:||...:.:.
  Fly   188 RMIVGATTSGVFLVAYVIALEMVGSSYRLFAG-VAMQMFFSVGFMLTAGFAYFIHDWRWLQIAIT 251

  Fly   262 LPIVFMILTSLLAPESPSWLMSVGKVDRCIEVMKEAAKANGKIISEEVWSEM-RECYELKFANEQ 325
            ||.:..:....:.|||..||:..|:.|....::::|||.|...:..|::.:: .|..|.|..:|.
  Fly   252 LPGLLFLCYYWIIPESARWLLMKGRKDEAFVIIEKAAKENKVEVPNEIYEQLVDEVAEKKKQDEM 316

  Fly   326 LGKQ--YTSLDLFKTFPRLVVLTILI-VTWMTVALAYDAHVRVVEILDTDIFITFSLSSLVEIPA 387
            ...|  .|..||.: :|.|...|:|| ..|...:..|.........|..:..:.|.:|..||||.
  Fly   317 AASQPAATVFDLLR-YPNLRRKTLLIFFDWFVNSGVYYGLSWNTNNLGGNQLVNFMISGAVEIPG 380

  Fly   388 GIVPMLLLDRIGRKPMMSAVMLLCAASSLFVGILKG--HWNASTAAIAARFFATMAYNVGQQWAS 450
            ..:.:..|:|.||:.::...|::...|.|....:..  :|.....|:..:...|.:|.....:::
  Fly   381 YTLLLFTLNRWGRRSILCGTMMVAGISLLATIFVPSDMNWLIVACAMIGKLAITSSYGTIYIFSA 445

  Fly   451 EILPTVLRGQGLAIINIMGQMGALLSPLVLSTHRYYRPLPMFIITLVSVIGALIILFLPETKGAT 515
            |..|||:|..||...:::.::|.:|:|.:......:||||:.|...:|:...|:.|.||||....
  Fly   446 EQFPTVVRNVGLGASSMVARVGGILAPYLKLLGEIWRPLPLIICGALSLTAGLLSLLLPETLNKP 510

  Fly   516 MPQTLDEAE 524
            ||:|:::.|
  Fly   511 MPETIEDGE 519

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5592	NP_647996.1	2A0119	17..519	CDD:273328	141/514 (27%)
CG5592	NP_647996.1	MFS	141..509	CDD:119392	101/373 (27%)
Orct	NP_001262908.1	2A0119	11..514	CDD:273328	141/514 (27%)
Orct	NP_001262908.1	MFS	135..491	CDD:119392	97/357 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45458413
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9N9
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	86	1.000	Inparanoid score	I1789
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
	7	6.890