Protein Alignment CG5592 and slc22a4

DIOPT Version :10

• Sequence 1: NP_647996.1
• Gene: CG5592 / 38662
• FlyBaseID: FBgn0035645
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: NP_989323.1
• Gene: slc22a4 / 394948
• XenbaseID: XB-GENE-5858686
• Length: 553
• Species: Xenopus tropicalis
• Alignment Length: 548
• Identity: 149/548 - (27%)
• Similarity: 265/548 - (48%)
• Gaps: 30/548 - (5%)

  Fly     9 YENFLLFIGDFGPFQKRLLFWMMPAAFLFAFTYFGQIFMILLPKNHWCRVRELEGLPESEQKNRG 73
            |:....|:|::|.:|..:.|.:..:.....|.....:|:..:|: |.|.:.|...| .:..:|..
 Frog     4 YDEATSFLGEWGRYQFMIFFLLSASIIPNGFNGMSVMFLAGIPE-HRCHIPESANL-SAAWRNAS 66

  Fly    74 IPKKQDGSFENCFMYNVPYDSNAT-------NDANQTR-SPIPCNNGWIYDRKEVPYESIATEYN 130
            || :|||....|..|.:...:|.:       .|.:.|. ...||.:||.|. |.:...:|.||::
 Frog    67 IP-RQDGQDSQCRRYRLGTLTNYSALGLLPGRDVDVTGIEQEPCLDGWNYS-KSLYLSTIVTEWD 129

  Fly   131 WVCDKRDFGTYSVVVYFVGCIVGCLCFGFITDHSGRLPALFLANSCSMIGGCVSVVCKDFPCFAA 195
            .||:....|..:..::|||.::|....|.::|..||...||:..:.......|.|....:..||.
 Frog   130 IVCENDWKGPLTTSLFFVGVLLGSFVSGQLSDSFGRKKILFVTMAIQTGFSIVQVFSTSWEMFAI 194

  Fly   196 SRFVAGLSMNYCFVPIYILTLENVGIKYRTLVGNLALTFFFTLGACLLPWLAYVISNWRHYAMVV 260
            ...:.|:.....:|..:||..|.:|...|.:...|....||.:|..:||..||.|.:||...:.:
 Frog   195 LFLIVGMGQISNYVAAFILGTEILGKSARIIFSTLGTCIFFAIGYMMLPLFAYFIRDWRTLLLAL 259

  Fly   261 ALPIVFMILTSLLAPESPSWLMSVGKVDRCIEVMKEAAKANGKIISEEVWSEMRECYELKFANEQ 325
            .:|.:|.|....:.||||.||:..|:::....::::|||.| ::.:..|   :.:..||:...|:
 Frog   260 TIPGLFCIPLWWIIPESPQWLICKGRLEEAEVIIRKAAKIN-RVPAPAV---IFKTTELEDIAER 320

  Fly   326 LGKQYTSLDLFKTFPRLVVLTILIVTWMTVALAYDAHVRVVEILDTDIFITFSLSSLVEIPAGIV 390
            ..:.||.|||.|||...::..:.:..|:..::.|.........|..|.|:...|.:.:|:|:.|.
 Frog   321 QKRSYTLLDLVKTFNVRIITIMTVFLWLITSIGYFGISLNTPNLHGDPFLNCFLLAAIEVPSNIF 385

  Fly   391 PMLLLDRIGRKPMM-------SAVMLLCAASSLFVGILKGHWNASTAAIAARFFATMAYNVGQQW 448
            ..|||..|.|:..|       ..|:||.....|.:.||     ::...:..:|..|.|:::...:
 Frog   386 AWLLLRYISRRYSMCGSLLLGGVVLLLIQLVPLDLQIL-----STVLVMVGKFGVTAAFSMVYVY 445

  Fly   449 ASEILPTVLRGQGLAIINIMGQMGALLSPLVLSTHRYYRPLPMFIITLVSVIGALIILFLPETKG 513
            .:|:.|||:|..|:.|.::..::|:::||..:....|.|.||..::..::|...:::||.|||.|
 Frog   446 TAELYPTVIRNTGVGIGSVSSRIGSVISPYFVYLGAYNRLLPYILMGSLTVANGILVLFFPETFG 510

  Fly   514 ATMPQTLDEAEKRWTLRCRDRKIN-EDL 540
            ..:|:|:::.:....|.|| |||: ||:
 Frog   511 KPLPETIEQTQSIKGLCCR-RKIHREDI 537

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5592	NP_647996.1	MFS_SLC22	113..509	CDD:340875	108/402 (27%)
slc22a4	NP_989323.1	2A0119	12..516	CDD:273328	138/516 (27%)