DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5592 and CG17751

DIOPT Version :9

Sequence 1:	NP_647996.1	Gene:	CG5592 / 38662	FlyBaseID:	FBgn0035645	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_650816.3	Gene:	CG17751 / 42336	FlyBaseID:	FBgn0038717	Length:	533	Species:	Drosophila melanogaster

Alignment Length:	546	Identity:	168/546 - (30%)
Similarity:	266/546 - (48%)	Gaps:	87/546 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 GDFGPFQKRLLFWMMPAAFLFAFT-------YFGQIFMILLPKNHWCRVRELEGLPESEQKNRGI 74
            |:|||:|..||       .||.:|       ||.|..:...| :|.|      ..||..|.|
  Fly    11 GNFGPYQILLL-------GLFGYTNIVSSLHYFSQTIISFTP-SHRC------SRPEDYQPN--- 58

  Fly    75 PKKQDGSFENCFMYNVPYDSNATNDANQTRSPIPCNNGWIYDRKEVPYESIATEYNWVCDKRDFG 139
                ..|..:|.:.....:...|:              |.::| |..||||.||..||||    .
  Fly    59 ----STSLLSCSVMQFDKEFKCTS--------------WDFER-ESNYESITTELEWVCD----D 100

  Fly   140 TYSVVV----YFVGCIVGCLCFGFITDHSGRLPALFLANSCSMIGGCVSVVCKDFPCFAASRFVA 200
            .|.:.|    :|:|..:|.:.||::.|..|||||..|:......|...:......|.|:.:||::
  Fly   101 AYKLAVGQSFFFIGSALGSIFFGYLADRIGRLPACVLSTLTGASGDFFTSFVGSLPWFSFTRFIS 165

  Fly   201 GLSMNYCFVPIYILTLENVGIKYRTLVGNLALTFFFTLGACLLPWLAYVISNWRHYAMVVALPIV 265
            ||.|:..:|.:|||..|.:..::||...|:.|..|:.:|..:.||:|..::|||:|....:||.:
  Fly   166 GLFMDTQYVLMYILVFEYLSPQHRTFGLNIILGVFYCVGLMISPWIAIWVTNWRNYLWAASLPAL 230

  Fly   266 FMILTSLLAPESPSWLMSVGKVDRCIEVMKEAAKANGKIISEEVWSEMRECYELKFANEQLGKQY 330
            .|:|..:...||..||::.||.::..:.::..||.||:.:.:.|:.|..:.|..|..|.|.....
  Fly   231 GMLLFPVFLHESAEWLLTKGKFEKAEKSLRGVAKFNGRQVDDSVFDEFIKHYREKLNNSQNKSSD 295

  Fly   331 TSLDLFKTFPRLVVLT-ILIVTWMTVALAYDAHVRVVEILDTDIFITFSLSSLVEIPAGIVPMLL 394
            |.:.:.:| |||...| ||::..|.:.:|:|...|.||.:....|..||.|....:|||:..:|.
  Fly   296 TFMGMLRT-PRLRKFTIILLIKSMIITIAFDILSRNVEGVGISPFKLFSYSGFCYLPAGLTIILF 359

  Fly   395 LDRIGRKPMMSAVMLLCAASSLFVGILKGHWNASTAAIAA------------------RFFATMA 441
            .::||||.|        |.:|||||.:   ..|:|..:.|                  |:.|.:|
  Fly   360 QNKIGRKGM--------ACASLFVGAI---ITAATGYLVATLDPSDYSVLLGFMVSLGRYGAVVA 413

  Fly   442 YNVGQQWASEILPTVLRGQGLAIINIMGQMGALLSPLVLSTHRYYRPLPMFIITLVSVIGALIIL 506
            |:...|:|:||:||.::|:|:|.|:::|...|..|..::....:|:|||..:|:.:.:|||.:.|
  Fly   414 YDAEAQYAAEIIPTSVKGRGVANIHVVGNAFAFFSSYIIYLGTFYKPLPSLMISFILLIGACLCL 478

  Fly   507 FLPETKGATMPQTLDEAE-----KRW 527
            .||||....:||.|:|.|     ::|
  Fly   479 ALPETLHKNLPQNLEEGEMFAKGEKW 504

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5592	NP_647996.1	2A0119	17..519	CDD:273328	163/531 (31%)
CG5592	NP_647996.1	MFS	141..509	CDD:119392	122/390 (31%)
CG17751	NP_650816.3	2A0119	11..490	CDD:273328	162/530 (31%)
CG17751	NP_650816.3	MFS	109..481	CDD:119392	120/383 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45471404
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	1	1.010	-	-		D284622at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
	6	5.960