DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5592 and CG31272

DIOPT Version :9

Sequence 1:	NP_647996.1	Gene:	CG5592 / 38662	FlyBaseID:	FBgn0035645	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_650013.3	Gene:	CG31272 / 326130	FlyBaseID:	FBgn0051272	Length:	563	Species:	Drosophila melanogaster

Alignment Length:	588	Identity:	112/588 - (19%)
Similarity:	208/588 - (35%)	Gaps:	172/588 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    64 LPESEQKNRGIPKKQDGSFENCFMYNVPYDSNATNDANQTRS----------------------- 105
            :||   |::|:...:|....:        ||.|..:|..|..
  Fly    10 IPE---KSKGLENDKDADGNS--------DSTAEAEATPTEEGSATFDKAIEGAGFGIFNLMLLI 63

  Fly   106 -PIPCNNGWIYDRKEVPYESIATEYNWVCDKR----DFGTYSVVVYFVGCIVGCLCFGFITDHSG 165
             .||..:..|::...:.|.....|    ||.|    |.|..:.|.| .|..:..:.:|::.|..|
  Fly    64 VSIPAQSAAIFESSSMSYILPIAE----CDLRLTLEDKGVLNAVAY-AGMTISAIAWGYLADTKG 123

  Fly   166 RLPAL---FLANSCSMIGGCVSVVCKDFPCFAASRFVAGLSMNYCFVPIYILTLENVGIKYRT-- 225
            |...|   :|.::..:.|..:|   ::|......:|:.||.:|.....::....|..|.|:|:
  Fly   124 RKKILYWGYLIDAVCVFGSALS---QNFSMLVMFKFLGGLVVNGPAAVLFTYLTEMHGPKHRSSV 185

  Fly   226 --LVGNLALTFFFTLGACLLPWLAY-----------VISNWRHYAMVVALPIVFMILTSLLAPES 277
              :||.:..|  .|:...||.|..:           .:.:|:.:..|:.:|.:...|.....|||
  Fly   186 LMIVGMVTST--ATVSLPLLAWGIFPRDWDFEFWGLQVHSWQIFLFVLGIPSLISGLIFCSMPES 248

  Fly   278 PSWLMSVGKVDRCIEVMKE-------------------------------------------AAK 299
            |.:||:.|:.:..::..|:                                           ..|
  Fly   249 PRFLMAQGRNEEALQAFKQIYHVNTRKPKDSYPIKALIQEVPNRKAAQNEVIYTIEEKSGEVPTK 313

  Fly   300 ANGKIISEEVWSEMRE---------------CYELKFANEQLGKQYTSLDLFKTFPRL------- 342
            ...:.::|.:.:.:::               ||.::| ...||.....|.|.:.|..:
  Fly   314 RQSRTLAESLRAGLQQMKPLVRKPLLGLAICCYVMQF-GIFLGMNTIRLWLPQLFASMAEYEALH 377

  Fly   343 ----------VVLTILIVTWMTVALAYDAHVRVVEILDTDIFITFSLSSLVEIPAGIVPML---- 393
                      .:|...:......||.|.......:::..|::    |::::....|.|...
  Fly   378 AGDGLDVSMCTILEFSVNQTAETALNYADACSEPKVISMDMY----LNNIIVSATGFVGYFFAGG 438

  Fly   394 LLDRIGRKPMMS---------AVMLLCAASSLFVGILKGHWNASTA-AIAARFFATMAYNVGQQW 448
            :|..:|.|.||:         .:||..:.|||...|:...:...|. |:::...|.:|
  Fly   439 ILRALGPKRMMTYGLFLSGTFGLMLYFSVSSLMTLIVSATFLTITGIAVSSLLGAVVA------- 496

  Fly   449 ASEILPTVLRGQGLAIINIMGQMGALLSPLVLSTHRYYRPLPMFI-ITLVSVIGALIILFLPETK 512
               :.||.||...:||..:.|:.|||...|:.........||.|| ::.|.::..::.:.||:..
  Fly   497 ---LFPTQLRTVVVAIAMMCGRFGALSGNLLFPVFVQTGCLPPFIMVSSVLILSGILSISLPDPA 558

  Fly   513 GAT 515
            .||
  Fly   559 KAT 561

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5592	NP_647996.1	2A0119	17..519	CDD:273328	112/588 (19%)
CG5592	NP_647996.1	MFS	141..509	CDD:119392	88/475 (19%)
CG31272	NP_650013.3	MFS	62..555	CDD:119392	98/517 (19%)
CG31272	NP_650013.3	2A0115	74..524	CDD:273327	89/474 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45458467
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940