Protein Alignment CG5592 and SLC22A

DIOPT Version :9

• Sequence 1: NP_647996.1
• Gene: CG5592 / 38662
• FlyBaseID: FBgn0035645
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: NP_649370.1
• Gene: SLC22A / 40437
• FlyBaseID: FBgn0037140
• Length: 568
• Species: Drosophila melanogaster
• Alignment Length: 556
• Identity: 143/556 - (25%)
• Similarity: 250/556 - (44%)
• Gaps: 61/556 - (10%)

  Fly     2 PPRDCE--KYENFLLFIGDFGPFQKRLLFWM--MPAAF--LFAFTYFGQIFMILLPKNHWCRVRE 60
            |.:|.|  ..:..|..:|.||.|| .::|.:  :|..|  :|:.||......:    .|.|.|.|
  Fly    18 PAKDSEDVTLDAILKHLGQFGRFQ-LIIFLLICLPMMFHAMFSVTYVFTAATV----THRCSVEE 77

  Fly    61 LEGLPESE----QKNRGIPKKQDGSFENCFMY---NVPYDSNATNDANQ---TRSPIPC-NNGWI 114
            .: ||.|.    ..|..|| |.....::|..|   .:|..:::.:..:.   |::...| :|.::
  Fly    78 CD-LPGSNYYEPHTNWSIP-KNGKDLDSCNRYTNSELPQWNHSVDICSADHFTKNKEACAHNEFV 140

  Fly   115 YDRKEVPYESIATEYNWVCDKR----DFGTYSVVVYFVGCIVGCLCFGFITDHSGRLPALFLANS 175
            :...||   :|:.::...||..    ..||.:.:..|.|..:|    ||:.|..||..::.|...
  Fly   141 FRDDEV---TISNDFGIFCDDEWKLSMVGTINNLGQFFGIPIG----GFVADRYGRSFSIALGGI 198

  Fly   176 CSMIGGCVSVVCKDFPCFAASRFVAGLSMNYCFVPIYILTLENVGIKYRTLVGNLALTFFFTLGA 240
            ...:.|.:......:..|....|:..::.:..:...:::.:|.||.|.|.|..:: :|.|:.:|.
  Fly   199 LGAVLGVIRSFSPSYGWFLVFEFLDNMTSSTLYSTCFVIGIELVGPKRRVLACSV-ITVFYAVGE 262

  Fly   241 CLLPWLAYVISNWRHYAMVVALPIVFMILTSLLAPESPSWLMSVGKVDRCIEVMKEAAKANGKII 305
            .||...|....:||....:...|.:.::....:.|||..||:|.||.:|...:::.||..|.:.:
  Fly   263 VLLAMSAKAFHDWRILLRITYGPSLILLAYFWILPESVRWLLSQGKEERAKNILRRAAHVNKREL 327

  Fly   306 SEEVWSEMRECYELKFANEQLGKQ-----YTSLDLFKTFPRLVVLTILIVTWMTVALAYDAHVRV 365
            .|.|..      :|..||....:|     :...:.||.|...:....|  .|:...|.|......
  Fly   328 PESVLD------KLVLANRDKLQQSSESRFPIREAFKNFKWRIANCSL--CWIVHVLVYYGLSLN 384

  Fly   366 VEILDTDIFITFSLSSLVEIPAGIVPMLLLDRIGRKPMMSAVML---LCAASSLFVG----ILKG 423
            |.:||.|.:..|:..:|||||...:|:|::||.||:..:..:||   ||...::|.|    :|:
  Fly   385 VVLLDGDKYNNFAYIALVEIPGFFMPLLIMDRFGRRYSLCGLMLASGLCCIGTIFTGADQPVLQ- 448

  Fly   424 HWNASTAAIAARFFATMAYNVGQQWASEILPTVLRGQGLAIINIMGQMGALLSPLVLSTHRYYRP 488
                ....:..:...|.::.|...:||||.||.||...|:..::||:.|::|:|......:||..
  Fly   449 ----LVLFLVGKLTITASFQVLYFFASEIYPTNLRNSLLSFCSMMGRFGSMLAPQTPLLAKYYAN 509

  Fly   489 LPMFIITLVSVIGALIILFLPETKGATMPQTLDEAE 524
            .|..:....:::..|:.||.|||....:|.|:.||:
  Fly   510 APAMLFAGAAIVSGLLTLFFPETTNVVLPTTVQEAD 545

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5592	NP_647996.1	2A0119	17..519	CDD:273328	136/532 (26%)
		MFS	141..509	CDD:119392	97/379 (26%)
SLC22A	NP_649370.1	2A0119	35..540	CDD:273328	136/532 (26%)
		MFS	146..530	CDD:119392	103/404 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45458510
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	86	1.000	Inparanoid score	I1789
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.990