Protein Alignment CG5592 and SLC22A25

DIOPT Version :9

• Sequence 1: NP_647996.1
• Gene: CG5592 / 38662
• FlyBaseID: FBgn0035645
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: XP_016873173.1
• Gene: SLC22A25 / 387601
• HGNCID: 32935
• Length: 577
• Species: Homo sapiens
• Alignment Length: 603
• Identity: 128/603 - (21%)
• Similarity: 244/603 - (40%)
• Gaps: 131/603 - (21%)

  Fly     9 YENFLLFIGDFGPFQ-KRLLFWMMPAAFLFAFTYFGQIFMILLPKNHWCRVRELEGLPESEQKNR 72
            :::.|..:|..|.|| .:::|.:|....::..|........:|  :|.|.|..|:        |.
Human     3 FQDLLDQVGGLGRFQILQMVFLIMFNVIVYHQTQLENFAAFIL--DHRCWVHILD--------ND 57

  Fly    73 GIPKKQDG--SFENCFMYNVPYDSNATNDA------------------NQTRSP--IPCNNGWIY 115
            .||....|  |.:.....::|:|||...:.                  ..|..|  .||.:||:|
Human    58 TIPDNDPGTLSQDALLRISIPFDSNLRPEKCRRFVHPQWKLIHLNGTFPNTSEPDTEPCVDGWVY 122

  Fly   116 DRKEVPYESIATEYNWVCDKRDFGTYSVVVYFVGCIVGCLCFGFITDHS---------------- 164
            |:...| .:|.|:::.||:.:...:.:..::..|.:||...:|.::|..
Human   123 DQSSFP-STIVTKWDLVCESQPLNSVAKFLFMAGMMVGGNLYGHLSDRKPLSSPNHVSTDCDEGL 186

  Fly   165 --------------GR-------LPALFLANSCSMIGGCVSVVCKDFPCFAASRFVAGLSMNYCF 208
                          ||       ...|.:..:|:.....:.|.|       :.||:||.:.....
Human   187 EVPIAIHQHHVFWFGRKFVLRWSYLQLAIVGTCAAFAPTILVYC-------SLRFLAGAATFSII 244

  Fly   209 VPIYILTLENVGIKYRTLVGNLALTFFFTLGACLLPWLAYVISNWRHYAMVVALP-IVFMILTSL 272
            |...:|.:|.:..::..:...|.|. ..::|...|..||:||.:.....:|::.| .||.:.:..
Human   245 VNTVLLIVEWITHQFCAMALTLTLC-AASIGHITLGSLAFVIRDQCILQLVMSAPCFVFFLFSRW 308

  Fly   273 LAPESPSWLMSVGKVDRCIEVMKEAAKANGKIISEEVW------SEMRECYELKFANEQLGKQYT 331
            || ||..||:...|.:..::.:::||..||...:|::.      |.|::  ||:.|.    |:::
Human   309 LA-ESARWLIINNKPEEGLKELRKAAHRNGMKNAEDILTMEVLKSTMKQ--ELEAAQ----KKHS 366

  Fly   332 SLDLFK--------TFPRLVVLTILIVTW-MTVALAYDAHVRVVEILDTDIFITFSLSSLVEIPA 387
            ..:|.:        .|...|.....|..| :|:.|.:         |..::|:..:|...|.:.|
Human   367 LCELLRIPNICKRICFLSFVRFASTIPFWGLTLHLQH---------LGNNVFLLQTLFGAVTLLA 422

  Fly   388 GIVPMLLLDRIGRKPMMSAVMLL---CAASSLFVG--------ILKGHWNASTAAIAARFFATMA 441
            ..|....|:.:.|:.....:|.|   |..:.:||.        :|      :|..:.|   |::.
Human   423 NCVAPWALNHMSRRLSQMLLMFLLATCLLAIIFVPQEMQTLRVVL------ATLGVGA---ASLG 478

  Fly   442 YNVGQQWASEILPTVLRGQGLAIINIMGQMGALLSPLVLSTHRYYRPLPMFIITLVSVIGALIIL 506
            ........:|::|:::||:...|......:|..|:.|::....|.||||..|..:.:::..|::|
Human   479 ITCSTAQENELIPSIIRGRATGITGNFANIGGALASLMMILSIYSRPLPWIIYGVFAILSGLVVL 543

  Fly   507 FLPETKGATMPQTLDEAE 524
            .||||:...:..::.:.|
Human   544 LLPETRNQPLLDSIQDVE 561

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5592	NP_647996.1	2A0119	17..519	CDD:273328	126/588 (21%)
		MFS	141..509	CDD:119392	88/431 (20%)
SLC22A25	XP_016873173.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153676
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.940