Protein Alignment CG5592 and slc22a2

DIOPT Version :10

• Sequence 1: NP_647996.1
• Gene: CG5592 / 38662
• FlyBaseID: FBgn0035645
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: NP_998315.1
• Gene: slc22a2 / 406424
• ZFINID: ZDB-GENE-040426-2167
• Length: 562
• Species: Danio rerio
• Alignment Length: 543
• Identity: 151/543 - (27%)
• Similarity: 259/543 - (47%)
• Gaps: 43/543 - (7%)

  Fly     9 YENFLLFIGDFGPFQKRLLFWMMPAAFLFAFTYFGQIFMILLPKNHWCR------VRELEGLPES 67
            :|..|...|.||..|.|:.......:..|:|.|.|.:|....|: ||||      :||..|....
Zfish     4 FEEILEEAGTFGRSQIRIFCTFCLVSIPFSFVYVGIVFQGFTPE-HWCRDPGVSEIRERCGWSLQ 67

  Fly    68 EQKNRGIP---KKQDGSFENCFMYNVPYDS------NATNDANQTR-SPIP---CNNGWIYDRKE 119
            :.:...:|   .....|:..|..::|.:::      |...|.||:: |.:|   |.:||.||  .
Zfish    68 DARRATVPLINGSSGASYSQCGRFDVDWNATGLSCENPDGDFNQSQLSVMPMMSCVDGWEYD--Y 130

  Fly   120 VPYESIATEYNWVCDKRDFGTYSVVVYFVGCIVGCLCFGFITDHSGRLPALFLANSCSMIGGCVS 184
            |..:|..||::.||....:.........:|.:||.:..|::.|..||:.:..:.|....:.|.:.
Zfish   131 VGRQSFVTEFDLVCGDAWYVDMFQATLSIGFLVGSIAIGYLADKYGRMKSFLMTNFFIGVTGILV 195

  Fly   185 VVCKDFPCFAASRFVAGLSMNYCFVPIYILTLENVGIKYRTLVGNLALTFFFTLGACLLPWLAYV 249
            ....::......|.:.|..:...::..|:|..|.||:.:|..|| :....||::|..|||.|||.
Zfish   196 ATSPNYISLLVFRALFGFGVKGGWMVGYVLITELVGVDHRRTVG-VTYQLFFSMGILLLPLLAYF 259

  Fly   250 ISNWRHYAMVVALPIVFMILTSLLAPESPSWLMSVGKVDRCIEVMKEAAKANGKIISEEVWSEMR 314
            |:|||...:|..:|.:..:......||||.||::..|:...:|:.|..||.|.|.:|:::.:
Zfish   260 ITNWRWLQVVFTVPYICFLTYYWFIPESPRWLLTQNKIAEAVEITKSIAKENRKTLSKKIET--- 321

  Fly   315 ECYELKFANEQLGKQYTSLDLFKTFPRLVVLTILIVTWMTVALAYDAHVRVVEILDTDIFITFSL 379
                ||..|...|...:.:|||||........||...|.|.|:.|...:..:.||..::::.|.:
Zfish   322 ----LKDDNIDSGSTASFMDLFKTAKLRTYTFILSFNWFTSAVVYQGLIMRLGILGGNVYVDFLI 382

  Fly   380 SSLVEIPAGIVPMLLLDRIGRKPMMSAVMLLCAASSLFVGILKG--HWNASTAAIAARFFATMAY 442
            |.:||:||..:.:|.::||||:...:...::..|:.|....:..  .|..|..|...|...|||:
Zfish   383 SGIVELPAAFLILLTIERIGRRLPFATANIVAGAACLITAFIPDSMFWLKSAVACVGRLGITMAF 447

  Fly   443 NVGQQWASEILPTVLRGQGLAIINIMGQMGALLSPLVLSTHRYYR------PLPMFIITLVSVIG 501
            .:.....:|:.|||:|..|:::.:.:..:|.:::|.:|     ||      .||:.|...::.:.
Zfish   448 EMVVFVNTELYPTVIRNLGVSVCSTLCDVGGIVAPFLL-----YRLAVIWLELPLIIFGALAFVA 507

  Fly   502 ALIILFLPETKGATMPQTLDEAE 524
            ..::|.||||||..:|:|:|:.|
Zfish   508 GGLVLLLPETKGVPLPETIDDIE 530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5592	NP_647996.1	MFS_SLC22	113..509	CDD:340875	109/403 (27%)
slc22a2	NP_998315.1	MFS_SLC22A1_2_3	116..515	CDD:340937	112/413 (27%)