DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5592 and CG17752

DIOPT Version :9

Sequence 1:	NP_647996.1	Gene:	CG5592 / 38662	FlyBaseID:	FBgn0035645	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_650817.1	Gene:	CG17752 / 42337	FlyBaseID:	FBgn0038718	Length:	538	Species:	Drosophila melanogaster

Alignment Length:	553	Identity:	175/553 - (31%)
Similarity:	274/553 - (49%)	Gaps:	77/553 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 GDFGPFQKRLLFWMMPAAFLFAFT-------YFGQIFMILLPKNHWCRVRELEGLPESEQKNRGI 74
            |:|||:|..||       .|:.:|       ||.|..:...| :|.|      ..|..|
  Fly    11 GNFGPYQILLL-------GLYGYTNIVSSLHYFSQTLISFTP-SHRC------SAPVEE------ 55

  Fly    75 PKKQDGSFENCFMYN---------VPYDSNATNDANQTRSPIPCNNGWIYDRKEVPYESIATEYN 130
                       |..|         :.||.:.|:..:.     .|:: |.:| ||..||||.||..
  Fly    56 -----------FSQNFTELLSCSVIQYDVDMTSFRDN-----KCSS-WDFD-KESNYESITTELE 102

  Fly   131 WVCDKRDFGTYSVVV----YFVGCIVGCLCFGFITDHSGRLPALFLANSCSMIGGCVSVVCKDFP 191
            ||||    ..|.:.|    :|:|..:|.:.||::.|..|||||..|:......|...:......|
  Fly   103 WVCD----DAYKLAVGQSFFFIGSALGSIFFGYLADRIGRLPACVLSTLTGASGDFFTSFVGSLP 163

  Fly   192 CFAASRFVAGLSMNYCFVPIYILTLENVGIKYRTLVGNLALTFFFTLGACLLPWLAYVISNWRHY 256
            .|:.:||::||||:..:|.:|||..|.:..::||...|:.|..|:::|..:.||:|..:.|||.|
  Fly   164 MFSFTRFISGLSMDTQYVLMYILVFEYLSPQHRTFGLNIILGVFYSIGLMISPWIAIWLGNWRSY 228

  Fly   257 AMVVALPIVFMILTSLLAPESPSWLMSVGKVDRCIEVMKEAAKANGKIISEEVWSEMRECYELKF 321
            ....:||.:.|::..|...||..||::.||.|:.:..:|..||.||:.:.:.|:.|..:.|..|.
  Fly   229 LWAASLPALGMLIFPLFLHESVEWLLTKGKFDKAVNNLKSVAKFNGRQVEDSVFDEFIKHYREKL 293

  Fly   322 ANEQLGKQYTSLDLFKTFPRLVVLT-ILIVTWMTVALAYDAHVRVVEILDTDIFITFSLSSLVEI 385
            .:.|.....|.:.:.:| |||...| ||::..|.:.:|:|...|.||.:....|..||.|..|.:
  Fly   294 NSAQKKSSDTFMGMLRT-PRLRKFTIILLIKSMIITIAFDILSRNVEGVGISPFKLFSYSGFVVL 357

  Fly   386 PAGIVPMLLLDRIGRKPMMSAVMLLCAASSLFVGILKGHWNASTAAI-------AARFFATMAYN 443
            |.|:..:|..::||||.|..|.:|:.|..:...|.|.|..:.:..::       .|||.|.:||:
  Fly   358 PGGLSIILFQNKIGRKGMACASLLVGAFITATTGYLVGTLDPANYSVLLGFMVCLARFGAVVAYD 422

  Fly   444 VGQQWASEILPTVLRGQGLAIINIMGQMGALLSPLVLSTHRYYRPLPMFIITLVSVIGALIILFL 508
            ...|:|:||:||.:||:|:|.|:::|...|..|..::....:|:|||..:|:.:.:|||.:.|.|
  Fly   423 AEAQYAAEIIPTSVRGRGVANIHVVGNAFAFFSSYIIYLGTFYKPLPSLLISFLLIIGACLCLTL 487

  Fly   509 PETKGATMPQTLDEAE-----KRW-TLRCRDRK 535
            |||....:||||:|.|     ::| ...|..||
  Fly   488 PETLHKQLPQTLEEGEIFAKGEKWYFFPCFSRK 520

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5592	NP_647996.1	2A0119	17..519	CDD:273328	166/529 (31%)
CG5592	NP_647996.1	MFS	141..509	CDD:119392	124/379 (33%)
CG17752	NP_650817.1	2A0119	11..498	CDD:273328	166/529 (31%)
CG17752	NP_650817.1	MFS	116..488	CDD:119392	122/372 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45471397
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	86	1.000	Inparanoid score	I1789
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D284622at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
	6	6.000