DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5592 and CG7342

DIOPT Version :9

Sequence 1:	NP_647996.1	Gene:	CG5592 / 38662	FlyBaseID:	FBgn0035645	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_001247196.1	Gene:	CG7342 / 42335	FlyBaseID:	FBgn0038716	Length:	540	Species:	Drosophila melanogaster

Alignment Length:	532	Identity:	173/532 - (32%)
Similarity:	274/532 - (51%)	Gaps:	58/532 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 GDFGPFQKRLLFWMMPAAFLFAFTYFGQIFMILLPKNHWCRVRELEGLP---ESEQKNRGIPKKQ 78
            |||...|..:|........|.|..|:.|..:..:|| :||    .:|||   ||...:..:|..:
  Fly    12 GDFSRLQMIMLLLFCVINVLSALHYYSQTIISFVPK-YWC----ADGLPASIESPVDSSCLPLNR 71

  Fly    79 DGSFEN-CFMYNVPYDSNATNDANQTRSPIPCNNGWIYDRKEVPYESIATEYNWVCDKRDFGTYS 142
            :.|..| |:.||  |:                    :|    :.|:|..:|.:|||......|..
  Fly    72 NISTPNTCYSYN--YE--------------------LY----MGYQSFPSEMDWVCADAWKLTLG 110

  Fly   143 VVVYFVGCIVGCLCFGFITDHSGRLPALFLANSCSMIGGCVSVVCKDFPCFAASRFVAGLSMNYC 207
            ..::|||.:||.:..|::.|..||||.|.:||..:|.|..:::...:...|...|.::|::.:..
  Fly   111 QSMFFVGSVVGSMVLGYLADVVGRLPILIVANLIAMTGNLLTIWSTNVTLFCMFRMISGIATDSN 175

  Fly   208 FVPIYILTLENVGIKYRTLVGNLALTFFFTLGACLLPWLAYVISNWRHYAMVVALPIVFMILTSL 272
            ||.:|||.:|.:....|||..::.:.||:.||:...||:|.::.:||.:.:..:||::.:....|
  Fly   176 FVMMYILVMEYMRPSVRTLGLSICIGFFYCLGSMAAPWIAVLMRSWRGFLLTTSLPLLVVPFFYL 240

  Fly   273 LAPESPSWLMSVGKVDRCIEVMKEAAKANGKIISEEVWSEMRECYELKFANEQLGKQYTSLDLFK 337
            :.|||..||:|..|.|..:..:|..||.||:.:.|..::|..|  |.|.:.:........||||:
  Fly   241 IVPESIQWLISKQKYDSAVVCLKRVAKINGRHVEESAYAEFIE--ECKCSQQNQKASPHLLDLFQ 303

  Fly   338 TFPRLVVLT-ILIVTWMTVALAYDAHVRVVEILDTDIFITFSLSSLVEIPAGIVPMLLLDRIGRK 401
            | |||...| ||....|.:.|.|||..|.|:.|....|:.||||:...:||.::.:.|.||||||
  Fly   304 T-PRLRRHTLILFFKSMVITLCYDAVSRNVQGLGISPFVMFSLSATAILPACLLIIALQDRIGRK 367

  Fly   402 PMMSAVMLLCAASSLFVGILKGHWNASTA-----------AIAARFFATMAYNVGQQWASEILPT 455
            .|.||.:||   |.:|:.:..|...|::|           ::..||..|:|||.|.|:|:|::||
  Fly   368 AMASASLLL---SGIFISVTGGIIFAASASDKTTTLLVSLSVVGRFGVTVAYNSGAQYATELIPT 429

  Fly   456 VLRGQGLAIINIMGQMGALLSPLVLSTHRYYRPLPMFIITLVSVIGALIILFLPETKGATMPQTL 520
            .:||||:|.:::.|......|..:|.|...:.|||..|:.::|::||.:.|.||||...|:|.:|
  Fly   430 CVRGQGVAAVHVAGYAFTFFSAYILFTRSVFSPLPEIILGVLSLLGACLCLLLPETLHRTLPTSL 494

  Fly   521 DEAEK-----RW 527
            ::.|.     ||
  Fly   495 EDGENFGKNDRW 506

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5592	NP_647996.1	2A0119	17..519	CDD:273328	169/517 (33%)
CG5592	NP_647996.1	MFS	141..509	CDD:119392	130/379 (34%)
CG7342	NP_001247196.1	2A0119	12..491	CDD:273328	168/515 (33%)
CG7342	NP_001247196.1	MFS	93..>243	CDD:119392	45/149 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45471403
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	86	1.000	Inparanoid score	I1789
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	1	1.010	-	-		D284622at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
	7	7.010