DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5592 and CG7333

DIOPT Version :9

Sequence 1:	NP_647996.1	Gene:	CG5592 / 38662	FlyBaseID:	FBgn0035645	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_650814.2	Gene:	CG7333 / 42334	FlyBaseID:	FBgn0038715	Length:	541	Species:	Drosophila melanogaster

Alignment Length:	519	Identity:	174/519 - (33%)
Similarity:	267/519 - (51%)	Gaps:	23/519 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 GDFGPFQKRLLFWMMPAAFLFAFTYFGQIFMILLPKNHWCRVRELEGLPESEQKNRGIPKKQDGS 81
            |::|.||..:|........|.:..||.|..:...|: |||...:|.||  |.:..|.:
  Fly    11 GNYGRFQVMILLLYGYTNILGSLHYFSQTLITFTPE-HWCFHADLNGL--SVEGIRSV------- 65

  Fly    82 FENCFMYNVPYDSNATNDANQTRSPIPCNNGWIYDRKEVPYESIATEYNWVCDKRDFGTYSVVVY 146
            :||....:........|......:...|.| ||::| |..||||.||..|||||..........:
  Fly    66 YENISASSCTPLLGVVNGTGVVSTNRKCRN-WIFNR-ESGYESITTELKWVCDKSHHPAVGQSFF 128

  Fly   147 FVGCIVGCLCFGFITDHSGRLPALFLANSCSMIGGCVSVVCKDFPCFAASRFVAGLSMNYCFVPI 211
            |:|.:||.:.||:::|..||||:|.:|..|...|..::......|.||.|||::|||.:..:..:
  Fly   129 FMGSVVGTIIFGYLSDQVGRLPSLLMATLCGATGDFITSFVHTLPWFAFSRFMSGLSTDTMYYLM 193

  Fly   212 YILTLENVGIKYRTLVGNLALTFFFTLGACLLPWLAYVISNWRHYAMVVALPIVFMILTSLLAPE 276
            |||..|.:..|.||...|:.|..|:..|....||.|..|.|||.|..:.:||.:.:::...|..|
  Fly   194 YILVFEYLSPKSRTFGLNIILAVFYCFGLMTSPWAAIWIGNWRRYLWLASLPALGVLIYPFLICE 258

  Fly   277 SPSWLMSVGKVDRCIEVMKEAAKANGKIISEEVWSEMRECY-ELKFANEQLGK-QYTSLDLFKTF 339
            |..||::..|.|..:..:|:.||.|.:.:.|.|:.|..:.| |.:..:.:|.. :.|.|.:|.|
  Fly   259 SAQWLLTKRKYDDAVICLKKVAKFNRRHVEESVFDEFVKYYRERELQDYKLNSHEDTFLAMFLT- 322

  Fly   340 PRLVVLTI-LIVTWMTVALAYDAHVRVVEILDTDIFITFSLSSLVEIPAGIVPMLLLDRIGRKPM 403
            |||...|: |:|..:.:.|:.|...|.:|.|.|..|..||.:|:|.:|||:..:||.::||||.|
  Fly   323 PRLRRFTLTLLVKSVIITLSCDVINRNMEGLGTSPFKLFSFTSIVYLPAGVAILLLQNKIGRKGM 387

  Fly   404 MSAVM----LLCAASSLFVGILKGHWNASTAAI---AARFFATMAYNVGQQWASEILPTVLRGQG 461
            ....:    |:..|:...:..|....||...||   ..||.||::|:...|:|:||:||.:|||.
  Fly   388 ACTALFVGGLITTATGFMIAHLDPTENALLLAIMVGLGRFGATVSYDAEIQYAAEIIPTSVRGQA 452

  Fly   462 LAIINIMGQMGALLSPLVLSTHRYYRPLPMFIITLVSVIGALIILFLPETKGATMPQTLDEAEK 525
            ::.|:::|...:.|:..|:...:||:|||...|:.:...||.:.|.||||....:|:||.:.||
  Fly   453 VSNIHVIGLASSSLAFYVIYLAQYYKPLPSIFISCLMFFGAGLCLTLPETLNKKLPETLADGEK 516

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5592	NP_647996.1	2A0119	17..519	CDD:273328	170/511 (33%)
CG5592	NP_647996.1	MFS	141..509	CDD:119392	127/377 (34%)
CG7333	NP_650814.2	2A0119	11..510	CDD:273328	170/511 (33%)
CG7333	NP_650814.2	MFS	126..499	CDD:119392	127/373 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45471405
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	1	1.010	-	-		D284622at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
	6	5.960