DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5592 and CG14857

DIOPT Version :9

Sequence 1:	NP_647996.1	Gene:	CG5592 / 38662	FlyBaseID:	FBgn0035645	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_650392.1	Gene:	CG14857 / 41791	FlyBaseID:	FBgn0038262	Length:	560	Species:	Drosophila melanogaster

Alignment Length:	537	Identity:	146/537 - (27%)
Similarity:	243/537 - (45%)	Gaps:	46/537 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 YENFLLFIGDFGPFQKRLLFWMMPAAFLFAFTYFGQIFMILLPKNHWCRVRELEGLPESEQKNRG 73
            ::..|...|..|.:|..::..:...||.....|:.|..:..:|: |||....||        ||
  Fly     3 FDQILEKCGSAGRYQYLMILLLGYIAFTTTVHYYSQNIIGFVPQ-HWCYHEALE--------NR- 57

  Fly    74 IPKKQDGSFENCFMYNVPYDSNAT------------NDANQTRSPIPCNNGWIYDRKEVPYESIA 126
                   |||.......|:...|:            ..:|:|     |.. |||: .:..:.|:.
  Fly    58 -------SFEEIAAIYAPFGKEASCTRLDKIEGDRVTVSNET-----CQR-WIYN-YDFGFRSMN 108

  Fly   127 TEYNWVCDKRDFGTYSVVVYFVGCIVGCLCFGFITDHSGRLPALFLANSCSMIGGCVSVVCKDFP 191
            .|.||||:..........::|:|.::|...||.:.|..||:.|:.|||.|..:|..::....:..
  Fly   109 AELNWVCNDAYKARIGQSLFFLGSLMGTFTFGVLGDRIGRVRAVILANQCGFVGDFLTTYASNLV 173

  Fly   192 CFAASRFVAGLSMNYCFVPIYILTLENVGIKYRTLVGNLALTFFFTLGACLLPWLAYVISNWRHY 256
            .||..|.::||:....:..::||.||.:..|.|.:..:..|...|.|||.:.|||:.:..|||.|
  Fly   174 QFAIFRCISGLAATANYYLMFILVLEYLAPKLRNMAISGTLGICFCLGALVAPWLSVLAGNWRIY 238

  Fly   257 AMVVALPIVFMILTSLLAPESPSWLMSVGKVDRCIEVMKEAAKANG-KIISEEVWSEMRECYELK 320
            ....||..:.:.|...:..||..||::...|:..|..:|..|..|| ::.:.:..:..|.|...:
  Fly   239 LTCSALLQLVVALFYFVVQESAQWLITRTNVEGAIARLKHIAHFNGMEVKAADFEAFRRNCIVKR 303

  Fly   321 FANEQLGKQYTSLDLFKTFPRLVVLTILIV-TWMTVALAYDAHVRVVEILDTDIFITFSLSSLVE 384
            ..:.|..:.....||.:| |.|..:::|:| |:|..:|:::...|.||.:....|:.|||.::|.
  Fly   304 KLSNQPEQTAGIFDLLRT-PNLRKVSLLVVFTFMLTSLSFNTISRNVEGMGLSPFVVFSLFAVVV 367

  Fly   385 IPAGIVPMLLLDRIGRKPMMSAVMLLCAASSLFVGILKGHWNAS-------TAAIAARFFATMAY 442
            .|:|.:..||..|:|||......||.....|..:|:......|.       ..|:..|...:|.|
  Fly   368 PPSGFIQGLLQSRVGRKATAFLAMLCTGLLSCALGVALSTEGAQKNVTLLLAFALPMRLGISMCY 432

  Fly   443 NVGQQWASEILPTVLRGQGLAIINIMGQMGALLSPLVLSTHRYYRPLPMFIITLVSVIGALIILF 507
            .|..|:|||:|||.:|.:|:|.:::.....:.:||.::.........|..|:.|:.:..:...|.
  Fly   433 TVTSQFASELLPTCVRSRGIAAVHLAAAGASFVSPYLIHLGTKLAAAPSLILALLLLTASGCTLM 497

  Fly   508 LPETKGATMPQTLDEAE 524
            ||||....:|.||.:.|
  Fly   498 LPETNNRQLPITLADGE 514

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5592	NP_647996.1	2A0119	17..519	CDD:273328	142/522 (27%)
CG5592	NP_647996.1	MFS	141..509	CDD:119392	105/376 (28%)
CG14857	NP_650392.1	2A0119	11..509	CDD:273328	142/522 (27%)
CG14857	NP_650392.1	MFS	126..470	CDD:119392	101/344 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45471399
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	86	1.000	Inparanoid score	I1789
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	1	1.010	-	-		D284622at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
	7	7.010