Protein Alignment CG5592 and Slc22a20

DIOPT Version :10

• Sequence 1: NP_647996.1
• Gene: CG5592 / 38662
• FlyBaseID: FBgn0035645
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: NP_941052.1
• Gene: Slc22a20 / 381203
• MGIID: 2685809
• Length: 556
• Species: Mus musculus
• Alignment Length: 560
• Identity: 136/560 - (24%)
• Similarity: 238/560 - (42%)
• Gaps: 79/560 - (14%)

  Fly     9 YENFLLFIGDFGPFQKRLLF---WMMPAAFLFAFTYFGQIFMILLPKNH---------------- 54
            :.:.|..:|..|.||  |::   .::|...|...|:. |.|....|.:|
Mouse     3 FTDLLDALGGVGRFQ--LVYTALLLLPCGLLACHTFL-QNFTAAAPPHHCQHPANYTEPTTNVSG 64

  Fly    55 -WCRVRELEGLPESEQKNRGIPKKQDGSFENCFMYNVP----YDSNATNDANQTRSPIPCNNGWI 114
             |.|.              .||..|.|..|.|..|..|    ...||::....|..   |.:||:
Mouse    65 VWLRA--------------AIPLNQHGDPEPCRRYVEPQWALLKPNASSHGVATEG---CKDGWV 112

  Fly   115 YDRKEVPYESIATEYNWVCDKRDFGTYSVVVYFVGCIVGCLCFGFITDHSGRLPALFLANSCSMI 179
            |||...| .:|..|::.||:.|.....:..:|..|.:||...||.:.|..||...|..:.....:
Mouse   113 YDRSIFP-STIVMEWDLVCEARTLRDLAQSIYMSGVLVGAALFGGLADRLGRKAPLVWSYLQLAV 176

  Fly   180 GGCVSVVCKDFPCFAASRFVAGLSMNYCFVPIYILTLENVGIKYRTLVGNLALTFFFTLGACLLP 244
            .|..:.....|..:...||:.|::.:...:....|.:|.:..:.||:.| :.|.|.||||..:|.
Mouse   177 SGAATAYVGSFSAYCVFRFLMGMTFSGIILNSLSLVVEWMPTRGRTVAG-ILLGFSFTLGQLILA 240

  Fly   245 WLAYVISNWRHYAMVVALPIVFMILTSLLAPESPSWLMSVGKVDRCIEVMKEAAKANG-KIISEE 308
            .:||:|..||.....|:.|.:...|.|...|||..||:..||..:.::.:::.|..|| |...|.
Mouse   241 GVAYLIRPWRWLQFAVSAPFLVFFLYSWWLPESSRWLLLHGKAQQAVQNLQKVAMMNGRKAEGER 305

  Fly   309 VWSEMRECY-ELKFANEQLGKQYTSLDLFKTFPRLVVLTILIVTWMTVALAYDAHVRVVEILDTD 372
            :.:|:...| :.:||:.:...  :.||||:|.....|...|:..|.:.::||......::.....
Mouse   306 LTTEVVSSYIQDEFASVRTSN--SILDLFRTPAIRRVTCCLMGVWFSNSVAYYGLAMDLQKFGLS 368

  Fly   373 IFITFSLSSLVEIPAGIVPMLLLDRIGRKPMMSAVMLLC---AASSLFV------------GILK 422
            |::..:|..:::|||.:|....:..:||:..:|:.::|.   ..:::|:            .:.|
Mouse   369 IYLVQALFGIIDIPAMLVATTTMIYVGRRATVSSFLILAGLMVIANMFMPEDLQTLRTVQAALGK 433

  Fly   423 GHWNASTAAIAARFFATMAYNVGQQWASEILPTVLRGQGLAIINIMGQMGALLSPLVLSTHRYYR 487
            |       .:|:.|.....:      ..|:.||.:|..|:...::..::|.|::||:.:......
Mouse   434 G-------CLASSFICVYLF------TGELYPTEIRQMGMGFASVNARLGGLVAPLITTLGEISP 485

  Fly   488 PLPMFIITLVSVI-GALIILFLPETKGATMPQTLDEAEKR 526
            .||.......||: |..:..||.||:...:.:|:...|:|
Mouse   486 VLPPVSFGATSVLAGMAVACFLTETRNVPLVETIAAMERR 525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5592	NP_647996.1	MFS_SLC22	113..509	CDD:340875	102/413 (25%)
Slc22a20	NP_941052.1	MFS_SLC22A6_OAT1_like	103..508	CDD:341004	105/424 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	526..556		136/560 (24%)