Protein Alignment CG5592 and Slc22a4

DIOPT Version :9

• Sequence 1: NP_647996.1
• Gene: CG5592 / 38662
• FlyBaseID: FBgn0035645
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: NP_062661.1
• Gene: Slc22a4 / 30805
• MGIID: 1353479
• Length: 553
• Species: Mus musculus
• Alignment Length: 539
• Identity: 141/539 - (26%)
• Similarity: 264/539 - (48%)
• Gaps: 26/539 - (4%)

  Fly     9 YENFLLFIGDFGPFQKRLLFWMMPAAFL-FAFTYFGQIFMILLPKNHWCRVRELEGLPESEQKNR 72
            |:..:.|:|::|||| ||:|:::.|:.: ..|.....:|:...|: |.|.|.:...| .|..:|.
Mouse     4 YDEVIAFLGEWGPFQ-RLIFFLLSASIIPNGFNGMSVVFLAGTPE-HRCLVPDTVNL-SSSWRNH 65

  Fly    73 GIP-KKQDGSF--ENCFMYNVPYDSNATN---------DANQTRSPIPCNNGWIYDRKEVPYESI 125
            .|| :.:||..  ::|..|.:...:|.:.         |..|.... .|.:||.|| |::...:|
Mouse    66 SIPLETKDGRQVPQSCRRYRLATIANFSAMGLEPGQDVDLEQLEQE-SCLDGWEYD-KDIFLSTI 128

  Fly   126 ATEYNWVCDKRDFGT-YSVVVYFVGCIVGCLCFGFITDHSGRLPALFLANSCSMIGGCVSVVCKD 189
            .||:|.||:. |:.| .:..::|||.:.|....|.::|..||...||...:.......|.:...:
Mouse   129 VTEWNLVCED-DWKTPLTTSLFFVGVLCGSFVSGQLSDRFGRKKVLFATMAVQTGFSFVQIFSTN 192

  Fly   190 FPCFAASRFVAGLSMNYCFVPIYILTLENVGIKYRTLVGNLALTFFFTLGACLLPWLAYVISNWR 254
            :..|.....:.|:.....:|..:||..|.:....|.:...|.:..||.:|..:||..||.|.:||
Mouse   193 WEMFTVLFAIVGMGQISNYVVAFILGTEILSKSVRIIFSTLGVCTFFAIGYMVLPLFAYFIRDWR 257

  Fly   255 HYAMVVALPIVFMILTSLLAPESPSWLMSVGKVDRCIEVMKEAAKANGKIISEEVWSEMRECYEL 319
            ...:.:.||.:|.:......||||.||:|..:.....:::::|||.|..:....::..:    ||
Mouse   258 MLLLALTLPGLFCVPLWWFIPESPRWLISQRRFAEAEQIIQKAAKMNSIVAPAGIFDPL----EL 318

  Fly   320 KFANEQLGKQYTSLDLFKTFPRLVVLTILIVTWMTVALAYDAHVRVVEILDTDIFITFSLSSLVE 384
            :..|....::...||||:|.....:..:.::.||..::.|.|....|..|..|:::...||.|:|
Mouse   319 QELNSLKQQKVIILDLFRTRNIATITVMAVMLWMLTSVGYFALSLNVPNLHGDVYLNCFLSGLIE 383

  Fly   385 IPAGIVPMLLLDRIGRKPMMSAVMLLCAASSLFVGILKGHWNASTAAIA--ARFFATMAYNVGQQ 447
            :||.....|||..:.|:.:::.|:.......|.:.::...:|..:..:.  .:|..|.|:::...
Mouse   384 VPAYFTAWLLLRTLPRRYIIAGVLFWGGGVLLLIQVVPEDYNFVSIGLVMLGKFGITSAFSMLYV 448

  Fly   448 WASEILPTVLRGQGLAIINIMGQMGALLSPLVLSTHRYYRPLPMFIITLVSVIGALIILFLPETK 512
            :.:|:.||::|...:.|.::..::|::::|..:....|.|.||..::..::|:..:|.||.||:.
Mouse   449 FTAELYPTLVRNMAVGITSMASRVGSIIAPYFVYLGAYNRLLPYILMGSLTVLIGIITLFFPESF 513

  Fly   513 GATMPQTLDEAEKRWTLRC 531
            |.|:|:.|::.:|....||
Mouse   514 GVTLPENLEQMQKVRGFRC 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5592	NP_647996.1	2A0119	17..519	CDD:273328	135/517 (26%)
		MFS	141..509	CDD:119392	89/369 (24%)
Slc22a4	NP_062661.1	2A0119	12..519	CDD:273328	134/516 (26%)
		MFS	123..510	CDD:119392	97/391 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167843865
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9N9
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.850