DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5592 and CG7084

DIOPT Version :9

Sequence 1:	NP_647996.1	Gene:	CG5592 / 38662	FlyBaseID:	FBgn0035645	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_001247235.2	Gene:	CG7084 / 42606	FlyBaseID:	FBgn0038938	Length:	597	Species:	Drosophila melanogaster

Alignment Length:	536	Identity:	145/536 - (27%)
Similarity:	243/536 - (45%)	Gaps:	50/536 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 GDFGPFQKRLLF-WMMPAAFLFAFTYFGQIFMILLPKNHWCRV--RELEGLPESEQKNRGIPKKQ 78
            |:.|.:|....| ::...||..|..|...|..:.:| :|||.|  ||.......|.::..:||:.
  Fly    42 GNHGRYQTLYNFVFVGGLAFSGAMIYMNIILALNIP-DHWCTVPGRENTNFSLEEWRDITLPKQA 105

  Fly    79 DG----SFENCFMYNVPY----DSNATNDANQTRSPIPCNNGWIYDRKEVPYES-IATEYNWVCD 134
            |.    :|.||.|:.:.:    |.:|.| :|.|::...|.|||.||:  ..||| |.|::||||.
  Fly   106 DNRGRKTFSNCEMFQMNFSEITDWSAWN-SNLTKTTEACQNGWSYDK--TWYESTIPTDHNWVCA 167

  Fly   135 KRDFGTYSVVVYFVGCIVGCLCFGFITDHSGRLPALFLANSCSMIGGCVSVVC-KDFPCFAASRF 198
            |..|.|...||..|..:.|....|.:.|..||....:::.....:|...|::| ..:..|.....
  Fly   168 KDLFVTNVFVVGRVTEVAGSFILGQMGDSYGRRFVYYISVVFCSLGRLGSIMCTSSYTWFLIMSG 232

  Fly   199 VAGLSMNYCFVPIYILTLENVGIKYRTLVGNLALTFF----FTLGACLLPWLAYVISNWRHYAMV 259
            :.||::|..|....|:.:|....:.|:     .:.||    :::|..|:|.|.:.:.:|..:..:
  Fly   233 IVGLTVNSLFQSPQIIGMEISREEDRS-----RIAFFQSCGWSIGTTLMPLLYWWLRHWDSFMWL 292

  Fly   260 VALPIVFMILTSLLAPESPSWLMSVGKVDRCIEVMKEAAKANGKIISEEVWSEMRECYELKFANE 324
            .::|...::|.|....|||.||:|..:....|..:::.||.||... :....|:.|.|    :.:
  Fly   293 TSIPTAMVLLFSKYVIESPRWLISKQRFREAIVQLQKIAKINGHRF-DMTEKELAEIY----SRD 352

  Fly   325 QLGKQYTSLDLFKTFPRLVVLTILIVTWMTVALAYDAHVRVVEILDTDIFITFSLSSLVEIPAGI 389
            :....|....||..:......||:..:|..||::|...|.....:..:.|:.|...|:|||||.:
  Fly   353 KQDVTYGIASLFAGWRLARNTTIMGFSWCVVAVSYFTLVLFSSRMAGNPFLNFLYQSIVEIPAYV 417

  Fly   390 VPMLLLDRIGRKPMMSAVMLLCAASSLFVGILKGHWNAST----------AAIAARFFATMAYNV 444
            |...:.|..||:...|...|:...:.|.:.:.      ||          .|...:|...:.:..
  Fly   418 VGRYMGDTYGRRFTNSVSFLISFVTCLPIIVY------STDERYENLMIYLATFIKFLNALTFFT 476

  Fly   445 GQQWASEILPTVLRGQGLAIINIMGQMGALLSP--LVLSTHRYYRPLPMFIITLVSVIGALIILF 507
            ......||.||.:|..|:|:..|:.....:|:|  :.|.|....| .|.:|:.::.::|.:..||
  Fly   477 VNLQCLEIYPTCMRQTGVALGTILANAIGVLAPYLVYLGTTVDIR-APYYILGVLFLLGGIGALF 540

  Fly   508 LPETKGATMPQTLDEA 523
            ||||....:|.|::||
  Fly   541 LPETLHKKLPDTMEEA 556

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5592	NP_647996.1	2A0119	17..519	CDD:273328	142/530 (27%)
CG5592	NP_647996.1	MFS	141..509	CDD:119392	90/384 (23%)
CG7084	NP_001247235.2	2A0119	64..552	CDD:273328	136/508 (27%)
CG7084	NP_001247235.2	MFS	184..542	CDD:119392	87/374 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	86	1.000	Inparanoid score	I1789
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
	5	5.060