Protein Alignment CG5592 and Slc22a22

DIOPT Version :10

• Sequence 1: NP_647996.1
• Gene: CG5592 / 38662
• FlyBaseID: FBgn0035645
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: NP_001013969.1
• Gene: Slc22a22 / 299944
• RGDID: 1304605
• Length: 555
• Species: Rattus norvegicus
• Alignment Length: 572
• Identity: 141/572 - (24%)
• Similarity: 247/572 - (43%)
• Gaps: 73/572 - (12%)

  Fly     9 YENFLLFIGDFGPFQKRLLFWMMPAAFLFAFTY----FGQIFMILLPKNHWCRVRELE------- 62
            ::..|..:||.|.||    .||:....:.:...    ..:.|...:|.:| |.|..|:
  Rat     3 FDEILHHVGDRGRFQ----IWMIVVLNILSMVSSLHDVIENFTAAIPAHH-CSVNLLDTSRSEIS 62

  Fly    63 ---GLPESEQKNRGIPKKQDGSFENCFMYNVP----YDSNATNDANQTRSPIPCNNGWIYDRKEV 120
               .|.........||...:...|.|..:..|    .|||.:...:......||.:||.||. .|
  Rat    63 MAMNLTTEAMMKVSIPMGPNQKPEQCRRFRHPQWQFIDSNISTSNSTELETEPCLDGWTYDH-SV 126

  Fly   121 PYESIATEYNWVCDKRDFGTYSVVVYFVGCIVGCLCFGFITDHSGRLPALFLANSCSMIGGCVSV 185
            ...:|.||::.|||.:.|..|:......|..|.....|.|:|..||.|.|..   ||:..|.:..
  Rat   127 FTSTIVTEWDLVCDFQSFKYYAQATSLAGHFVAAPFCGIISDRFGRKPLLMY---CSLAYGILGT 188

  Fly   186 VC---KDFPCFAASRFVAGLSMNYCFVPIYILTLENVGIKYRTLVGNLALT-FFFTLGACLLPWL 246
            .|   .:|..:...||::..|.:...:...||.||...:::...|  :.|: .|.:.|...|..|
  Rat   189 CCAFVPNFSLYCVLRFLSSASASTVGMNCLILVLEETSVQWHATV--IVLSGLFSSTGLAGLGGL 251

  Fly   247 AYVISNWRHYAMVVALPIVFMILTSLLAPESPSWLMSVGKVDRCIEVMKEAAKANGK------II 305
            |||:|:|....:..|||.....:.....|||..|||..||.|:.::.::..|..|||      :.
  Rat   252 AYVLSDWHLIQLTSALPYFIFFILFCWVPESARWLMITGKTDQALKELQRIASINGKKDIAQNLT 316

  Fly   306 SEEVWSEMRE--CYELK-FANEQLGKQYTSLDLFKTFPRLVVL---TILIVTWMTV-ALAYDAHV 363
            :|::.|:::|  |..:| |:.:.:        :.....|.:||   ::|.....:: .|..|.|
  Rat   317 TEDLRSKVKEDVCSTVKHFSIKDI--------IINPMIRKIVLCYSSVLFAELFSIFGLLLDVH- 372

  Fly   364 RVVEILDTDIFITFSLSSLVEIPAGIVPMLLLDRIGRKPMMSAVMLL---CAASSLFVG----IL 421
                :|..:||:|..|..:::||:..:...:|..:.|:|:::.::..   |...::|:.    :|
  Rat   373 ----MLGKNIFVTQILLGVIDIPSKSLTYFILRNVRRRPLIAFLLFATGGCITITMFLSEDMYVL 433

  Fly   422 KGHWNASTAAIAARFFATMAYNVGQQWASEILPTVLRGQGLAIINIMGQMGALLSPLVLSTHRYY 486
            :    .:...:....||.. .::...:.:|:.|..||.....|...:.::.::||.|.|.|.:|:
  Rat   434 R----LAIFILGKGCFAAF-ISINTAYCNELSPVPLRSTLNGIYISVARLASVLSALTLVTRKYF 493

  Fly   487 RPLPMFIITLVSVIGALIILFLPETKGATMPQTLDEAEKRWTLRCRDRKINE 538
            ..|||....::.::..:.|.|||||....:..|:.:.|||  .|...:.|:|
  Rat   494 VLLPMIFCGVLPIVATINIYFLPETFNHPITDTIKDMEKR--NRLMSKNISE 543

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5592	NP_647996.1	MFS_SLC22	113..509	CDD:340875	104/419 (25%)
Slc22a22	NP_001013969.1	MFS_OAT	109..516	CDD:340932	107/430 (25%)